Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| EGFR3 --- HER2 | 4-(3-bromophenylamino)-6,7-bis(2-methoxyethoxy)quinoline-3-carbonitrile | Drug Info |
| EGFR3 --- HER2 | 2-(3-Phenyl-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | (E)-2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-1-ylsulfanylmethyl)-phenyl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | SID506629 | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)furan-2-yl)thieno[2,3-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | Pentanedioic acid 3-methoxy-phenyl ester 4-((E)-2-nitro-vinyl)-phenyl ester | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(4-(pyridin-2-ylthio)phenylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((dimethylamino)methyl)furan-2-yl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-bromophenylamino)-3-cyano-7-methoxyquinolin-6-yl)but-2-ynamide | Drug Info |
| EGFR3 --- HER2 | (E)-3-(3-Benzylsulfanylmethyl-4-hydroxy-5-methoxy-phenyl)-2-cyano-acrylamide | Drug Info |
| EGFR3 --- HER2 | (R)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(pyrrolidin-2-ylethynyl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((ethylamino)methyl)-1H-pyrrol-2-yl)thieno[2,3-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-(4-Benzyloxy-3-chloro-phenyl)-5-[5-(2-morpholin-4-yl-ethyl)-[1,3,4]oxadiazol-2-yl]-pyrimidine-4,6-diamine | Drug Info |
| EGFR3 --- HER2 | 6-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyhexanamide | Drug Info |
| EGFR3 --- HER2 | 2-(2-(4-Hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | N-[4-(4-Benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-3-quinolin-8-yl-acrylamide | Drug Info |
| EGFR3 --- HER2 | 3-Methoxymethoxy-propynoic acid [4-(3-bromo-phenylamino)-3-cyano-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(5-((2-(methylsulfonyl)ethylamino)methyl)-1H-pyrrol-2-yl)thieno[3,2-d]pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | 5-((4-aminopiperidin-1-yl)methyl)-N-m-tolylpyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | 4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-3-methyl-N-(2-(4-methylpiperazin-1-yl)ethyl)-1H-pyrrolo[3,2-d]pyridazine-2-carboxamide | Drug Info |
| EGFR3 --- HER2 | 2-(3,5-Bis(4-bromophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 1-(2-(4-(3-methyl-4-(pyridin-2-ylmethoxy)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3-yloxy)ethyl)piperidin-4-ol | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-4-(diethylamino)-2-butynamide | Drug Info |
| EGFR3 --- HER2 | (3R,5S)-5-((4-(1-(thiophen-3-ylsulfonyl)-1H-indol-5-ylamino)thieno[3,2-d]pyrimidin-6-yl)ethynyl)pyrrolidin-3-yl morpholine-4-carboxylate | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Bromo-4-fluoro-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | 4-[(2-Methoxy-ethyl)-methyl-amino]-but-2-enoic acid [4-(4-benzyloxy-3-chloro-phenylamino)-3-cyano-7-ethoxy-quinolin-6-yl]-amide | Drug Info |
| EGFR3 --- HER2 | 5-(bis(2,5-dihydroxybenzyl)amino)-2-hydroxybenzoic acid | Drug Info |
| EGFR3 --- HER2 | (E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-p-tolylacrylate | Drug Info |
| EGFR3 --- HER2 | 2-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | 4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)pyrimidine-5-carbohydrazide | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-5-(4-((cyclopropylamino)methyl)styryl)-6-methylpyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | N-[4-(3-Chloro-4-fluoro-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-acrylamide | Drug Info |
| EGFR3 --- HER2 | 5-((4-aminopiperidin-1-yl)methyl)-N-(3-fluorophenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine | Drug Info |
| EGFR3 --- HER2 | 3-[4-(3-Bromo-phenylamino)-quinazolin-6-ylcarbamoyl]-acrylic acid 3-dimethylamino-propyl ester | Drug Info |
| EGFR3 --- HER2 | Yodoxin | Drug Info |
| EGFR3 --- HER2 | GW794726X | Drug Info |
| EGFR3 --- HER2 | 1-(2-(4-(3-methyl-4-(6-methylpyridin-3-yloxy)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3-yloxy)ethyl)piperidin-4-ol | Drug Info |
| EGFR3 --- HER2 | N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-5-(4-methyl-1-piperazinyl)-2-pentynamide | Drug Info |
| EGFR3 --- HER2 | TCMDC-138726 | Drug Info |
| EGFR3 --- HER2 | 2-(2-(3-Fluorobenzylidene)hydrazinyl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-methyl-5-((5-(pyrrolidin-1-ylmethyl)thiophen-2-yl)ethynyl)pyrimidin-4-amine | Drug Info |
| EGFR3 --- HER2 | SID511952 | Drug Info |
| EGFR3 --- HER2 | 1-(5-Chloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea | Drug Info |
| EGFR3 --- HER2 | N-[1-(3-Fluoro-benzyl)-1H-indazol-5-yl]-5-[(2,2,2-trifluoro-ethyl)-hydrazonomethyl]-pyrimidine-4,6-diamine | Drug Info |
| EGFR3 --- HER2 | 4-(Bis(2-chloroethyl)amino)-N-(4-chlorophenyl)benzamide | Drug Info |
| EGFR3 --- HER2 | 4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(thiazol-2-ylsulfanyl)-phenylamino]-3-cyano-7-methoxy-quinolin-6-yl}-amide | Drug Info |
| EGFR3 --- HER2 | 2-(3-(4-Methoxyphenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
| EGFR3 --- HER2 | N-(4-(3-bromophenylamino)-3-cyano-7-methoxyquinolin-6-yl)acrylamide | Drug Info |
| EGFR3 --- HER2 | 3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)-6-methylpyrimidin-5-yl)-2-fluoro-N-(2-morpholinoethyl)acrylamide | Drug Info |
| EGFR3 --- HER2 | 2-(5-(4-Bromophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one | Drug Info |
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