TTD | Drug: D0W0FI

Drug General Information
Drug ID	D0W0FI
Former ID	DNC006450
Drug Name	N'-(phenylsulfonyl)quinoline-6-carbohydrazide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527724]
Structure		Download 2D MOL 3D MOL
Formula	C16H13N3O3S
Canonical SMILES	C1=CC=C(C=C1)S(=O)(=O)NNC(=O)C2=CC3=C(C=C2)N=CC=C3
InChI	1S/C16H13N3O3S/c20-16(13-8-9-15-12(11-13)5-4-10-17-15)18-19-23(21,22)14-6-2-1-3-7-14/h1-11,19H,(H,18,20)
InChIKey	YPRPLJAGGWUKMX-UHFFFAOYSA-N
PubChem Compound ID	9967156
Target and Pathway
Target(s)	Branched chain amino acid-dependent aminotransferase	Target Info	Inhibitor	[527724]
BioCyc Pathway	Leucine degradation
	Valine degradation
	Isoleucine degradation
KEGG Pathway	Valine, leucine and isoleucine degradation
	Valine, leucine and isoleucine biosynthesis
	Pantothenate and CoA biosynthesis
	Metabolic pathways
	Biosynthesis of antibiotics
	2-Oxocarboxylic acid metabolism
	Biosynthesis of amino acids
PANTHER Pathway	Alanine biosynthesis
	Isoleucine biosynthesis
	Leucine biosynthesis
	Valine biosynthesis
WikiPathways	Metabolism of amino acids and derivatives
References
Ref 527724	Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. Epub 2005 Sep 6.The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.
Ref 527724	Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. Epub 2005 Sep 6.The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.

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Drug Information