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| Protein General Information (TTD Target) |
Top |
| Full Name |
Toll-like receptor 4 (TLR4)
|
Clinical trial
|
Target Info
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| UniProt ID |
TLR4_HUMAN
|
| Gene Name |
TLR4
|
| Gene ID |
7099
|
| Interacting TTD Target Information |
Top |
| Interacting Literature-reported Target(s) |
Myeloid differentiation primary response protein MyD88 (MYD88) |
Target Info
|
PPI Info
|
[1] |
| Interacting Patented-recorded Target(s) |
Toll/interleukin-1 receptor domain-containing adapter (TIRAP) |
Target Info
|
PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Murine TOLL-like receptor 4 confers lipopolysaccharide responsiveness as determined by activation of NF kappa B and expression of the inducible cyclooxygenase. J Biol Chem. 2000 Nov 3;275(44):34035-40.
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| REF 2 |
TIRAP: an adapter molecule in the Toll signaling pathway. Nat Immunol. 2001 Sep;2(9):835-41.
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