Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| COX2 --- 5LOX | 1-(4-aminosulfonylphenyl)-3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-5-phenyl-1H-pyrazole | Drug Info |
| COX2 --- 5LOX | 5-(4-Chloro-phenyl)-3-[3-fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)-phenoxymethyl]-pyrazole-1-sulfonic acid amide | Drug Info |
| COX2 --- 5LOX | 2-Fluoro-6-methoxy-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | N-Hydroxy-N-methyl-3-(3-phenoxy-phenyl)-acrylamide | Drug Info |
| COX2 --- 5LOX | 7-tert-butyl-3,3-dimethyl-5-(thiophen-2-ylmethyl)-2,3-dihydrobenzofuran | Drug Info |
| COX2 --- 5LOX | 4-[2-(4-Chloro-phenyl)-vinyl]-2,6-dimethyl-phenol | Drug Info |
| COX2 --- 5LOX | BW-755C | Drug Info |
| COX2 --- 5LOX | 2-[3-Fluoro-5-(4-methoxy-tetrahydro-pyran-4-yl)-phenoxymethyl]-4-(4-fluoro-phenyl)-oxazole-5-sulfonic acid amide | Drug Info |
| COX2 --- 5LOX | 3-(4-Isopropylphenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide | Drug Info |
| COX2 --- 5LOX | 3-(4-Methoxyphenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide | Drug Info |
| COX2 --- 5LOX | 4-[2-(5-Chloro-thiophen-2-yl)-vinyl]-2,6-dimethyl-phenol | Drug Info |
| COX2 --- 5LOX | 4-[2-(2,5-Dimethyl-phenyl)-vinyl]-2,6-dimethyl-phenol | Drug Info |
| COX2 --- 5LOX | Tebufelone | Drug Info |
| COX2 --- 5LOX | 5-((Z)-3,5-di-tert-butyl-4-hydroxybenzylidene)-2-amino-4-thiazolidinone | Drug Info |
| COX2 --- 5LOX | 4-[2-(3H-1lambda*4*-Benzo[b]thiophen-3-yl)-vinyl]-2,6-dimethyl-phenol | Drug Info |
| COX2 --- 5LOX | 2-Fluoro-6-methyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | 3-(4-tert-Butylphenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide | Drug Info |
| COX2 --- 5LOX | 1-(4-Bromo-phenyl)-5-nitro-1lambda(4)-benzo[1,3,2]dithiazole 3,3-dioxide | Drug Info |
| COX2 --- 5LOX | 1-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-2-cyclopropyl-ethanone | Drug Info |
| COX2 --- 5LOX | SID11111744 | Drug Info |
| COX2 --- 5LOX | (7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-phenyl-methanone | Drug Info |
| COX2 --- 5LOX | 1-(4-chlorophenyl)-3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-5-phenyl-1H-pyrazole | Drug Info |
| COX2 --- 5LOX | 4-[2-(2,6-Difluoro-phenyl)-vinyl]-2,6-dimethyl-phenol | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-(2-naphthalen-2-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | N-{3-[5-(4-Chloro-phenyl)-1-(4-methoxy-phenyl)-1H-pyrazol-3-yl]-1-methyl-prop-2-ynyl}-N-hydroxy-acetamide | Drug Info |
| COX2 --- 5LOX | 3-(4-Trifluoromethylphenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-(2-naphthalen-1-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | 2-Methoxy-6-propyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | 6-(7-tert-Butyl-3,3-dimethyl-2,3-dihydro-benzofuran-5-yl)-imidazo[2,1-b]thiazole | Drug Info |
| COX2 --- 5LOX | N-hydroxy-N-(3-(3-phenoxyphenyl)allyl)acetamide | Drug Info |
| COX2 --- 5LOX | Enofelast | Drug Info |
| COX2 --- 5LOX | 4-[2-(4-Fluoro-phenyl)-hex-1-enyl]-2,6-dimethyl-phenol | Drug Info |
| COX2 --- 5LOX | 2,6-Diethyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | 1-(7-tert-Butyl-2,3-dihydro-benzofuran-5-yl)-hex-5-yn-1-one | Drug Info |
| COX2 --- 5LOX | 2,6-Diethyl-4-[2-(4-methoxy-phenyl)-vinyl]-phenol | Drug Info |
| COX2 --- 5LOX | 3-((3-fluoro-5-(1-methoxycyclohexyl)phenoxy)methyl)-1-(4-(methylsulfonyl)phenyl)-5-phenyl-1H-pyrazole | Drug Info |
| COX2 --- 5LOX | 3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-1-(4-methylphenyl)-5-phenyl-1H-pyrazole | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | 2-Methoxy-6-methyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-(2-thiophen-2-yl-ethyl)-phenol | Drug Info |
| COX2 --- 5LOX | 4-[2-(4-Butoxy-phenyl)-vinyl]-2,6-dimethyl-phenol | Drug Info |
| COX2 --- 5LOX | INDOMETHACIN | Drug Info |
| COX2 --- 5LOX | 3-(4-Biphenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide | Drug Info |
| COX2 --- 5LOX | 2,6-Dimethyl-4-[2-(5-methyl-thiophen-2-yl)-vinyl]-phenol | Drug Info |
| COX2 --- 5LOX | 3-[1-(3,5-Di-tert-butyl-4-hydroxy-phenyl)-meth-(Z)-ylidene]-dihydro-furan-2-one | Drug Info |
| COX2 --- 5LOX | 2,6-Di-tert-butyl-4-((Z)-2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | 2-Chloro-6-methyl-4-(2-thiophen-2-yl-vinyl)-phenol | Drug Info |
| COX2 --- 5LOX | 1-(3,4-dichlorophenyl)-3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-5-phenyl-1H-pyrazole | Drug Info |
| COX2 --- 5LOX | 3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-1-(4-fluorophenyl)-5-phenyl-1H-pyrazole | Drug Info |
| COX2 --- 5LOX | 3-[3-fluoro-5-(4-methoxytetrahydropyran-4-yl)phenoxymethyl]-1-(4-methoxyphenyl)-5-phenyl-1H-pyrazole | Drug Info |
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