| Drug General Information |
| Drug ID |
D03AAP
|
| Former ID |
DNC002712
|
| Drug Name |
Isopropyl Alcohol
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C3H8O
|
| Canonical SMILES |
CC(C)O
|
| InChI |
1S/C3H8O/c1-3(2)4/h3-4H,1-2H3
|
| InChIKey |
KFZMGEQAYNKOFK-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
4963, 423976, 589444, 813293, 823371, 825349, 826612, 841342, 3135164, 5272310, 6436218, 7847205, 7888433, 7888444, 8006213, 8006303, 8006343, 8006719, 8007054, 8007624, 8007625, 8008177, 8008179, 8008181, 8008185, 8008188, 8008189, 8008222, 8008715, 8008832, 8009929, 8009948, 8010226, 8011055, 8011235, 8011519, 8011800, 8012365, 8013746, 8013748, 8013757, 8014331, 8014403, 8014510, 8014698, 8015403, 8015571, 8016872, 8018534, 8019056
|
| SuperDrug ATC ID |
D08AX05
|
| Target and Pathway |
| Target(s) |
GTP cyclohydrolase I |
Target Info |
Inhibitor |
[1]
|
|---|
| Phospholipase A2, membrane associated |
Target Info |
Inhibitor |
[1]
|
| Tumor necrosis factor |
Target Info |
Inhibitor |
[1]
|
| Adenosylhomocysteinase |
Target Info |
Inhibitor |
[1]
|
|
BioCyc Pathway
|
PhospholipasesPWY-5328:Superpathway of methionine degradation
|
|
Methionine degradation
|
|
Cysteine biosynthesis
|
|
KEGG Pathway
|
Glycerophospholipid metabolism
|
|
Ether lipid metabolism
|
|
Arachidonic acid metabolism
|
|
Linoleic acid metabolism
|
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alpha-Linolenic acid metabolism
|
|
Metabolic pathways
|
|
Ras signaling pathway
|
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Vascular smooth muscle contraction
|
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Pancreatic secretion
|
|
Fat digestion and absorptionhsa04010:MAPK signaling pathway
|
|
Cytokine-cytokine receptor interaction
|
|
NF-kappa B signaling pathway
|
|
Sphingolipid signaling pathway
|
|
mTOR signaling pathway
|
|
Apoptosis
|
|
TGF-beta signaling pathway
|
|
Osteoclast differentiation
|
|
Antigen processing and presentation
|
|
Toll-like receptor signaling pathway
|
|
NOD-like receptor signaling pathway
|
|
RIG-I-like receptor signaling pathway
|
|
Hematopoietic cell lineage
|
|
Natural killer cell mediated cytotoxicity
|
|
T cell receptor signaling pathway
|
|
Fc epsilon RI signaling pathway
|
|
TNF signaling pathway
|
|
Adipocytokine signaling pathway
|
|
Type II diabetes mellitus
|
|
Non-alcoholic fatty liver disease (NAFLD)
|
|
Type I diabetes mellitus
|
|
Alzheimer's disease
|
|
Amyotrophic lateral sclerosis (ALS)
|
|
Pertussis
|
|
Legionellosis
|
|
Leishmaniasis
|
|
Chagas disease (American trypanosomiasis)
|
|
African trypanosomiasis
|
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Malaria
|
|
Toxoplasmosis
|
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Amoebiasis
|
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Tuberculosis
|
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Hepatitis C
|
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Hepatitis B
|
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Influenza A
|
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HTLV-I infection
|
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Herpes simplex infection
|
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Proteoglycans in cancer
|
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Asthma
|
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Inflammatory bowel disease (IBD)
|
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Systemic lupus erythematosus
|
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Rheumatoid arthritis
|
|
Allograft rejection
|
|
Graft-versus-host disease
|
|
Hypertrophic cardiomyopathy (HCM)
|
|
Dilated cardiomyopathyhsa00270:Cysteine and methionine metabolism
|
|
NetPath Pathway
|
TCR Signaling Pathway
|
|
IL2 Signaling Pathway
|
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IL3 Signaling Pathway
|
|
IL4 Signaling Pathway
|
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Leptin Signaling Pathway
|
|
RANKL Signaling Pathway
|
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IL1 Signaling Pathway
|
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PANTHER Pathway
|
Apoptosis signaling pathway
|
|
Wnt signaling pathway
|
|
Pathway Interaction Database
|
Glypican 1 networkil27pathway:IL27-mediated signaling events
|
|
Canonical NF-kappaB pathway
|
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
|
|
Angiopoietin receptor Tie2-mediated signaling
|
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Signaling events mediated by HDAC Class I
|
|
TNF receptor signaling pathway
|
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Ceramide signaling pathway
|
|
amb2 Integrin signaling
|
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RXR and RAR heterodimerization with other nuclear receptor
|
|
IL23-mediated signaling events
|
|
HIV-1 Nef: Negative effector of Fas and TNF-alpha
|
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Caspase Cascade in Apoptosis
|
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Cellular roles of Anthrax toxin
|
|
Downstream signaling in naï
|
|
PathWhiz Pathway
|
Pterine BiosynthesisPW000453:Fc Epsilon Receptor I Signaling in Mast CellsPW000007:Selenoamino Acid Metabolism
|
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Betaine Metabolism
|
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Methionine Metabolism
|
|
Reactome
|
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulationR-HSA-1482788:Acyl chain remodelling of PC
|
|
Acyl chain remodelling of PE
|
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Acyl chain remodelling of PIR-HSA-381340:Transcriptional regulation of white adipocyte differentiation
|
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TNFR1-induced proapoptotic signaling
|
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Regulation of TNFR1 signaling
|
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TNFR1-induced NFkappaB signaling pathway
|
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TNFR1-mediated ceramide production
|
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TNFR2 non-canonical NF-kB pathway
|
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TNF signaling
|
|
WikiPathways
|
Cardiac Hypertrophic Response
|
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Glycerophospholipid biosynthesis
|
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Glycerophospholipid Biosynthetic Pathway
|
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Spinal Cord Injury
|
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Eicosanoid Synthesis
|
|
MicroRNAs in cardiomyocyte hypertrophyWP75:Toll-like receptor signaling pathway
|
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Monoamine Transport
|
|
SIDS Susceptibility Pathways
|
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TGF Beta Signaling Pathway
|
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Cytokines and Inflammatory Response
|
|
MAPK Signaling Pathway
|
|
EV release from cardiac cells and their functional effects
|
|
FAS pathway and Stress induction of HSP regulation
|
|
Apoptosis-related network due to altered Notch3 in ovarian cancer
|
|
Transcriptional Regulation of White Adipocyte Differentiation
|
|
Aryl Hydrocarbon Receptor
|
|
Apoptosis
|
|
Nanoparticle triggered regulated necrosis
|
|
Amyotrophic lateral sclerosis (ALS)
|
|
Adipogenesis
|
|
Allograft Rejection
|
|
TNF alpha Signaling Pathway
|
|
TWEAK Signaling Pathway
|
|
Extrinsic Pathway for Apoptosis
|
|
Folate Metabolism
|
|
MicroRNAs in cardiomyocyte hypertrophy
|
|
Vitamin B12 Metabolism
|
|
Selenium Micronutrient Network
|
|
Regulation of toll-like receptor signaling pathway
|
|
Matrix MetalloproteinasesWP2693:Metabolism of amino acids and derivatives
|
|
Trans-sulfuration and one carbon metabolism
|
|
One Carbon Metabolism
|
|
Trans-sulfuration pathway
|
|
Phase II conjugation
|
| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
|---|
