Content Navigation
( All
None )
| Target General Information |
Top |
| Target ID |
T04599 |
Target Info
|
| Target Name |
Interferon consensus sequence binding protein (IRF8) |
| Synonyms |
Interferon regulatory factor 8; Interferon consensus sequence-binding protein; IRF-8; ICSBP1; ICSBP; H-ICSBP |
| Target Type |
Literature-reported Target |
| Gene Name |
IRF8 |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| COP9 signalosomes |
[+] 1 COP9 signalosomes |
+ |
| Interacting Protein Name |
COP9 signalosome complex subunit 2 (COPS2) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
ALIEN; CSN2; SGN2; TRIP15 |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-Western |
[2] |
| 3 |
Yeast two hybrid |
[2] |
| Transcription regulators |
[+] 1 Transcription regulators |
+ |
| Interacting Target Name |
Interferon regulatory factor 1 (IRF1) |
Literature-reported Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
IRF-1 |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-Western |
[3] |
| 2 |
Yeast two hybrid |
[4] |
| References |
Top |
| REF 1 |
Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. Immunity. 2011 Sep 23;35(3):426-40.
|
| REF 2 |
Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15). A possible link between interferon regulatory factor signaling and the COP9/signalosome. J Biol Chem. 2000 Dec 15;275(50):39081-9.
|
| REF 3 |
Functional domain analysis of interferon consensus sequence binding protein (ICSBP) and its association with interferon regulatory factors. J Biol Chem. 1995 Jun 2;270(22):13063-9.
|
| REF 4 |
Functional domains of interferon regulatory factor I (IRF-1). Biochem J. 1998 Oct 1;335 ( Pt 1):147-57.
|
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.
