Multi-target agents
| Target Pair | Drug Name | |
|---|---|---|
| ADRA1A --- HRH1 | 4-[(4-Chlorophenyl)methyl]-2-(2-{[4-(4-{[3-(hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]amino}ethyl)-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | 4-[(4-Hydroxyphenyl)methyl]-2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | 2,8-Dimethyl-5-(2-p-tolylethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | Drug Info |
| ADRA1A --- HRH1 | CHEMBL1178351 | Drug Info |
| ADRA1A --- HRH1 | Zonalon | Drug Info |
| ADRA1A --- HRH1 | DROPERIDOL | Drug Info |
| ADRA1A --- HRH1 | CHEMBL2068762 | Drug Info |
| ADRA1A --- HRH1 | 2-({(2R)-1-[4-(4-{[3-(Hexahydro-1H-azepin-1-yl)propyl]oxy}phenyl)butyl]-2-pyrrolidinyl}methyl)-4-[(4-hydroxyphenyl)methyl]-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | N-((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)-3-methylbenzamide | Drug Info |
| ADRA1A --- HRH1 | 7-[3-(4-Benzhydryl-piperidin-1-yl)-propyl]-1,3-dimethyl-3,7-dihydro-purine-2,6-dione; compound with (E)-but-2-enedioic acid | Drug Info |
| ADRA1A --- HRH1 | 2,8-dimethyl-5-phenethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | Drug Info |
| ADRA1A --- HRH1 | methyl 1-(3-(5-(ethylcarbamoyl)-2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3-carboxamido)propyl)-4-phenylpiperidine-4-carboxylate | Drug Info |
| ADRA1A --- HRH1 | 2-(4-Dimethylamino-phenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxylic acid {2-hydroxy-3-[4-(2-isopropoxy-phenyl)-piperazin-1-yl]-propyl}-amide | Drug Info |
| ADRA1A --- HRH1 | 4-{[4-(Ethyloxy)phenyl]methyl}-2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | 4-[(4-Chlorophenyl)methyl]-2-{2-[[4-(4-{[3-(hexahydro-1Hazepin-1-yl)propyl]oxy}phenyl)butyl](methyl)amino]ethyl}-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | (R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2,4-difluoro-phenyl)-piperidin-1-yl]-propyl}-amide | Drug Info |
| ADRA1A --- HRH1 | 4-[(4-Chlorophenyl)methyl]-2-(1-methylhexahydro-1H-azepin-3-yl)-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | 2-{[(2R)-1-Butyl-2-pyrrolidinyl]methyl}-4-[(4-chlorophenyl)methyl]-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | Azelastine | Drug Info |
| ADRA1A --- HRH1 | 4-(3-(4-chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)-1-(4-fluorophenyl)butan-1-one | Drug Info |
| ADRA1A --- HRH1 | 4-{[4-(Methyloxy)phenyl]methyl}-2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | Thiazinamium | Drug Info |
| ADRA1A --- HRH1 | (11-Chloro-2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine | Drug Info |
| ADRA1A --- HRH1 | 2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-4-(2-phenylethyl)-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | SID170465966 | Drug Info |
| ADRA1A --- HRH1 | (R)-4-(3,4-Difluoro-phenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid {3-[4-cyano-4-(2-cyano-phenyl)-piperidin-1-yl]-propyl}-amide | Drug Info |
| ADRA1A --- HRH1 | Amitriptyline | Drug Info |
| ADRA1A --- HRH1 | CHEMBL1620822 | Drug Info |
| ADRA1A --- HRH1 | Pipamazine | Drug Info |
| ADRA1A --- HRH1 | OLANZAPINE_N-OXIDE METABOLITE | Drug Info |
| ADRA1A --- HRH1 | Trazodone | Drug Info |
| ADRA1A --- HRH1 | PROCHLORPERAZINE | Drug Info |
| ADRA1A --- HRH1 | (5,11-Difluoro-2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-ylmethyl)-dimethyl-amine | Drug Info |
| ADRA1A --- HRH1 | Amoxapine | Drug Info |
| ADRA1A --- HRH1 | 4-[(3-Chlorophenyl)methyl]-2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | 5-Methoxy-3-{4-[4-(4-methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole | Drug Info |
| ADRA1A --- HRH1 | 2-{2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-piperazin-1-yl)-ethoxy]-ethoxy}-ethanol | Drug Info |
| ADRA1A --- HRH1 | 4-(4-chlorobenzyl)-2-(2-(1-methylpyrrolidin-2-yl)ethyl)phthalazin-1(2H)-one | Drug Info |
| ADRA1A --- HRH1 | Methyl-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-ylmethyl)-amine | Drug Info |
| ADRA1A --- HRH1 | (1S,5S,6S)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)-3-azabicyclo[3.1.0]hexane | Drug Info |
| ADRA1A --- HRH1 | 1-(Diphenylmethyl)-4-(3-phenylpropyl)piperazine | Drug Info |
| ADRA1A --- HRH1 | cis-(-)-7,8-dimethoxy-3-[4-(2-methyl-3-(4-fluoro)phenyl-2(E)-propen-1-yl)piperazin-1-ylmethyl]-3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazole | Drug Info |
| ADRA1A --- HRH1 | SID144207521 | Drug Info |
| ADRA1A --- HRH1 | N-(((cis)-4-(4-(dimethylamino)-5-methylpyrimidin-2-ylamino)cyclohexyl)methyl)-3,4-difluorobenzamide | Drug Info |
| ADRA1A --- HRH1 | (8-methyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole | Drug Info |
| ADRA1A --- HRH1 | 3-{4-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carboxylic acid amide | Drug Info |
| ADRA1A --- HRH1 | SID170465934 | Drug Info |
| ADRA1A --- HRH1 | 4-[(3,4-Difluorophenyl)methyl]-2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-1(2H)-phthalazinone | Drug Info |
| ADRA1A --- HRH1 | Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetrahydro-1-oxa-12b-aza-dibenzo[e,h]azulen-2-yl)methyl]-amine | Drug Info |
| ADRA1A --- HRH1 | Esmirtazapine | Drug Info |
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