| Target and Pathway |
Top |
| Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
|
Inhibitor |
[2] |
| Fibroblast growth factor receptor 1 (FGFR1) |
Target Info
|
Inhibitor |
[2] |
| LCK tyrosine protein kinase (LCK) |
Target Info
|
Inhibitor |
[2] |
| Platelet-derived growth factor receptor alpha (PDGFRA) |
Target Info
|
Inhibitor |
[2] |
| Platelet-derived growth factor receptor beta (PDGFRB) |
Target Info
|
Inhibitor |
[2] |
| Proto-oncogene c-Src (SRC) |
Target Info
|
Inhibitor |
[1] |
| Stress-activated protein kinase 2a (p38 alpha) |
Target Info
|
Inhibitor |
[1] |
| Tyrosine-protein kinase ABL1 (ABL) |
Target Info
|
Inhibitor |
[1] |
| Tyrosine-protein kinase Kit (KIT) |
Target Info
|
Inhibitor |
[1] |
|
KEGG Pathway
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Ras signaling pathway
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Rap1 signaling pathway
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Cytokine-cytokine receptor interaction
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Endocytosis
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PI3K-Akt signaling pathway
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Hematopoietic cell lineage
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Melanogenesis
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Pathways in cancer
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Acute myeloid leukemia
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Central carbon metabolism in cancer
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MAPK signaling pathway
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Calcium signaling pathway
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Focal adhesion
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Gap junction
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Regulation of actin cytoskeleton
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HTLV-I infection
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MicroRNAs in cancer
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Glioma
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Prostate cancer
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Melanoma
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Choline metabolism in cancer
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ErbB signaling pathway
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Chemokine signaling pathway
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VEGF signaling pathway
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Adherens junction
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Tight junction
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Platelet activation
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GABAergic synapse
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Inflammatory mediator regulation of TRP channels
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GnRH signaling pathway
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Estrogen signaling pathway
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Prolactin signaling pathway
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Thyroid hormone signaling pathway
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Oxytocin signaling pathway
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Bacterial invasion of epithelial cells
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Epithelial cell signaling in Helicobacter pylori infection
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Shigellosis
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Tuberculosis
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Hepatitis B
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Viral carcinogenesis
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Proteoglycans in cancer
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Cell cycle
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Axon guidance
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Neurotrophin signaling pathway
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Pathogenic Escherichia coli infection
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Chronic myeloid leukemia
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Viral myocarditis
|
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FoxO signaling pathway
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Sphingolipid signaling pathway
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Adrenergic signaling in cardiomyocytes
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Osteoclast differentiation
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Signaling pathways regulating pluripotency of stem cells
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Toll-like receptor signaling pathway
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NOD-like receptor signaling pathway
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RIG-I-like receptor signaling pathway
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T cell receptor signaling pathway
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Fc epsilon RI signaling pathway
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TNF signaling pathway
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Leukocyte transendothelial migration
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Retrograde endocannabinoid signaling
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Dopaminergic synapse
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Progesterone-mediated oocyte maturation
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Amyotrophic lateral sclerosis (ALS)
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Salmonella infection
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Pertussis
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Leishmaniasis
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Chagas disease (American trypanosomiasis)
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Toxoplasmosis
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Hepatitis C
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Influenza A
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Epstein-Barr virus infection
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NF-kappa B signaling pathway
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Natural killer cell mediated cytotoxicity
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Primary immunodeficiency
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HIF-1 signaling pathway
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Dorso-ventral axis formation
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Pancreatic cancer
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Endometrial cancer
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Bladder cancer
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Non-small cell lung cancer
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NetPath Pathway
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IL3 Signaling Pathway
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IL4 Signaling Pathway
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KitReceptor Signaling Pathway
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TGF_beta_Receptor Signaling Pathway
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IL2 Signaling Pathway
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IL5 Signaling Pathway
