Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- Cyclin E | 2-{(2-Hydroxy-ethyl)-[6-(4-methoxy-benzylamino)-9-(4-nitro-benzyl)-9H-purin-2-yl]-amino}-ethanol | Drug Info |
| CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-nitro-3-phenethyl-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
| CDK2 --- Cyclin E | N-[5-(5-tert-Butyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-2-phenyl-acetamide | Drug Info |
| CDK2 --- Cyclin E | 4-((R)-Amino-5-hydroxy-3-(S)-4-hydroxy-hex-1-ynyl)-5-fluoro-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | 1-[5-(5-tert-Butyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-3-ethyl-urea | Drug Info |
| CDK2 --- Cyclin E | N-[5-(4,5-Dimethyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
| CDK2 --- Cyclin E | (2-Chloro-9-methyl-9H-purin-6-yl)-(4-methoxy-benzyl)-amine | Drug Info |
| CDK2 --- Cyclin E | N2-(trans-4-aminocyclohexyl)-N6-((4'-chlorobiphenyl-4-yl)methyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-[6-(4-methoxy-phenyl)-2-trifluoromethyl-quinazolin-4-yl]-amine | Drug Info |
| CDK2 --- Cyclin E | (R)-2-(6-(Biphenyl-4-ylmethylamino)-9-propyl-9H-purin-2-ylamino)butan-1-ol | Drug Info |
| CDK2 --- Cyclin E | N6-((6-(1H-pyrazol-1-yl)pyridin-3-yl)methyl)-N2-(4-aminocyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | N2-(4-Aminocyclohexyl)-9-cyclopentyl-N6-(biphenyl-4-ylmethyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | 5-Hydroxy-3-(4-methoxy-phenyl)-2H-indeno[1,2-c]pyrazol-4-one | Drug Info |
| CDK2 --- Cyclin E | 2-(3-aminopyrrolidin-1-yl)-N-(biphenyl-4-ylmethyl)-9-isopropyl-9H-purin-6-amine | Drug Info |
| CDK2 --- Cyclin E | (4-Chloro-benzyl)-(2-chloro-9-trifluoromethyl-9H-purin-6-yl)-amine | Drug Info |
| CDK2 --- Cyclin E | N-((1r,4r)-4-(6-(biphenyl-4-ylmethylamino)-9-isopropyl-9H-purin-2-ylamino)cyclohexyl)-2-cyclopropylacetamide | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-[6-(2-methoxy-phenyl)-2-trifluoromethyl-quinazolin-4-yl]-amine | Drug Info |
| CDK2 --- Cyclin E | 2-[[9-Cyclopentyl-6-(4-methoxy-benzylamino)-9H-purin-2-yl]-(2-hydroxy-ethyl)-amino]-ethanol | Drug Info |
| CDK2 --- Cyclin E | 2-[{6-[(Biphenyl-4-ylmethyl)-amino]-9-isopropyl-9H-purin-2-yl}-(2-hydroxy-ethyl)-amino]-ethanol | Drug Info |
| CDK2 --- Cyclin E | N-[3-(4-Methoxy-phenyl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-2,2-dimethyl-propionamide | Drug Info |
| CDK2 --- Cyclin E | N'-[5-(2-chlorophenyl)-2,10-dihydropyrazolo[3,4-b][1,4]benzodiazepin-7-yl]-N,N-dimethylsulfamide | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((6-phenylpyridin-3-yl)methyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | N6-(biphenyl-4-ylmethyl)-N2-(trans-4-(cyclopropylmethylamino)cyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine-7-carboxamide | Drug Info |
| CDK2 --- Cyclin E | N*2*,N*6*-Bis-(4-bromo-phenyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((6-(thiophen-3-yl)pyridin-3-yl)methyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | 6-Fluoromethyl-3-methylsulfanyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 1-[(3-Isopropyl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-ylcarbamoyl)-methyl]-piperidine-4-carboxylic acid amide | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-(4-(thiophen-3-yl)benzyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | 3-[9-Isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-ylamino]-propane-1,2-diol | Drug Info |
| CDK2 --- Cyclin E | N2-(trans-4-aminocyclohexyl)-N6-((4'-fluorobiphenyl-4-yl)methyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | N6-(4-(1H-pyrazol-1-yl)benzyl)-N2-(4-aminocyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 5-fluoro-3-((3-methoxy-1H-pyrrol-2-yl)methylene)indolin-2-one | Drug Info |
| CDK2 --- Cyclin E | (3-Cyclohexyl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-urea | Drug Info |
| CDK2 --- Cyclin E | 6-(3,4-Dimethoxy-phenyl)-3-ethyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | N-(4-Oxo-3-propyl-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-acetamide | Drug Info |
| CDK2 --- Cyclin E | 5-Fluoro-4-iodo-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | 4-(4-tert-Butylamino-2-trifluoromethyl-quinazolin-6-yl)-phenol | Drug Info |
| CDK2 --- Cyclin E | (9-Isopropyl-2-pyrrolidin-1-yl-9H-purin-6-yl)-(4-methoxy-benzyl)-amine | Drug Info |
| CDK2 --- Cyclin E | 3-Ethyl-4-methoxy-6-methyl-1-(2,4,6-trichloro-phenyl)-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidine | Drug Info |
| CDK2 --- Cyclin E | 1-{6-[(Biphenyl-4-ylmethyl)-amino]-9-isopropyl-9H-purin-2-ylamino}-ethanol | Drug Info |
| CDK2 --- Cyclin E | 5-Fluoro-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | {6-[(Biphenyl-4-ylmethyl)-amino]-2-[bis-(2-hydroxy-ethyl)-amino]-purin-9-yl}-acetic acid tert-butyl ester | Drug Info |
| CDK2 --- Cyclin E | 2-[9-Isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-ylamino]-ethanol | Drug Info |
| CDK2 --- Cyclin E | 6-Benzyl-3-methylsulfanyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 2-[9-Isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-ylamino]-3-phenyl-propan-1-ol | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-(4-methylthiazol-2-yl)thiophen-2-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 3-Ethyl-6-(2-methoxy-benzyl)-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 4-((3,5-Diamino-1H-pyrazol-4-yl)diazenyl)phenol | Drug Info |
| CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-nitro-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine-3-carboxamide | Drug Info |
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