Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T59445 | Target Info | |||
| Target Name | Sorbitoldehydrogenase (SORD) | ||||
| Synonyms |
SORD; SDH; L-iditol2-dehydrogenase
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| Target Type | Literature-reported Target | ||||
| Gene Name | SORD | ||||
| Biochemical Class | Short-chain dehydrogenases reductase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 10 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
Epalrestat
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Approved | Compound Info | ||
| Synonyms |
epalrestat; 82159-09-9; Kinedak; Epalrestatum; Ono 2235; Ono-2235; Epalrestat [INN]; Epalrestatum [Latin]; ONO-2; 2-((z)-5-((e)-2-methyl-3-phenylallylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid; ONO 2; UNII-424DV0807X; C15H13NO3S2; CHEMBL56337; 5-((1Z,2E)-2-Methyl-3-phenylpropenylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid; CHEBI:31539; 5-((Z,E)-beta-Methylcinnamylidene)-4-oxo-2-thioxo-3-thiazolidineacetic acid; 424DV0807X; Epalrestatum; Aldorin (TN); Kinedak (TN); Epalrestat (JAN/INN); {5-[(E)-2-Methyl-3-phenyl-prop-2-en-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-acetic acid; {(5Z)-5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid; 2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid; 3-carboxymethyl-5-(methyl-3-phenylpropenylidene)rhodanine; Ono 2
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| Activity |
IC50 = 67700 nM
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[1] | |||
| Compound Name |
Flavonoid derivative 4
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Patented | Compound Info | ||
| Synonyms |
PMID26394986-Compound-48
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| Activity |
IC50 = 177000 nM
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[2] | |||
| Compound Name |
7-Hydroxy-4-phenylcoumarin
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Investigative | Compound Info | ||
| Synonyms |
7-Hydroxy-4-phenylcoumarin; 2555-30-8; 7-hydroxy-4-phenyl-2H-chromen-2-one; 7-hydroxy-4-phenylchromen-2-one; NSC78474; 4-Phenyl-7-hydroxycoumarin; UNII-L0487H6Q0H; CHEMBL325841; L0487H6Q0H; 7-Hydroxy-4-phenyl-chromen-2-one; 7-oxidanyl-4-phenyl-chromen-2-one; NSC-78474; 2H-1-Benzopyran-2-one,7-hydroxy-4-phenyl-; 2H-1-Benzopyran-2-one, 7-hydroxy-4-phenyl-; 4-Phenylumbelliferone; PubChem8691; Coumarin derivative, 3c; AC1NSAV1; 7-Hydroxy4-phenylcoumarin; Oprea1_774373; 7-hydroxy-4-phenyl coumarin; MLS001143868; SCHEMBL2987658
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| Activity |
IC50 = 70700 nM
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[1] | |||
| Compound Name |
esculetin
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Investigative | Compound Info | ||
| Synonyms |
aesculetin; 6,7-dihydroxycoumarin; cichorigenin
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| Activity |
IC50 = 82900 nM
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[1] | |||
| Compound Name |
7-hydroxycoumarin
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Investigative | Compound Info | ||
| Synonyms |