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FSH Signaling Pathway
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TCR Signaling Pathway
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EGFR1 Signaling Pathway
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Panther Pathway
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Angiogenesis
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PDGF signaling pathway
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Cadherin signaling pathway
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Integrin signalling pathway
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Parkinson disease
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CCKR signaling map ST
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Axon guidance mediated by Slit/Robo
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Alzheimer disease-amyloid secretase pathway
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B cell activation
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EGF receptor signaling pathway
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FGF signaling pathway
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Interferon-gamma signaling pathway
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Oxidative stress response
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TGF-beta signaling pathway
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Toll receptor signaling pathway
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VEGF signaling pathway
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Ras Pathway
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p53 pathway feedback loops 2
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p38 MAPK pathway
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T cell activation
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Pathwhiz Pathway
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Fc Epsilon Receptor I Signaling in Mast Cells
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Pathway Interaction Database
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C-MYB transcription factor network
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Signaling events mediated by Stem cell factor receptor (c-Kit)
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ATF-2 transcription factor network
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PDGFR-alpha signaling pathway
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PDGF receptor signaling network
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Endothelins
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Signaling events mediated by PRL
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LPA receptor mediated events
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Atypical NF-kappaB pathway
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Glypican 1 network
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Plasma membrane estrogen receptor signaling
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Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
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Signaling events mediated by PTP1B
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S1P3 pathway
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EPHB forward signaling
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Nectin adhesion pathway
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Regulation of p38-alpha and p38-beta
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CDC42 signaling events
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Signaling events regulated by Ret tyrosine kinase
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Arf6 signaling events
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Signaling events mediated by TCPTP
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FAS (CD95) signaling pathway
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Thromboxane A2 receptor signaling
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Netrin-mediated signaling events
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Alpha9 beta1 integrin signaling events
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CXCR4-mediated signaling events
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EGF receptor (ErbB1) signaling pathway
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Class I PI3K signaling events
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Posttranslational regulation of adherens junction stability and dissassembly
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Regulation of Androgen receptor activity
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E-cadherin signaling in the nascent adherens junction
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amb2 Integrin signaling
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Integrins in angiogenesis
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ErbB1 downstream signaling
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Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
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ErbB2/ErbB3 signaling events
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EPHA forward signaling
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E-cadherin signaling in keratinocytes
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PDGFR-beta signaling pathway
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Nongenotropic Androgen signaling
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Internalization of ErbB1
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CXCR3-mediated signaling events
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Signaling events mediated by VEGFR1 and VEGFR2
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Syndecan-2-mediated signaling events
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Class I PI3K signaling events mediated by Akt
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Syndecan-3-mediated signaling events
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Ephrin B reverse signaling
|
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Trk receptor signaling mediated by PI3K and PLC-gamma
|
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EPHA2 forward signaling
|
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Alpha-synuclein signaling
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FGF signaling pathway
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Alpha4 beta1 integrin signaling events
|
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Signaling events mediated by focal adhesion kinase
|
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p73 transcription factor network
|
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ATM pathway
|
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Regulation of Telomerase
|
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Lissencephaly gene (LIS1) in neuronal migration and development
|
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Neurotrophic factor-mediated Trk receptor signaling
|
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Validated transcriptional targets of TAp63 isoforms
|
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p53 pathway
|
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Regulation of retinoblastoma protein
|
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BCR signaling pathway
|
