Drug General Information
Drug ID	D0V3YB
Former ID	DNC005728
Drug Name	3,4-diarylpyrazoline derivative
Indication	Discovery agent		Investigative	[527721]
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Cannabinoid receptor 1	Target Info	Inhibitor	[527721]
	Cannabinoid receptor 2	Target Info	Inhibitor	[527721]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction
PANTHER Pathway	Endogenous cannabinoid signaling
Pathway Interaction Database	N-cadherin signaling events
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors)
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Small Ligand GPCRs
	BDNF signaling pathway
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like
References
Ref 527721	Bioorg Med Chem Lett. 2005 Nov 1;15(21):4794-8.Novel 3,4-diarylpyrazolines as potent cannabinoid CB1 receptor antagonists with lower lipophilicity.
Ref 527721	Bioorg Med Chem Lett. 2005 Nov 1;15(21):4794-8.Novel 3,4-diarylpyrazolines as potent cannabinoid CB1 receptor antagonists with lower lipophilicity.

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