Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| CDK2 --- Cyclin E | 5-Fluoro-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-4-(3-methylamino-prop-1-ynyl)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | 5-Fluoro-4-(4-hydroxy-piperidin-4-ylethynyl)-3-[1-(3-methoxy-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one; hydrochloride | Drug Info |
| CDK2 --- Cyclin E | trans-4-(6-(biphenyl-4-ylmethylamino)-9-isopropyl-9H-purin-2-ylamino)cyclohexanol | Drug Info |
| CDK2 --- Cyclin E | (4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-p-tolyl-methanone | Drug Info |
| CDK2 --- Cyclin E | N-[5-(4,4-Dimethyl-2-oxo-pentylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
| CDK2 --- Cyclin E | N-(4-Oxo-3-pyridin-3-yl-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-acetamide | Drug Info |
| CDK2 --- Cyclin E | 2-[9-Isopropyl-6-(4-methoxy-benzylamino)-9H-purin-2-ylamino]-cyclohexanol | Drug Info |
| CDK2 --- Cyclin E | 2-{(2-Hydroxy-ethyl)-[6-(4-methoxy-benzylamino)-9-(2-methyl-butyl)-9H-purin-2-yl]-amino}-ethanol | Drug Info |
| CDK2 --- Cyclin E | (E)-2-(5-((2-acetamidothiazol-4-yl)methyl)-4-(4-chlorobenzamido)-4H-1,2,4-triazol-3-ylthio)-N'-benzylideneacetohydrazide | Drug Info |
| CDK2 --- Cyclin E | 2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(quinolin-3-ylamino)-9H-purin-2-yl]-amino}-ethanol | Drug Info |
| CDK2 --- Cyclin E | 3-((3,5-diamino-1H-pyrazol-4-yl)diazenyl)phenol | Drug Info |
| CDK2 --- Cyclin E | 5-Fluoro-4-[(R)-4-hydroxy-3-(2-hydroxy-ethylamino)-but-1-ynyl]-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-[6-(4-chloro-phenyl)-2-trifluoromethyl-quinazolin-4-yl]-amine | Drug Info |
| CDK2 --- Cyclin E | N-(3-Cyclohexyl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-acetamide | Drug Info |
| CDK2 --- Cyclin E | (4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-m-tolyl-methanone | Drug Info |
| CDK2 --- Cyclin E | 3-Ethyl-6-(4-hydroxy-3-methyl-benzyl)-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-(pyridin-3-yl)thiophen-2-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | N-[5-(5-tert-Butyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-benzenesulfonamide | Drug Info |
| CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-nitro-3-phenyl-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
| CDK2 --- Cyclin E | [4-(2-Hydroxy-ethoxy)-1H-pyrazolo[3,4-b]pyridin-5-yl]-phenyl-methanone | Drug Info |
| CDK2 --- Cyclin E | 5-Fluoro-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-4-(S)-2-pyrrolidin-2-ylethynyl-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((5-m-tolylthiophen-2-yl)methyl)-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 2-{(2-Hydroxy-ethyl)-[6-(4-methoxy-benzylamino)-9-(4-nitro-benzyl)-9H-purin-2-yl]-amino}-ethanol | Drug Info |
| CDK2 --- Cyclin E | 5-(2-chlorophenyl)-7-nitro-3-phenethyl-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine | Drug Info |
| CDK2 --- Cyclin E | N-[5-(5-tert-Butyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-2-phenyl-acetamide | Drug Info |
