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Target General Information |
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Target ID |
T38529 |
Target Info
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Target Name |
Prostaglandin E2 receptor EP2 (PTGER2) |
Synonyms |
Prostanoid EP2 receptor; Prostaglandin E2 receptor EP2 subtype; PGE2 receptor EP2 subtype; PGE receptor, EP2 subtype; PGE receptor EP2 subtype; EP2 receptor |
Target Type |
Successful Target |
Gene Name |
PTGER2 |
Biochemical Class |
GPCR rhodopsin |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-149-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
ucuggcuccgugucuucacuccc
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miRNA Species |
Homo sapiens |
Evidence Score (E-score) |
1 |
+ |
1 |
ELISA; Luciferase Reporter Assay; Western Blot |
[1] |
Representative Target(s) Regulated by This miRNA |
Apoptosis antigen ligand (CD178)
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Target Info
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Bcl-2-binding component 3 (BBC3)
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Target Info
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References |
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REF 1 |
Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment. Cell Res. 2015 May;25(5):588-603.
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