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Protein General Information (TTD Target) |
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Full Name |
Nuclear factor NF-kappa-B (NFKB2)
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Successful
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Target Info
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UniProt ID |
NFKB2_HUMAN
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Gene Name |
NFKB2
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Gene ID |
4791
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References |
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REF 1 |
Stat3 activation of NF-{kappa}B p100 processing involves CBP/p300-mediated acetylation. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7264-9.
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REF 2 |
Fbxw7- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma. Nat Cell Biol. 2012 Mar 4;14(4):375-85.
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REF 3 |
A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Nat Cell Biol. 2004 Feb;6(2):97-105.
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REF 4 |
NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B-like molecule. Mol Cell Biol. 1993 Oct;13(10):6089-101.
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