Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | 4-Morpholin-4-yl-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 1-(2-(4-(3-fluoro-4-(6-methylpyridin-3-yloxy)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3-yloxy)ethyl)piperidin-4-ol | Drug Info |
| EGFR3 --- HER2 | (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(naphthalen-2-yl)acrylate | Drug Info |
| EGFR3 --- HER2 | But-2-enedioic acid [4-(3-bromo-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-amide (3-diethylamino-propyl)-amide | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-pentyloxy-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | CHEMBL438536 | Drug Info |
| EGFR3 --- HER2 | 5-(Dimethyl-hydrazonomethyl)-N-[1-(3-fluoro-benzyl)-1H-indazol-5-yl]-pyrimidine-4,6-diamine | Drug Info |
| EGFR3 --- HER2 | 2-(3,5-Bis(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(1-benzyl-2,3-dihydro-1H-indol-5-ylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(thiophen-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | 4-[(3-methylphenyl)amino]-6-(methylamino)quinazoline | Drug Info |
| EGFR3 --- HER2 | 1-(2-chloroethyl)-1-nitroso-3-methyl-3-{[4-(3-methylphenyl)amino]quinazolin-6-yl}urea | Drug Info |
| EGFR3 --- HER2 | 4-(2-(3-fluorobenzyl)-1H-benzo[d]imidazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| EGFR3 --- HER2 | 4-Piperidin-1-yl-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-5-(1-piperidinyl)-2-pentynamide | Drug Info |
| EGFR3 --- HER2 | 4-(3-bromophenylamino)-6,7-bis(methoxymethoxy)quinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)thiophen-2-yl)thieno[2,3-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-(4-Methyl-piperazin-1-yl)-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 6,7-dimethoxy-4-(p-tolylamino)quinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 4-(1-(3-chlorobenzyl)-1H-indazol-5-ylamino)-6-aminopyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-4-(4-morpholinyl)-2-butynamide | Drug Info |
| EGFR3 --- HER2 | CHEMBL436511 | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Bromo-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | CHEMBL193544 | Drug Info |
| EGFR3 --- HER2 | CHEMBL255376 | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Bromo-4-fluoro-phenylamino)-7-(3-morpholin-4-yl-propoxy)-quinazolin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-fluorobenzylamino)-6-aminopyrimidine-5-carbaldehyde O-methyl oxime | Drug Info |
| EGFR3 --- HER2 | (S)-N-(3-ethynylphenyl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | (E)-ethyl 4-(3-(6-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)pyrimidin-4-yloxy)phenylamino)-4-oxobut-2-enoate | Drug Info |
| EGFR3 --- HER2 | N-{4-(3-Chloro-4-fluoro-phenylamino)-7-[3-(4-methyl-piperazin-1-yl)-propoxy]-pyrido[3,2-d]pyrimidin-6-yl}-acrylamide | Drug Info |
| EGFR3 --- HER2 | N-(4-Bromophenylsulfonyl)-2-(4-fluorophenyl)acetamide | Drug Info |
| EGFR3 --- HER2 | 1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea | Drug Info |
| EGFR3 --- HER2 | N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((2-methoxyethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(phenylaminomethyl-amino)-phenylamino]-3-cyano-7-methoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | 2-(3-(4-Bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl propionate | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(1-benzyl-3-fluoro-1H-indol-5-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | CHEMBL404405 | Drug Info |
| EGFR3 --- HER2 | 4-[3-Chloro-4-(3-fluorobenzyloxy)anilino]-6-(3-nitro phenoxy)pyrimidine | Drug Info |
| EGFR3 --- HER2 | [3-Chloro-4-(3-fluoro-benzyloxy)-phenyl]-[5-(1-methyl-piperidin-4-yloxy)-quinazolin-4-yl]-amine | Drug Info |
| EGFR3 --- HER2 | N-(4-Fluorophenylsulfonyl)-2-(2-methyl-5-nitro-1Himidazol-1-yl)acetamide | Drug Info |
| EGFR3 --- HER2 | Pentanedioic acid (2R,5R)-5-(6-amino-purin-9-yl)-3,4-diisopropoxy-tetrahydro-furan-2-ylmethyl ester 4-((E)-2-nitro-vinyl)-phenyl ester | Drug Info |
| EGFR3 --- HER2 | Lapatinib tosylate | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Chloro-4-fluoro-phenylamino)-7-(4-morpholin-4-yl-but-1-enyl)-pyrido[3,2-d]pyrimidin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | CANERTINIB DIHYDROCHLORIDE | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(naphthalen-1-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | 7-(4-(3-chloro-4-fluorophenylamino)-6-methoxyquinazolin-7-yloxy)-N-hydroxyheptanamide | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid [4-(3-chloro-4-cyclohexylmethoxy-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-5-((4-((dimethylamino)methyl)phenyl)ethynyl)-6-methylpyrimidin-4-amine | Drug Info |
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