| Drug General Information |
| Drug ID |
D0P7JE
|
| Former ID |
DNC002604
|
| Drug Name |
S,S-(2-Hydroxyethyl)Thiocysteine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C5H10NO3S2-
|
| Canonical SMILES |
C(CSSCC(C(=O)[O-])N)O
|
| InChI |
1S/C5H11NO3S2/c6-4(5(8)9)3-11-10-2-1-7/h4,7H,1-3,6H2,(H,8,9)/p-1/t4-/m0/s1
|
| InChIKey |
YPUBRSXDQSFQBA-BYPYZUCNSA-M
|
| PubChem Compound ID |
|
| PubChem Substance ID |
|
| Target and Pathway |
| Target(s) |
Thymidylate synthase |
Target Info |
Inhibitor |
[1]
|
|---|
| DTDP-4-dehydrorhamnose 3,5-epimerase rmlC |
Target Info |
Inhibitor |
[1]
|
| CAMP-specific 3',5'-cyclic phosphodiesterase 4B |
Target Info |
Inhibitor |
[1]
|
| Maspin |
Target Info |
Inhibitor |
[1]
|
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1 |
Target Info |
Inhibitor |
[1]
|
| Delta-aminolevulinic acid dehydratase |
Target Info |
Inhibitor |
[1]
|
|
BioCyc Pathway
|
Pyrimidine deoxyribonucleotides biosynthesis from CTP
|
|
Pyrimidine deoxyribonucleotides de novo biosynthesis
|
|
Superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
|
|
Superpathway of pyrimidine deoxyribonucleoside salvage
|
|
DTMP de novo biosynthesis (mitochondrial)
|
|
Pyrimidine deoxyribonucleosides salvagePWY-5920:Heme biosynthesis
|
|
Tetrapyrrole biosynthesis
|
|
KEGG Pathway
|
Pyrimidine metabolism
|
|
One carbon pool by folate
|
|
Metabolic pathwayshsa00230:Purine metabolism
|
|
cAMP signaling pathway
|
|
Morphine addictionhsa04115:p53 signaling pathway
|
|
MicroRNAs in cancerhsa00860:Porphyrin and chlorophyll metabolism
|
|
Metabolic pathways
|
|
NetPath Pathway
|
IL5 Signaling Pathway
|
|
IL2 Signaling Pathway
|
|
PANTHER Pathway
|
De novo pyrimidine deoxyribonucleotide biosynthesis
|
|
Formyltetrahydroformate biosynthesisP00059:p53 pathwayP02746:Heme biosynthesis
|
|
Pathway Interaction Database
|
E2F transcription factor networkp53downstreampathway:Direct p53 effectors
|
|
ATF-2 transcription factor network
|
|
Validated transcriptional targets of TAp63 isoforms
|
|
PathWhiz Pathway
|
Pyrimidine MetabolismPW000158:Porphyrin Metabolism
|
|
Reactome
|
E2F mediated regulation of DNA replication
|
|
Pyrimidine biosynthesis
|
|
G1/S-Specific TranscriptionR-HSA-180024:DARPP-32 events
|
|
G alpha (s) signalling events
|
|
WikiPathways
|
Trans-sulfuration and one carbon metabolism
|
|
Retinoblastoma (RB) in Cancer
|
|
One Carbon Metabolism
|
|
Integrated Pancreatic Cancer Pathway
|
|
miR-targeted genes in muscle cell - TarBase
|
|
miR-targeted genes in lymphocytes - TarBase
|
|
miR-targeted genes in leukocytes - TarBase
|
|
miR-targeted genes in epithelium - TarBase
|
|
Metabolism of nucleotides
|
|
Fluoropyrimidine ActivityWP35:G Protein Signaling Pathways
|
|
Myometrial Relaxation and Contraction Pathways
|
|
Nuclear Receptors Meta-Pathway
|
|
Opioid SignallingWP561:Heme Biosynthesis
|
|
Metabolism of porphyrins
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
