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| Protein General Information |
Top |
| Full Name |
E3 ubiquitin-protein ligase RNF31 (RNF31)
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| UniProt ID |
RNF31_HUMAN
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| Gene Name |
RNF31
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| Gene ID |
55072
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| Interacting TTD Target Information |
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| Interacting Successful Target(s) |
Tumor necrosis factor (TNF) |
Target Info
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PPI Info
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[1] |
| Interacting Patented-recorded Target(s) |
Polyubiquitin-C (UBC) |
Target Info
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PPI Info
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[1] |
| Interacting Literature-reported Target(s) |
Linear ubiquitin chain assembly complex (RBCK1) |
Target Info
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PPI Info
|
[2] |
| References |
Top |
| REF 1 |
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol Cell. 2009 Dec 11;36(5):831-44.
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| REF 2 |
The hepatitis C virus protein NS3 suppresses TNF--stimulated activation of NF-B by targeting LUBAC. Sci Signal. 2015 Nov 17;8(403):ra118.
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