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Target General Information |
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Target ID |
T13075 |
Target Info
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Target Name |
Casein kinase I alpha (CSNK1A1) |
Synonyms |
Casein kinase I isoform alpha; CKI-alpha; CK1 |
Target Type |
Clinical trial Target |
Gene Name |
CSNK1A1 |
Biochemical Class |
Kinase |
UniProt ID |
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The microRNAs (miRNAs) Regulating This Target |
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miRNA Mature ID |
hsa-miR-155-5p |
miRNA Info
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miRNA Mature AC |
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Sequence |
uuaaugcuaaucgugauagggguu
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miRNA Species |
Homo sapiens |
Regulation Mechanism |
Casein kinase 1 a (CK1a ) is a novel miR-155 target. |
[2] |
Evidence Score (E-score) |
3 |
+ |
1 |
Luciferase Reporter Assay |
[1] |
2 |
Proteomics |
[2] |
3 |
Reporter Assay |
[3] |
Representative Target(s) Regulated by This miRNA |
Acetyl-CoA transporter (SLC33A1)
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Target Info
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Angiotensin II receptor type-1 (AGTR1)
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Target Info
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References |
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REF 1 |
MiR-155 is a liposarcoma oncogene that targets casein kinase-1 and enhances -catenin signaling. Cancer Res. 2012 Apr 1;72(7):1751-62.
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REF 2 |
Widespread changes in protein synthesis induced by microRNAs.Nature. 2008 Sep 4;455(7209):58-63.
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REF 3 |
Transcriptome and targetome analysis in MIR155 expressing cells using RNA-seq. RNA. 2010 Aug;16(8):1610-22.
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