Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | Retinoic acid receptor RXR-beta (RXRB) | Successful | Target Info | ||
| UniProt ID | RXRB_HUMAN | ||||
| Gene Name | RXRB | ||||
| Gene ID | 6257 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Successful Target(s) | Peroxisome proliferator-activated receptor gamma (PPAR-gamma) | Target Info | PPI Info | [1] | |
| Retinoic acid receptor gamma (RARG) | Target Info | PPI Info | [2] | ||
| Retinoic acid receptor beta (RARB) | Target Info | PPI Info | [3] | ||
| Interacting Clinical trial Target(s) | Retinoic acid receptor alpha (RARA) | Target Info | PPI Info | [2] | |
| Peroxisome proliferator-activated receptor delta (PPARD) | Target Info | PPI Info | [4] | ||
| Oxysterols receptor LXR-beta (NR1H2) | Target Info | PPI Info | [5] | ||
| Interacting Patented-recorded Target(s) | Oxysterols receptor LXR-alpha (NR1H3) | Target Info | PPI Info | [6] | |
| Interacting Literature-reported Target(s) | Pregnane X receptor (NR1I2) | Target Info | PPI Info | [7] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Mol Syst Biol. 2015 Jan 21;11(1):775. | ||||
| REF 2 | Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509. | ||||
| REF 3 | A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226. | ||||
| REF 4 | Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. Mol Cell Proteomics. 2005 Feb;4(2):205-13. | ||||
| REF 5 | Identification of a novel DNA binding site for nuclear orphan receptor OR1. J Biol Chem. 1999 Apr 9;274(15):10421-9. | ||||
| REF 6 | Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell. 2016 Feb 11;164(4):805-17. | ||||
| REF 7 | Tumor suppressor protein p53 negatively regulates human pregnane X receptor activity. Mol Pharmacol. 2013 Jun;83(6):1229-36. | ||||
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