Umbelliferone; 93-35-6; 7-Hydroxy-2H-chromen-2-one; Skimmetin; Hydrangin; 7-hydroxycoumarine; 7-Oxycoumarin; Umbelliferon; Skimmetine; Hydrangine; 2H-1-Benzopyran-2-one, 7-hydroxy-; 7-Hydroxy-2H-1-benzopyran-2-one; Coumarin, 7-hydroxy-; beta-Umbelliferone; 7-hydroxychromen-2-one; 7 HC; UNII-60Z60NTL4G; 7-hydroxy-coumarin; NSC 19790; CCRIS 3591; NSC19790; EINECS 202-240-3; 7H-1-Benzopyran-7-one, 2-hydroxy-; BRN 0127683; CHEMBL51628; AI3-38054; 7-hydroxy-1-benzopyran-2-one; 7-HC; 60Z60NTL4G; CHEBI:27510; UMBELLIFERONE
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| Activity |
IC50 = 120000 nM
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[1] | |||
| Compound Name |
HERNIARIN
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Investigative | Compound Info | ||
| Synonyms |
7-Methoxycoumarin; Herniarin; 531-59-9; 7-Methoxy-2H-chromen-2-one; Ayapanin; Herniarine; Methylumbelliferone; 7-Methoxy-2H-1-benzopyran-2-one; 7-methoxychromen-2-one; 2H-1-BENZOPYRAN-2-ONE, 7-METHOXY-; Coumarin, 7-methoxy-; METHOXYCOURMARIN, 7-; Herniarin (6CI); Methyl umbelliferyl ether; UNII-DGK72G008A; 7-methoxy-coumarin; 7-Methoxy Coumarin; NSC 404559; 7-(methyloxy)-2H-chromen-2-one; EINECS 208-513-3; 7-methoxy-chromen-2-one; BRN 0141728; CHEMBL49732; CHEBI:5679; DGK72G008A; Coumarin, 7-methoxy- (8CI)
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| Activity |
IC50 = 124000 nM
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[1] | |||
| Compound Name |
SCOPOLETIN
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Investigative | Compound Info | ||
| Synonyms |
scopoletin; 92-61-5; Gelseminic acid; 6-Methylesculetin; 7-Hydroxy-6-methoxy-2H-chromen-2-one; Chrysatropic acid; Scopoletine; 7-Hydroxy-6-methoxycoumarin; Scopoletol; Murrayetin; 6-O-Methylesculetin; Escopoletin; 6-Methoxy-7-hydroxycoumarin; 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one; 6-Methoxyumbelliferone; 2H-1-Benzopyran-2-one, 7-hydroxy-6-methoxy-; Esculetin 6-methyl ether; beta-Methylesculetin; Esculetin-6-methyl ether; .beta.-Methylesculetin; Buxuletin; UNII-KLF1HS0SXJ; COUMARIN, 7-HYDROXY-6-METHOXY-
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| Activity |
IC50 = 137000 nM
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[1] | |||
| Compound Name |
3-Hydroxycoumarin
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Investigative | Compound Info | ||
| Synonyms |
3-hydroxy-2H-chromen-2-one; 3-Hydroxy-2-benzopyrone; 3-hydroxychromen-2-one; 3 Hydroxycoumarin; hydroxycoumarin; 3-Hydroxy-2H-1-benzopyran-2-one; UNII-RQX0CMD9PN; 3-Hydroxy-chromen-2-one; RQX0CMD9PN; CHEMBL150372; 2H-1-Benzopyran-2-one, hydroxy-; EINECS 213-355-3; NSC 74691; 2H-1-Benzopyran-2-one, 3-hydroxy-; BRN 0128032; COUMARIN, 3-HYDROXY-; 3-hydroxy-coumarin; 3-hydroxychromenone; NSC74691; Spectrum_000476; SpecPlus_000860; Spectrum2_000805; Spectrum3_001267; Spectrum4_001576; Spectrum5_000232; 2H-1-Benzopyran-2-one, 3-hydroxy- (9CI); hydroxy-2H-chromen-2-one; SCHEMBL76090; BSPBio_002834; KBioGR_002132; KBioSS_000956; SPECTRUM211538; 5-18-01-00376 (Beilstein Handbook Reference); DivK1c_006956; SPBio_000669; CTK1D2829; KBio1_001900; KBio2_000956; KBio2_003524; KBio2_006092; KBio3_002334; DTXSID50239863; o-Hydroxyphenylpyruvic acid lactone; ZINC336205; 2H-1-Benzopyran-2-one,3-hydroxy-; 3767AF; BDBM50206007; CCG-39664; MFCD00017490; NSC-74691; SBB056328; AKOS015916452; MCULE-4074896000; SDCCGMLS-0066523.P001; NCGC00095536-01; NCGC00095536-02; NCGC00178445-01; DB-057448; HY-127170; CS-0094421; FT-0633159; ST50331499; AN-829/40355682; BRD-K92019075-001-02-0; Q27194434
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| Activity |
