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| Target General Information |
Top |
| Target ID |
T94621 |
Target Info
|
| Target Name |
RAC-beta serine/threonine-protein kinase (AKT2) |
| Synonyms |
RAC-PK-beta; Protein kinase B beta; Protein kinase Akt-2; PKB beta |
| Target Type |
Literature-reported Target |
| Gene Name |
AKT2 |
| Biochemical Class |
Kinase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Acyltransferases |
[+] 1 Acyltransferases |
+ |
| Interacting Protein Name |
E3 ubiquitin-protein ligase SH3RF1 (SH3RF1) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
POSH; RNF142; SH3MD2 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Biochemical Activity |
[1] |
| 2 |
Yeast two hybrid |
[2] |
| References |
Top |
| REF 1 |
Regulation of the Pro-apoptotic scaffolding protein POSH by Akt. J Biol Chem. 2007 Jul 27;282(30):21987-97.
|
| REF 2 |
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex. J Biol Chem. 2003 Nov 28;278(48):47922-7.
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