Drug Information

Drug General Information
Drug ID
D0AW6C
Former ID
DNC006451
Drug Name
N'-(phenylsulfonyl)benzofuran-2-carbohydrazide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527724]
Structure
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2D MOL

3D MOL
Formula
C15H12N2O4S
Canonical SMILES
C1=CC=C(C=C1)S(=O)(=O)NNC(=O)C2=CC3=CC=CC=C3O2
InChI
1S/C15H12N2O4S/c18-15(14-10-11-6-4-5-9-13(11)21-14)16-17-22(19,20)12-7-2-1-3-8-12/h1-10,17H,(H,16,18)
InChIKey
AMGAILKMHSFVNJ-UHFFFAOYSA-N
PubChem Compound ID
9879950
Target and Pathway
Target(s) Branched chain amino acid-dependent aminotransferase Target Info Inhibitor [527724]
BioCyc Pathway Leucine degradation
Valine degradation
Isoleucine degradation
KEGG Pathway Valine, leucine and isoleucine degradation
Valine, leucine and isoleucine biosynthesis
Pantothenate and CoA biosynthesis
Metabolic pathways
Biosynthesis of antibiotics
2-Oxocarboxylic acid metabolism
Biosynthesis of amino acids
PANTHER Pathway Alanine biosynthesis
Isoleucine biosynthesis
Leucine biosynthesis
Valine biosynthesis
WikiPathways Metabolism of amino acids and derivatives
References
Ref 527724Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. Epub 2005 Sep 6.The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.
Ref 527724Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. Epub 2005 Sep 6.The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.

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