IC50 = 106000 nM
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[1] | |||
| Compound Name |
Hymecromone
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Investigative | Compound Info | ||
| Synonyms |
4-methylumbelliferone; 7-HYDROXY-4-METHYLCOUMARIN; 7-Hydroxy-4-methyl-2H-chromen-2-one; Imecromone; beta-Methylumbelliferone; Cholestil; Mendiaxon; 4-Methyl-7-hydroxycoumarin; Bilcolic; Bilicante; Cantabilin; Cantabiline; Coumarin 4; Cholonerton; Hymecromon; Crodimon; Eurogale; Medilla; Cumarote-C; Omega 127; Pilot 447; 2H-1-Benzopyran-2-one, 7-hydroxy-4-methyl-; 4-Methylumbelliferon; Himecromona; Hymecromonum; 7-Hydroxy-4-methyl-2H-1-benzopyran-2-one; NSC 9408; NSC 19026; 7-Hydroxy-4-methyl-2-oxo-2H-1-benzopyran; LM 94; 4-Methylumbelliferone (4-MU); Coumarin, 7-hydroxy-4-methyl-; 7-hydroxy-4-methylchromen-2-one; 7-hydroxy-4-methyl-chromen-2-one; 7-hydroxy-4-methyl-coumarin; 2H-1-Benzopyran, 7-hydroxy-4-methyl-2-oxo-; 2H-1-Benzopyren-2-one, 7-hydroxy-4-methyl-; 7-Hydroxy-4-methyl-2-oxo-3-chromene; UNII-3T5NG4Q468; NSC9408; LM-94; NSC19026; MFCD00006866; .beta.-Methylumbelliferone; 7-hydroxy-4-methyl coumarin; 4-Methyl-7-hydroxy-coumarin; CHEMBL12208; Resocyanine; 2H-1-Benzopyran-2-one,7-hydroxy-4-methyl-; 3T5NG4Q468; NSC-9408; NSC-19026; NCGC00016345-01; DSSTox_CID_5670; DSSTox_RID_77877; DSSTox_GSID_25670; Imecromone [DCIT]; METHYLUMBELLIFERONE, BETA; WLN: T66 BOVJ E1 IQ; Cholspasmin; Hymechrome; 7-Hydroxy-4-methylcoumarin, 97%; Hymecromonum [INN-Latin]; Himecromona [INN-Spanish]; SMR000471886; 4-Methylumbelliferon [Czech]; 4 Methylumbelliferone; CCRIS 5926; EINECS 201-986-7; BRN 0142217; Himecol; AI3-08085; Biliton H; Hymecromohe,(S); Cantabiline (TN); Hymecromone [USAN:INN:BAN:JAN]; A-Methylumbelliferone; 4-methyl umbelliferone; 4-Methyl-umbelliferone; Coumarin derivative, 3b; Maybridge1_002078; Prestwick0_000901; Prestwick1_000901; Prestwick2_000901; Prestwick3_000901; Umbelliferone, 4-methyl-; 7-Hydroxy-4-methlcoumarin; Methylumbelliferone, .beta.; 4-methyl-7-hydroxy-cumarin; 7-hydroxy-4-methyl-coumari; SCHEMBL24150; BSPBio_000742; 5-18-01-00439 (Beilstein Handbook Reference); 7-hydroxy-4-methyl coumarine; KSC498C0B; MLS001074671; MLS004491718; 4-Methyl-7-hydroxyl Coumarin; SPBio_002941; 4-Methylumbelliferone - 4-MU; AMBZ0098; BPBio1_000818; MEGxp0_001898; 7-hydroxy-4-methyl-2-coumarin; 4-Methylumbelliferone, >=98%; DTXSID8025670; ACon1_002401; cid_5280567; CTK2G4039; CTK3J8100; HMS547G10; Hymecromone (JP17/USAN/INN); ZINC58121; 7-Hydroxy-4-methyl-2-chromenone; HMS1570F04; HMS2097F04; HMS2267L19; HMS3264E04; HMS3655L16; HMS3714F04; Pharmakon1600-01506174; 4-methyl-7-oxidanyl-chromen-2-one; BCP06770; HY-N0187; KS-00000JR8; Tox21_110385; Tox21_300915; ANW-43852; BBL000531; BDBM50022178; CCG-47894; NSC760397; s2256; SBB009085; STK364326; 7-Hydroxy-4-methyl-2H-2-chromenone; AKOS000119370; Tox21_110385_1; AM85958; CS-7560; DB07118; MCULE-3913656430; NSC-760397; 7-hydroxy-4-methyl-1-benzopyran-2-one; NCGC00016345-02; NCGC00016345-03; NCGC00016345-04; NCGC00016345-05; NCGC00016345-08; NCGC00016345-09; NCGC00169880-01; NCGC00169880-02; NCGC00257522-01; 7-Hydroxy-4-methyl-2H-chromen-2-one #; AC-22306; AK-72865; AS-13247; BR-72865; NCI60_042099; SC-25664; DB-029370; 2-Hydroxy-4-methyl-7H-1-benzopyran-7-one; AB00443536; B6001; FT-0602257; FT-0658701; FT-0660634; M0453; ST50102505; SW197287-3; 7H-1-Benzopyran-7-one, 2-hydroxy-4-methyl-; A-8711; C03081; D00170; M-5410; AB00443536_08; A843515; Q904431; SR-01000637483; SR-01000637483-1; SR-01000637483-3; BRD-K46424862-001-02-6; BRD-K46424862-001-04-2; F0849-0318; F1918-0038
