Target Information
| Target General Infomation | |||||
|---|---|---|---|---|---|
| Target ID |
T94788
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| Former ID |
TTDR01028
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| Target Name |
Branched chain amino acid-dependent aminotransferase
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| Gene Name |
BCAT2
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| Synonyms |
BCAT; BCAT(c); BCAT(m); Branched-chain amino acid aminotransferase; ECA39 protein; PP18; Placental protein 18; BCAT2
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| Target Type |
Research
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| Function |
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids.
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| BioChemical Class |
Transferases of nitrogenous groups
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| Target Validation |
T94788
|
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| UniProt ID | |||||
| EC Number |
EC2.6.1.42
|
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| Sequence |
MAAAALGQIWARKLLSVPWLLCGPRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKT
FTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRP WLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSL GVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLV QQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQS LLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIP TMENGPELILRFQKELKEIQYGIRAHEWMFPV |
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| Pathways | |||||
| BioCyc Pathway | Leucine degradation | ||||
| Valine degradation | |||||
| Isoleucine degradation | |||||
| KEGG Pathway | Valine, leucine and isoleucine degradation | ||||
| Valine, leucine and isoleucine biosynthesis | |||||
| Pantothenate and CoA biosynthesis | |||||
| Metabolic pathways | |||||
| Biosynthesis of antibiotics | |||||
| 2-Oxocarboxylic acid metabolism | |||||
| Biosynthesis of amino acids | |||||
| PANTHER Pathway | Alanine biosynthesis | ||||
| Isoleucine biosynthesis | |||||
| Leucine biosynthesis | |||||
| Valine biosynthesis | |||||
| WikiPathways | Metabolism of amino acids and derivatives | ||||
| References | |||||
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