Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| Cathepsin K --- MEP | [(S)-1-((2S,3S)-2-tert-Butoxy-4-oxo-azetidin-3-ylcarbamoyl)-2-phenyl-ethyl]-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | (R,S)-4-methyl-2-[3'-(2-piperazin-1-yl-thiazol-4-yl)-biphenyl-3-yl]-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(cyanomethyl)-4-methyl-2-((S)-1,1,1-trifluorohexan-2-ylamino)pentanamide | Drug Info |
| Cathepsin K --- MEP | ((S)-1-Formyl-pentyl)-carbamic acid 1-benzyl-cyclohexyl ester | Drug Info |
| Cathepsin K --- MEP | 3-Chloro-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-4-methanesulfonylamino-benzamide | Drug Info |
| Cathepsin K --- MEP | 5-(3-(4,5-dichloro-1H-imidazol-1-yl)prop-1-ynyl)-4-(neopentylamino)pyrimidine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | (S)-2-(7-chlorobenzo[d]oxazol-2-ylamino)-3-cyclohexyl-N-((S)-1-(4-methoxyphenylamino)propan-2-yl)propanamide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-(4,4-dimethylcyclohexyl)-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | N-{(S)-2-(2-Chloro-phenyl)-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-ethyl}-3-methyl-benzamide | Drug Info |
| Cathepsin K --- MEP | benzyl (2S,3S)-1-(cyanomethylamino)-3-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid {2-[4-(1-methyl-piperidin-4-yloxy)-phenyl]-ethyl}-amide | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-((S)-1-(4-methoxyphenylamino)propan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 1-benzyl-cyclopentylmethyl ester | Drug Info |
| Cathepsin K --- MEP | 4-Benzenesulfonylamino-3-chloro-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-benzamide | Drug Info |
| Cathepsin K --- MEP | 1-(2-Chloro-phenyl)-1H-[1,2,4]triazole-3-carboxylic acid {1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-amide | Drug Info |
| Cathepsin K --- MEP | 4-Methoxy-N-{1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-benzamide | Drug Info |
| Cathepsin K --- MEP | (S)-2-(7-chlorobenzo[d]oxazol-2-ylamino)-3-cyclohexyl-N-((S)-1-(4-(methylsulfonyl)phenylamino)propan-2-yl)propanamide | Drug Info |
| Cathepsin K --- MEP | (S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-pentanoic acid (cyano-dicyclopropyl-methyl)-amide | Drug Info |
| Cathepsin K --- MEP | (S)-2-(7-chlorobenzo[d]oxazol-2-ylamino)-3-cyclohexyl-N-((S)-1-(5-fluoro-3,3-dimethylindolin-1-yl)propan-2-yl)propanamide | Drug Info |
| Cathepsin K --- MEP | 9-Cyclopentyl-6-{2-[3-(4-methyl-piperazin-1-yl)-propoxy]-phenylamino}-9H-purine-2-carbonitrile | Drug Info |
| Cathepsin K --- MEP | N-{(S)-1-[2-(4-Methoxy-phenylamino)-ethylcarbamoyl]-3,3-dimethyl-butyl}-3-methyl-benzamide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-(2,2-dimethyl-propylamino)-pyrimidine-5-carboxylic acid [2-(4-methoxy-phenyl)-ethyl]-amide | Drug Info |
| Cathepsin K --- MEP | Acetic acid (2S,3S)-3-((S)-2-benzyloxycarbonylamino-3-phenyl-propionylamino)-4-oxo-azetidin-2-yl ester | Drug Info |
| Cathepsin K --- MEP | 4-(4-Cyano-benzenesulfonylamino)-N-[1-(2S-ethyl-4-oxo-tetrahydro-furan-3S-ylcarbamoyl)-2S-(1-methyl-cyclopentyl)-ethyl]-benzamide | Drug Info |
| Cathepsin K --- MEP | 4-Methyl-2-(5-phenyl-pyridin-3-yl)-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | N-((S)-1-(1-(5-fluoroindolin-1-yl)-4-(methylsulfonyl)butan-2-ylamino)-4,4-dimethyl-1-oxopentan-2-yl)-3-methoxybenzamide | Drug Info |