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p38 MAPK signaling pathway
|
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IL4-mediated signaling events
|
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CD40/CD40L signaling
|
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IL12-mediated signaling events
|
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Angiopoietin receptor Tie2-mediated signaling
|
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Role of Calcineurin-dependent NFAT signaling in lymphocytes
|
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Glucocorticoid receptor regulatory network
|
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IL2-mediated signaling events
|
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Rapid glucocorticoid signaling
|
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IL6-mediated signaling events
|
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p38 signaling mediated by MAPKAP kinases
|
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Retinoic acid receptors-mediated signaling
|
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Signaling mediated by p38-alpha and p38-beta
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EPO signaling pathway
|
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S1P2 pathway
|
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Trk receptor signaling mediated by the MAPK pathway
|
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VEGFR3 signaling in lymphatic endothelium
|
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RAC1 signaling pathway
|
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TCR signaling in naï
|
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TCR signaling in naï
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SHP2 signaling
|
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IL2 signaling events mediated by PI3K
|
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IL2 signaling events mediated by STAT5
|
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Syndecan-4-mediated signaling events
|
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N-cadherin signaling events
|
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Beta3 integrin cell surface interactions
|
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S1P1 pathway
|
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Validated targets of C-MYC transcriptional repression
|
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EGFR-dependent Endothelin signaling events
|
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Direct p53 effectors
|
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ErbB receptor signaling network
|
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Stabilization and expansion of the E-cadherin adherens junction
|
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a6b1 and a6b4 Integrin signaling
|
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Reactome
|
PIP3 activates AKT signaling
|
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Regulation of KIT signaling
|
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Constitutive Signaling by Aberrant PI3K in Cancer
|
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RAF/MAP kinase cascade
|
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Regulation of actin dynamics for phagocytic cup formation
|
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CDO in myogenesis
|
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RHO GTPases Activate WASPs and WAVEs
|
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HDR through Single Strand Annealing (SSA)
|
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Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
|
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Factors involved in megakaryocyte development and platelet production
|
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NOD1/2 Signaling Pathway
|
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p38MAPK events
|
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ERK/MAPK targets
|
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Activation of PPARGC1A (PGC-1alpha) by phosphorylation
|
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Oxidative Stress Induced Senescence
|
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DSCAM interactions
|
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ADP signalling through P2Y purinoceptor 1
|
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Platelet sensitization by LDL
|
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VEGFA-VEGFR2 Pathway
|
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activated TAK1 mediates p38 MAPK activation
|
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Activation of the AP-1 family of transcription factors
|
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KSRP (KHSRP) binds and destabilizes mRNA
|
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GPVI-mediated activation cascade
|
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Phosphorylation of CD3 and TCR zeta chains
|
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Translocation of ZAP-70 to Immunological synapse
|
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Generation of second messenger molecules
|
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PECAM1 interactions
|
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DAP12 signaling
|
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CD28 co-stimulation
|
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CD28 dependent PI3K/Akt signaling
|
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CD28 dependent Vav1 pathway
|
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CTLA4 inhibitory signaling
|
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PD-1 signaling
|
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Interleukin-2 signaling
|
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Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants
|
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SHC1 events in ERBB2 signaling
|
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PLCG1 events in ERBB2 signaling
|
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GRB2 events in EGFR signaling
|
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GAB1 signalosome
|
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SHC1 events in EGFR signaling
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EGFR downregulation
|
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GRB2 events in ERBB2 signaling
|
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PI3K events in ERBB2 signaling
|
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EGFR Transactivation by Gastrin
|
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Constitutive Signaling by EGFRvIII
|
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WikiPathways
|
Kit receptor signaling pathway
|
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Differentiation Pathway
|
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Signaling by SCF-KIT
|
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PIP3 activates AKT signaling
|
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Cardiac Progenitor Differentiation
|
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miR-targeted genes in muscle cell - TarBase
|
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miR-targeted genes in lymphocytes - TarBase
|
