| Drug General Information |
| Drug ID |
D0SD9H
|
| Former ID |
DNC002447
|
| Drug Name |
Beta-D-Mannose
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C6H12O6
|
| Canonical SMILES |
C(C1C(C(C(C(O1)O)O)O)O)O
|
| InChI |
1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6-/m1/s1
|
| InChIKey |
WQZGKKKJIJFFOK-RWOPYEJCSA-N
|
| CAS Number |
CAS 7322-31-8
|
| PubChem Compound ID |
|
| PubChem Substance ID |
5277, 583700, 583878, 583889, 583936, 583941, 583999, 584279, 584576, 584807, 584832, 584841, 585283, 585734, 585737, 585787, 585809, 585889, 585895, 819766, 819771, 819824, 819827, 819863, 819964, 819966, 819980, 819986, 820048, 820185, 820289, 820399, 820435, 820698, 820903, 820936, 821110, 821115, 821117, 821136, 821331, 821403, 821409, 821412, 821416, 821420, 821423, 821628, 821701, 821773
|
| Target and Pathway |
| Target(s) |
Cholinesterase |
Target Info |
Inhibitor |
[1]
|
|---|
| Carbonic anhydrase XIV |
Target Info |
Inhibitor |
[1]
|
| Prostaglandin G/H synthase 1 |
Target Info |
Inhibitor |
[1]
|
| Rhodopsin |
Target Info |
Inhibitor |
[1]
|
| Neuraminidase |
Target Info |
Inhibitor |
[1]
|
|
BioCyc Pathway
|
C20 prostanoid biosynthesis
|
|
KEGG Pathway
|
Nitrogen metabolismhsa00590:Arachidonic acid metabolism
|
|
Metabolic pathways
|
|
Platelet activation
|
|
Serotonergic synapsehsa04744:Phototransductionstm00511:Other glycan degradation
|
|
NetPath Pathway
|
TGF_beta_Receptor Signaling Pathway
|
|
PANTHER Pathway
|
Muscarinic acetylcholine receptor 1 and 3 signaling pathway
|
|
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
|
|
Nicotinic acetylcholine receptor signaling pathwayP00031:Inflammation mediated by chemokine and cytokine signaling pathwayP00028:Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction
|
|
Pathway Interaction Database
|
Visual signal transduction: Rods
|
|
PathWhiz Pathway
|
Arachidonic Acid Metabolism
|
|
Reactome
|
Reversible hydration of carbon dioxideR-HSA-2453902:The canonical retinoid cycle in rods (twilight vision)
|
|
Inactivation, recovery and regulation of the phototransduction cascade
|
|
G alpha (i) signalling events
|
|
WikiPathways
|
Irinotecan PathwayWP2770:Reversible Hydration of Carbon DioxideWP98:Prostaglandin Synthesis and Regulation
|
|
Arachidonic acid metabolism
|
|
Phase 1 - Functionalization of compounds
|
|
Eicosanoid Synthesis
|
|
Selenium Micronutrient NetworkWP455:GPCRs, Class A Rhodopsin-like
|
|
Visual phototransduction
|
|
Regulation of Microtubule Cytoskeleton
|
|
Integrated Breast Cancer Pathway
|
|
Integrin-mediated Cell Adhesion
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