| CDK2 --- Cyclin E | 4-((R)-Amino-5-hydroxy-3-(S)-4-hydroxy-hex-1-ynyl)-5-fluoro-3-(3-methoxy-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one | Drug Info |
| CDK2 --- Cyclin E | 1-[5-(5-tert-Butyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-3-ethyl-urea | Drug Info |
| CDK2 --- Cyclin E | N-[5-(4,5-Dimethyl-oxazol-2-ylmethylsulfanyl)-thiazol-2-yl]-acetamide | Drug Info |
| CDK2 --- Cyclin E | (2-Chloro-9-methyl-9H-purin-6-yl)-(4-methoxy-benzyl)-amine | Drug Info |
| CDK2 --- Cyclin E | N2-(trans-4-aminocyclohexyl)-N6-((4'-chlorobiphenyl-4-yl)methyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-[6-(4-methoxy-phenyl)-2-trifluoromethyl-quinazolin-4-yl]-amine | Drug Info |
| CDK2 --- Cyclin E | (R)-2-(6-(Biphenyl-4-ylmethylamino)-9-propyl-9H-purin-2-ylamino)butan-1-ol | Drug Info |
| CDK2 --- Cyclin E | N6-((6-(1H-pyrazol-1-yl)pyridin-3-yl)methyl)-N2-(4-aminocyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | N2-(4-Aminocyclohexyl)-9-cyclopentyl-N6-(biphenyl-4-ylmethyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | 5-Hydroxy-3-(4-methoxy-phenyl)-2H-indeno[1,2-c]pyrazol-4-one | Drug Info |
| CDK2 --- Cyclin E | 2-(3-aminopyrrolidin-1-yl)-N-(biphenyl-4-ylmethyl)-9-isopropyl-9H-purin-6-amine | Drug Info |
| CDK2 --- Cyclin E | (4-Chloro-benzyl)-(2-chloro-9-trifluoromethyl-9H-purin-6-yl)-amine | Drug Info |
| CDK2 --- Cyclin E | N-((1r,4r)-4-(6-(biphenyl-4-ylmethylamino)-9-isopropyl-9H-purin-2-ylamino)cyclohexyl)-2-cyclopropylacetamide | Drug Info |
| CDK2 --- Cyclin E | tert-Butyl-[6-(2-methoxy-phenyl)-2-trifluoromethyl-quinazolin-4-yl]-amine | Drug Info |
| CDK2 --- Cyclin E | 2-[[9-Cyclopentyl-6-(4-methoxy-benzylamino)-9H-purin-2-yl]-(2-hydroxy-ethyl)-amino]-ethanol | Drug Info |
| CDK2 --- Cyclin E | 2-[{6-[(Biphenyl-4-ylmethyl)-amino]-9-isopropyl-9H-purin-2-yl}-(2-hydroxy-ethyl)-amino]-ethanol | Drug Info |
| CDK2 --- Cyclin E | N-[3-(4-Methoxy-phenyl)-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl]-2,2-dimethyl-propionamide | Drug Info |
| CDK2 --- Cyclin E | N'-[5-(2-chlorophenyl)-2,10-dihydropyrazolo[3,4-b][1,4]benzodiazepin-7-yl]-N,N-dimethylsulfamide | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((6-phenylpyridin-3-yl)methyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | N6-(biphenyl-4-ylmethyl)-N2-(trans-4-(cyclopropylmethylamino)cyclohexyl)-9-isopropyl-9H-purine-2,6-diamine hydrochloride | Drug Info |
| CDK2 --- Cyclin E | 5-(2-fluorophenyl)-2,10-dihydrobenzo[e]pyrazolo[4,3-b][1,4]diazepine-7-carboxamide | Drug Info |
| CDK2 --- Cyclin E | N*2*,N*6*-Bis-(4-bromo-phenyl)-9-isopropyl-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | N2-(4-aminocyclohexyl)-9-isopropyl-N6-((6-(thiophen-3-yl)pyridin-3-yl)methyl)-9H-purine-2,6-diamine | Drug Info |
| CDK2 --- Cyclin E | 6-Fluoromethyl-3-methylsulfanyl-1-(2,4,6-trichloro-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one | Drug Info |
| CDK2 --- Cyclin E | 1-[(3-Isopropyl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-ylcarbamoyl)-methyl]-piperidine-4-carboxylic acid amide | Drug Info |
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