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| Protein General Information |
Top |
| Full Name |
SH2B adapter protein 2 (SH2B2)
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| UniProt ID |
SH2B2_HUMAN
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| Gene Name |
SH2B2
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| Gene ID |
10603
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| References |
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| REF 1 |
The association between the SH2-containing inositol polyphosphate 5-Phosphatase 2 (SHIP2) and the adaptor protein APS has an impact on biochemical properties of both partners. J Cell Physiol. 2008 Jan;214(1):260-72.
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| REF 2 |
Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. Sci Signal. 2015 Apr 28;8(374):ra40.
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| REF 3 |
APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis. Oncogene. 1999 Jan 21;18(3):759-67.
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