Drug General Information
Drug ID	D0PZ4Y
Former ID	DIB005802
Drug Name	PF-3557156
Synonyms	PDE 7 inhibitor (pain), Pfizer; Phosphodiesterase 7 inhibitor (pain), Pfizer
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Discontinued in Phase 1	[548590]
Company	Pfizer Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	[C@H]1(C[C@H](C1)Oc1ccc(c2c1C1(CCCCC1)NC(=O)N2)Cl)C(=O)<br />O
Target and Pathway
Target(s)	Phosphodiesterase (PDE) 7B	Target Info	Modulator
	Phosphodiesterase (PDE) 7A	Target Info	Modulator
KEGG Pathway	Purine metabolism
	Morphine addictionhsa00230:Purine metabolism
	Morphine addiction
NetPath Pathway	EGFR1 Signaling Pathway
	TCR Signaling Pathway
	IL2 Signaling Pathway
Reactome	G alpha (s) signalling eventsR-HSA-418555:G alpha (s) signalling events
WikiPathways	G Protein Signaling PathwaysWP35:G Protein Signaling Pathways
	Ectoderm Differentiation
References
Ref 548590	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800026842)

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