Drug General Information
Drug ID
DXYO7V
Drug Name
2-{[(2R)-1-methyl-2-pyrrolidinyl]methyl}-4-(2-phenylethyl)-1(2H)-phthalazinone
Synonyms
CHEMBL1767152
Indication Discovery agent Investigative [1587926]
Formula
C22H25N3O
Canonical SMILES
CN1CCC[C@@H]1CN2N=C(CCc3ccccc3)c4ccccc4C2=O
InChI
InChI=1S/C22H25N3O/c1-24-15-7-10-18(24)16-25-22(26)20-12-6-5-11-19(20)21(23-25)14-13-17-8-3-2-4-9-17/h2-6,8-9,11-12,18H,7,10,13-16H2,1H3/t18-/m1/s1
InChIKey
VHHWNRROUCRXSK-GOSISDBHSA-N
Target and Pathway
Target(s) Alpha-1 adrenergic receptor Target Info [1587926]
Histamine H1 receptor Target Info [1587926]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
PANTHER Pathway Histamine H1 receptor mediated signaling pathway
Reactome Histamine receptors
G alpha (q) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
IL-4 Signaling Pathway
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017
Ref 1587926URL: https://www.ebi.ac.uk/chembl/ The ChEMBL database in 2017

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