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| Protein General Information |
Top |
| Full Name |
Bcl-2-binding component 3 (BBC3)
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| UniProt ID |
BBC3B_HUMAN
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| Gene Name |
BBC3
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| Gene ID |
27113
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| Interacting TTD Target Information |
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| Interacting Successful Target(s) |
Apoptosis regulator Bcl-2 (BCL-2) |
Target Info
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PPI Info
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[1] |
| Interacting Clinical trial Target(s) |
Apoptosis regulator Bcl-xL (BCL-xL) |
Target Info
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PPI Info
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[2] |
| Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) |
Target Info
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PPI Info
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[2] |
| References |
Top |
| REF 1 |
PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell. 2001 Mar;7(3):683-94.
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| REF 2 |
Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells. Cancer Res. 2017 May 1;77(9):2512-2521.
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