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Target General Information |
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Target ID |
T71023 |
Target Info
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Target Name |
Synaptosomal-associated protein 25 (SNAP25) |
Synonyms |
Synaptosomal-associated 25 kDa protein; Super protein; SUP; SNAP-25; SNAP |
Target Type |
Successful Target |
Gene Name |
SNAP25 |
Biochemical Class |
Synaptosomal vesicle fusion pore |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-27a-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
agggcuuagcugcuugugagca
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
miR-27a directly suppressed SNAP25 expressions through post-transcriptional gene silencing. |
[1] |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay; Western Blot |
[1] |
Representative Target(s) Regulated by This miRNA |
Epidermal growth factor receptor (EGFR)
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Target Info
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Gremlin-1 (Gremlin-1)
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Target Info
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miRNA Mature ID |
hsa-miR-641 |
miRNA Info
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miRNA Mature AC |
|
Sequence |
aaagacauaggauagagucaccuc
|
miRNA Species |
Homo sapiens |
Evidence Score (E-score) |
1 |
+ |
1 |
Luciferase Reporter Assay |
[2] |
Representative Target(s) Regulated by This miRNA |
Synaptosomal-associated protein 25 (SNAP25)
|
Target Info
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References |
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REF 1 |
MicroRNA miR-27 Inhibits Adenovirus Infection by Suppressing the Expression of SNAP25 and TXN2. J Virol. 2017 May 26;91(12). pii: e00159-17.
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REF 2 |
Association of impulsivity and polymorphic microRNA-641 target sites in the SNAP-25 gene. PLoS One. 2013 Dec 31;8(12):e84207.
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