| Drug General Information |
| Drug ID |
D0A4FU
|
| Former ID |
DNC010896
|
| Drug Name |
1-(2-allylphenoxy)-3-morpholinopropan-2-ol
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C16H23NO3
|
| Canonical SMILES |
C=CCC1=CC=CC=C1OCC(CN2CCOCC2)O
|
| InChI |
1S/C16H23NO3/c1-2-5-14-6-3-4-7-16(14)20-13-15(18)12-17-8-10-19-11-9-17/h2-4,6-7,15,18H,1,5,8-13H2
|
| InChIKey |
BKDPODVOOWQEGE-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Beta-2 adrenergic receptor |
Target Info |
Inhibitor |
[1]
|
|---|
| Beta-1 adrenergic receptor |
Target Info |
Inhibitor |
[1]
|
| Beta-3 adrenergic receptor |
Target Info |
Inhibitor |
[1]
|
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KEGG Pathway
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Calcium signaling pathway
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cGMP-PKG signaling pathway
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cAMP signaling pathway
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Neuroactive ligand-receptor interaction
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Endocytosis
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Adrenergic signaling in cardiomyocytes
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Salivary secretionhsa04020:Calcium signaling pathway
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Gap junction
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Salivary secretion
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Dilated cardiomyopathyhsa04020:Calcium signaling pathway
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NetPath Pathway
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TCR Signaling Pathway
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PANTHER Pathway
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Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
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Beta2 adrenergic receptor signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
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Beta1 adrenergic receptor signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
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Beta3 adrenergic receptor signaling pathway
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Pathway Interaction Database
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Arf6 trafficking events
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Arf6 signaling events
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PathWhiz Pathway
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Muscle/Heart Contraction
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Reactome
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Adrenoceptors
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G alpha (s) signalling eventsR-HSA-390696:Adrenoceptors
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G alpha (s) signalling events
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WikiPathways
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Monoamine GPCRs
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Calcium Regulation in the Cardiac Cell
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GPCRs, Class A Rhodopsin-like
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Vitamin D Receptor Pathway
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GPCR ligand binding
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GPCR downstream signaling
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GPCRs, OtherWP58:Monoamine GPCRs
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Endothelin Pathways
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GPCR downstream signalingWP58:Monoamine GPCRs
|
| References |
| REF 1 | Bioorg Med Chem Lett. 2010 Jun 1;20(11):3399-404. Epub 2010 Apr 9.A vHTS approach for the identification of beta-adrenoceptor ligands. |
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