Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | Interferon regulatory factor 1 (IRF1) | Literature-reported | Target Info | ||
| UniProt ID | IRF1_HUMAN | ||||
| Gene Name | IRF1 | ||||
| Gene ID | 3659 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Clinical trial Target(s) | Ubiquitin-protein ligase E3 Mdm2 (MDM2) | Target Info | PPI Info | [1] | |
| Histone acetyltransferase p300 (EP300) | Target Info | PPI Info | [3] | ||
| Interacting Literature-reported Target(s) | Histone acetyltransferase KAT2B (KAT2B) | Target Info | PPI Info | [2] | |
| Interferon consensus sequence binding protein (IRF8) | Target Info | PPI Info | [4] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Fungal engagement of the C-type lectin mincle suppresses dectin-1-induced antifungal immunity. Cell Host Microbe. 2014 Apr 9;15(4):494-505. | ||||
| REF 2 | p300, but not PCAF, collaborates with IRF-1 in stimulating TRIM22 expression independently of its histone acetyltransferase activity. Eur J Immunol. 2013 Aug;43(8):2174-84. | ||||
| REF 3 | Regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation. J Immunol. 2003 Dec 15;171(12):6581-8. | ||||
| REF 4 | Functional domain analysis of interferon consensus sequence binding protein (ICSBP) and its association with interferon regulatory factors. J Biol Chem. 1995 Jun 2;270(22):13063-9. | ||||
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