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miR-targeted genes in epithelium - TarBase
|
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Regulation of Actin Cytoskeleton
|
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Osteoblast Signaling
|
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Focal Adhesion
|
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Hair Follicle Development: Organogenesis (Part 2 of 3)
|
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Integrated Pancreatic Cancer Pathway
|
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Allograft Rejection
|
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Signaling Pathways in Glioblastoma
|
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Signaling by PDGF
|
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Angiogenesis
|
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ErbB Signaling Pathway
|
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Senescence and Autophagy in Cancer
|
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Notch Signaling Pathway
|
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EPO Receptor Signaling
|
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EGF/EGFR Signaling Pathway
|
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TGF beta Signaling Pathway
|
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Signaling of Hepatocyte Growth Factor Receptor
|
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Pregnane X Receptor pathway
|
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Aryl Hydrocarbon Receptor Pathway
|
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IL-3 Signaling Pathway
|
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Nanoparticle-mediated activation of receptor signaling
|
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Polycystic Kidney Disease Pathway
|
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Alpha 6 Beta 4 signaling pathway
|
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BDNF signaling pathway
|
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Oncostatin M Signaling Pathway
|
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Interleukin-11 Signaling Pathway
|
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AGE/RAGE pathway
|
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TSLP Signaling Pathway
|
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Arylhydrocarbon receptor (AhR) signaling pathway
|
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Regulation of Microtubule Cytoskeleton
|
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FSH signaling pathway
|
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Leptin signaling pathway
|
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RANKL/RANK Signaling Pathway
|
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Integrin-mediated Cell Adhesion
|
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Androgen receptor signaling pathway
|
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Apoptosis-related network due to altered Notch3 in ovarian cancer
|
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Fcgamma receptor (FCGR) dependent phagocytosis
|
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ATM Signaling Pathway
|
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Retinoblastoma (RB) in Cancer
|
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Pathogenic Escherichia coli infection
|
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Integrated Breast Cancer Pathway
|
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Signaling by Robo receptor
|
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Myogenesis
|
|
Factors involved in megakaryocyte development and platelet production
|
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Toll-like receptor signaling pathway
|
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Monoamine Transport
|
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Serotonin HTR1 Group and FOS Pathway
|
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TCR Signaling Pathway
|
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Interferon type I signaling pathways
|
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Insulin Signaling
|
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MAPK Cascade
|
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Oxidative Stress
|
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p38 MAPK Signaling Pathway
|
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IL-4 Signaling Pathway
|
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MAPK Signaling Pathway
|
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Cardiac Hypertrophic Response
|
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MAP kinase activation in TLR cascade
|
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Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
|
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Structural Pathway of Interleukin 1 (IL-1)
|
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JAK/STAT
|
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Amyotrophic lateral sclerosis (ALS)
|
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Parkinsons Disease Pathway
|
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Corticotropin-releasing hormone
|
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B Cell Receptor Signaling Pathway
|
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Prostate Cancer
|
|
TWEAK Signaling Pathway
|
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miR-targeted genes in leukocytes - TarBase
|
|
IL-1 signaling pathway
|
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Signal amplification
|
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Platelet homeostasis
|
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NGF signalling via TRKA from the plasma membrane
|
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DSCAM interactions
|
|
MicroRNAs in cardiomyocyte hypertrophy
|
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Physiological and Pathological Hypertrophy of the Heart
|
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Regulation of toll-like receptor signaling pathway
|
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IL-2 Signaling Pathway
|
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Inflammatory Response Pathway
|
|
DAP12 interactions
|
|
Host Interactions of HIV factors
|
|
T-Cell Receptor and Co-stimulatory Signaling
|
|
TCR signaling
|
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Costimulation by the CD28 family
|
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Endochondral Ossification
|
|
Mesodermal Commitment Pathway
|
|
Hair Follicle Development: Induction (Part 1 of 3)
|
|
Neural Crest Differentiation
|
|
Signaling by FGFR
|
|
PDGF Pathway
|
|
Extracellular vesicle-mediated signaling in recipient cells
|
|
TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer
|
|
Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
|
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Bladder Cancer
|
|
Signaling by ERBB4
|
|
Signaling by ERBB2
|
|
Gastrin-CREB signalling pathway via PKC and MAPK
|
|
Aryl Hydrocarbon Receptor
|
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Spinal Cord Injury
|
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Gastric cancer network 2
|
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Signaling by EGFR
|
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L1CAM interactions
|
