Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
DX9OFK
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| Drug Name |
2-cyano-4-cyclohexylamino-pyrimidine-5-carboxylic acid [2-(4-pyrrolin-1-ylphenyl)-ethyl]-amide
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| Synonyms |
CHEMBL217930
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| Indication | Discovery agent | Investigative | [1587926] | ||
| Formula |
C24H30N6O
|
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| Canonical SMILES |
O=C(NCCc1ccc(cc1)N2CCCC2)c3cnc(nc3NC4CCCCC4)C#N
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| InChI |
InChI=1S/C24H30N6O/c25-16-22-27-17-21(23(29-22)28-19-6-2-1-3-7-19)24(31)26-13-12-18-8-10-20(11-9-18)30-14-4-5-15-30/h8-11,17,19H,1-7,12-15H2,(H,26,31)(H,27,28,29)
|
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| InChIKey |
RLZJPYQRSZCAJD-UHFFFAOYSA-N
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| Target and Pathway | |||||
| Target(s) | Cathepsin K | Target Info | [1587926] | ||
| Cathepsin L | Target Info | [1587926] | |||
| Reactome | Collagen degradation | ||||
| Degradation of the extracellular matrix | |||||
| Activation of Matrix Metalloproteinases | |||||
| Trafficking and processing of endosomal TLR | |||||
| MHC class II antigen presentationR-HSA-1236977:Endosomal/Vacuolar pathway | |||||
| Assembly of collagen fibrils and other multimeric structures | |||||
| MHC class II antigen presentation | |||||
| References | |||||
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