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Protein General Information |
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Full Name |
E3 ubiquitin-protein ligase SH3RF1 (SH3RF1)
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UniProt ID |
SH3R1_HUMAN
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Gene Name |
SH3RF1
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Gene ID |
57630
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Interacting TTD Target Information |
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Interacting Literature-reported Target(s) |
RAC-beta serine/threonine-protein kinase (AKT2) |
Target Info
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PPI Info
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[1] |
Ras-related C3 botulinum toxin substrate 1 (RAC1) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
Regulation of the Pro-apoptotic scaffolding protein POSH by Akt. J Biol Chem. 2007 Jul 27;282(30):21987-97.
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REF 2 |
Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein. J Biol Chem. 2012 Jan 13;287(3):2247-56.
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