| Cathepsin K --- MEP | N-{(S)-1-[2-(4-Methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-4-methyl-benzamide | Drug Info |
| Cathepsin K --- MEP | SID85736001 | Drug Info |
| Cathepsin K --- MEP | [2-(2,3-difluoro-4-n-propylphenyl)phenoxy]acetaldehyde | Drug Info |
| Cathepsin K --- MEP | (S)-3-tert-butyl-N-(1-(cyanomethylamino)-3-(3-(5-(hydroxymethyl)-1,3,4-oxadiazol-2-yl)phenyl)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide | Drug Info |
| Cathepsin K --- MEP | 4-Methyl-2-(3-pyridin-2-yl-phenyl)-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | N-((S)-3-cycloheptyl-1-((4S,7R)-7-methyl-3-oxo-1-(pyridin-2-ylsulfonyl)azepan-4-ylamino)-1-oxopropan-2-yl)furan-2-carboxamide | Drug Info |
| Cathepsin K --- MEP | (S)-N-(1-(2-(5-fluoroindolin-1-yl)ethylamino)-4-methyl-1-oxopentan-2-yl)-3-methylbenzamide | Drug Info |
| Cathepsin K --- MEP | (S)-3,3-dimethyl-1-(5-phenyl-1,3,4-oxadiazol-2-yl)butan-2-yl(S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | benzyl (S)-1-((S)-2-(4-tert-butoxyphenyl)-1-cyanoethylamino)-4-methyl-1-oxopentan-2-ylcarbamate | Drug Info |
| Cathepsin K --- MEP | (S)-3-Methyl-2-(naphthalene-1-sulfonylamino)-pentanoic acid [(S)-1-formyl-2-(1H-indol-2-yl)-ethyl]-amide | Drug Info |
| Cathepsin K --- MEP | 2-(cyclohexylmethyl)-N-(4-(methylsulfonyl)-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)-4-morpholino-4-oxobutanamide | Drug Info |
| Cathepsin K --- MEP | 2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid [2-(4-pyrrolin-1-ylphenyl)-ethyl]-amide | Drug Info |
| Cathepsin K --- MEP | 1H-Indole-2-carboxylic acid {(S)-1-[2-(4-methoxy-phenylamino)-ethylcarbamoyl]-3-methyl-butyl}-amide | Drug Info |
| Cathepsin K --- MEP | (S)-4-morpholino-4-oxo-2-phenyl-N-((S)-4-phenyl-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)butanamide | Drug Info |
| Cathepsin K --- MEP | (R)-4-methyl-2-[3'-(2-piperazin-1-ylmethyl-thiazol-4-yl)-biphenyl-3-yl]-pentanoic acid cyanomethyl-amide | Drug Info |
| Cathepsin K --- MEP | N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]phenylcarbamoyl}-leucyl-glycine-nitrile | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid bicyclo[2.2.1]hept-2-yl ester | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-(3-chlorophenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)cycloheptanecarboxamide | Drug Info |
| Cathepsin K --- MEP | [(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (S)-(1,2,3,4-tetrahydro-naphthalen-1-yl) ester | Drug Info |
| Cathepsin K --- MEP | {1-[4-(2-Benzyloxycarbonylamino-4-methyl-pentanoylamino)-3-oxo-azepane-1-carbonyl]-3-methyl-butyl}-carbamic acid benzyl ester | Drug Info |
| Cathepsin K --- MEP | CHEMBL563471 | Drug Info |
| Cathepsin K --- MEP | (S)-N-(3-(3-(1,3,4-oxadiazol-2-yl)phenyl)-1-(cyanomethylamino)-1-oxopropan-2-yl)benzamide | Drug Info |
| Cathepsin K --- MEP | N-(3-methyl-1-(4-(trifluoromethoxy)phenylamino)butan-2-yl)-4-morpholino-4-oxo-2-phenethylbutanamide | Drug Info |
| Cathepsin K --- MEP | 6-(4-chlorobenzyl)-7-neopentyl-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile | Drug Info |
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