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| Activity |
IC50 = 153000 nM
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[1] | |||
| Compound Name |
7-Hydroxycoumarin-4-acetic acid
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Investigative | Compound Info | ||
| Synonyms |
2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetic acid; 2-(7-hydroxy-2-oxochromen-4-yl)acetic acid; 7-Hydroxy-4-coumarinylacetic acid; Umbelliferone-4-acetic acid; 7-Hydroxy-2-oxo-2H-1-benzopyran-4-acetic acid; CHEMBL12253; 2H-1-Benzopyran-4-acetic acid, 7-hydroxy-2-oxo-; (7-hydroxycoumarin-4-yl)acetic acid; MFCD00037563; NSC642907; 7-Hydroxycoumarinyl-4-acetic acid, 97%; 2H-1-Benzopyran-4-aceticacid, 7-hydroxy-2-oxo-; 7-Hca cpd; NSC65625; zlchem 418; ACMC-1BA4W; NCIOpen2_003061; Oprea1_344287; Oprea1_675178; SCHEMBL263980; 7-Hydroxycoumarin-4acetic acid; IFLab1_004900; 7-hydroxy-4-coumarinacetic acid; CTK2F5210; KS-00000GHX; DTXSID50943938; ZLC0273; 7-hydroxy-coumarin-4-acetic acid; 7-Hydroxycoumarin-4-ylacetic acid; HMS1425O16; ZINC153920; 7-Hydroxyl-coumarin-4-acetic acid; ALBB-015615; 8284AE; BDBM50022182; NSC-65625; SBB065747; STK408788; (7-hydroxycoumarin-4-yl) acetic acid; AKOS005175214; MCULE-6299044943; NSC-642907; IDI1_010655; AK307577; DS-11403; SY050406; AB0070761; DB-055289; FT-0636308; ST50319902; (7-hydroxy-2-oxo-2H-chromen-4-yl)acetic acid; 2-(7-hydroxy-2-oxo-chromen-4-yl)acetic acid; A21440; C-5409; H-4555; 2-Oxo-7-hydroxy-2H-1-benzopyran-4-acetic acid; (7-Hydroxy-2-oxo-2H-chromen-4-yl)-acetic acid; J-100175; (7-Hydroxy-2-oxo-2H-1-benzopyran-4-yl)acetic acid; 7-HYDROXY-2-OXO-2H-1-BENZOPYRAN-4-ACETICACID; F1083-0012
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| Activity |
IC50 = 163000 nM
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[1] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 7 non binders) | Download | Top | |||
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| Compound Name |
ISOSCOPOLETIN
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Investigative | Compound Info | ||
| Synonyms |
Isoscopoletin; 776-86-3; 6-Hydroxy-7-methoxycoumarin; 6-hydroxy-7-methoxy-2H-chromen-2-one; 7-Methoxyesculetin; Isoscopoletine; 6-hydroxy-7-methoxychromen-2-one; 2H-1-Benzopyran-2-one, 6-hydroxy-7-methoxy-; 6-hydroxy-7-methoxy-chromen-2-one; CHEMBL390320; CHEBI:81484; iso-scopoletin; 6-Hydroxy-7-methoxy-2-benzopyrone; EINECS 212-282-4; AC1L2CWN; Esculetin 7-methyl ether; Esculetin, 7-methyl ether; AC1Q4EZ0; 6-Hydroxy-7-methylcoumarin; SCHEMBL2790887; AC1Q69W0; CTK7A0381; DTXSID40228266; MolPort-003-927-047
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| Activity |
IC50 > 250000 nM
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[1] | |||
| Compound Name |
COUMARIN
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Investigative | Compound Info | ||
| Synonyms |
coumarin; 2H-Chromen-2-one; 91-64-5; 2H-1-Benzopyran-2-one; cumarin; 1,2-Benzopyrone; Rattex; Tonka bean camphor; Coumarinic anhydride; chromen-2-one; Coumarine; Benzo-alpha-pyrone; cis-o-Coumarinic acid lactone; o-Hydroxycinnamic acid lactone; o-Hydroxycinnamic lactone; 2-Oxo-1,2-benzopyran; Coumarinic lactone; Kumarin; Benzo-a-pyrone; Kumarin [Czech]; 5,6-Benzo-2-pyrone; 2H-1-Benzopyran, 2-oxo-; 5,6-Benzo-alpha-pyrone; 2H-Benzo(b)pyran-2-one; 2H-Benzo[b]pyran-2-one; Caswell No. 259C; o-Coumaric acid lactone
