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Target General Information |
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Target ID |
T19334 |
Target Info
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Target Name |
Interleukin 21 receptor (IL21R) |
Synonyms |
UNQ3121/PRO10273; Novel interleukin receptor; NILR; Interleukin-21 receptor; IL21 receptor; IL-21R; IL-21 receptor; CD360 |
Target Type |
Clinical trial Target |
Gene Name |
IL21R |
Biochemical Class |
Cytokine receptor |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-30a-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
uguaaacauccucgacuggaag
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miRNA Species |
Homo sapiens |
Evidence Score (E-score) |
2 |
+ |
1 |
HITS-CLIP |
[1] |
2 |
Luciferase Reporter Assay |
[2] |
Representative Target(s) Regulated by This miRNA |
Beclin-1 (BECN1)
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Target Info
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Brain-derived neurotrophic factor (BDNF)
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Target Info
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References |
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REF 1 |
EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency. EMBO J. 2012 May 2;31(9):2207-21.
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REF 2 |
MiR-30a inhibits Th17 differentiation and demyelination of EAE mice by targeting the IL-21R. Brain Behav Immun. 2016 Oct;57:193-199.
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