| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T94788 | ||||
| Target Name | Branched chain amino acid-dependent aminotransferase | ||||
| Target Type | Research |
||||
| Drug Potency against Target | N'-(phenylsulfonyl)benzofuran-2-carbohydrazide | Drug Info | IC50 = 18300 nM | [527724] | |
| N'-(phenylsulfonyl)quinoline-6-carbohydrazide | Drug Info | IC50 = 13300 nM | [527724] | ||
| References | |||||
| Ref 527724 | Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. Epub 2005 Sep 6.The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases. | ||||
| Ref 527724 | Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. Epub 2005 Sep 6.The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases. | ||||
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