Target Information
Target General Infomation | |||||
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Target ID |
T94788
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Former ID |
TTDR01028
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Target Name |
Branched chain amino acid-dependent aminotransferase
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Gene Name |
BCAT2
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Synonyms |
BCAT; BCAT(c); BCAT(m); Branched-chain amino acid aminotransferase; ECA39 protein; PP18; Placental protein 18; BCAT2
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Target Type |
Research
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Function |
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.
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BioChemical Class |
Transferases of nitrogenous groups
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Target Validation |
T94788
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UniProt ID | |||||
EC Number |
EC2.6.1.42
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Sequence |
MAAAALGQIWARKLLSVPWLLCGPRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKT
FTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRP WLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSL GVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLV QQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQS LLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIP TMENGPELILRFQKELKEIQYGIRAHEWMFPV |
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Pathways | |||||
BioCyc Pathway | Leucine degradation | ||||
Valine degradation | |||||
Isoleucine degradation | |||||
KEGG Pathway | Valine, leucine and isoleucine degradation | ||||
Valine, leucine and isoleucine biosynthesis | |||||
Pantothenate and CoA biosynthesis | |||||
Metabolic pathways | |||||
Biosynthesis of antibiotics | |||||
2-Oxocarboxylic acid metabolism | |||||
Biosynthesis of amino acids | |||||
PANTHER Pathway | Alanine biosynthesis | ||||
Isoleucine biosynthesis | |||||
Leucine biosynthesis | |||||
Valine biosynthesis | |||||
WikiPathways | Metabolism of amino acids and derivatives | ||||
References |
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