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| Activity |
IC50 > 400000 nM
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[1] | |||
| Compound Name |
4-Methylesculetin
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Investigative | Compound Info | ||
| Synonyms |
6,7-DIHYDROXY-4-METHYLCOUMARIN; 6,7-Dihydroxy-4-methyl-2H-chromen-2-one; Methylesculetin; 4-Methylaesculetin; 4-Methylesculetol; 4-Methyl-6,7-dihydroxycoumarin; 6,7-dihydroxy-4-methylchromen-2-one; 6,7-Dihydroxy-4-methyl-2H-benzopyran-2-one; 2H-1-Benzopyran-2-one, 6,7-dihydroxy-4-methyl-; Coumarin, 6,7-dihydroxy-4-methyl-; NSC 11828; NSC 688807; UNII-132H8N0A91; 6,7-Dihydroxy-4-methyl-2H-1-benzopyran-2-one; 6,7-Dihydroxy-4-methyl-chromen-2-one; CHEMBL313244; NSC11828; MFCD00006859; NSC688807; 132H8N0A91; NSC-688807; SR-01000389898; EINECS 208-470-0; BRN 0162550; AI3-18220; Spectrum_001029; SpecPlus_000495; Spectrum2_000617; Spectrum3_000592; Spectrum4_001864; Spectrum5_000428; Oprea1_739367; BSPBio_002064; KBioGR_002330; KBioSS_001509; 5-18-03-00231 (Beilstein Handbook Reference); DivK1c_006591; SCHEMBL409482; SPECTRUM1500729; SPBio_000554; DTXSID6060187; 4-methy1-6,7-dihydroxycoumarin; KBio1_001535; KBio2_001509; KBio2_004077; KBio2_006645; KBio3_001564; ZINC58125; ALBB-015650; HY-N4288; KS-000013XH; 7498AB; ANW-43466; BBL027618; BDBM50078820; CCG-38534; NSC-11828; s4966; SBB057778; STL372185; AKOS003241110; GS-5460; MCULE-2984770490; SDCCGMLS-0066617.P001; NCGC00095628-01; NCGC00095628-02; NCGC00178836-01; 4-methyl-6,7-bis(oxidanyl)chromen-2-one; DB-052228; 6,7-dihydroxy-4-methyl-1-benzopyran-2-one; CS-0032643; EU-0066858; FT-0619082; M0766; R1156; ST45024832; A829333; SR-01000389898-1; SR-01000389898-2; W-200029; Q27251461; F1011-0383
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| Activity |
IC50 = 212000 nM
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[1] | |||
| Compound Name |
Nordalbergin
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Investigative | Compound Info | ||
| Synonyms |
6,7-Dihydroxy-4-phenyl-2H-chromen-2-one; 6,7-Dihydroxy-4-phenylcoumarin; 6,7-dihydroxy-4-phenylchromen-2-one; CHEMBL1255818; Oprea1_012343; CBDivE_012029; SCHEMBL1706321; CTK8B6766; DTXSID40415775; ZINC186764; BCP21930; HY-N4287; 6606AB; ANW-54286; BBL028154; BDBM50327653; LMPK12100008; MFCD00075837; STL372186; AKOS015955887; CCG-339856; MCULE-2789154119; 6,7-dihydroxy-4-phenyl-chromen-2-one; VS-08682; CS-0032642; FT-0698463; ST50309010; SR-01000195708; 2H-1-Benzopyran-2-one, 6,7-dihydroxy-4-phenyl-; SR-01000195708-1
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| Activity |
IC50 = 288000 nM
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[1] | |||
| Compound Name |
6,7-Dihydroxycoumarin-4-acetic Acid
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Investigative | Compound Info | ||
| Synonyms |
6,7-Dihydroxy-4-coumarinylacetic acid; 2-(6,7-dihydroxy-2-oxochromen-4-yl)acetic acid; CHEMBL1255817; 2-(6,7-Dihydroxy-2-oxo-2H-chromen-4-yl)acetic acid; 6,7-DIHYDROXYCOUMARIN-4-ACETICACID; SCHEMBL591195; CTK3E7961; ZINC57799; DTXSID50419825; 6,7-Dihydroxycoumarinyl-4-acetic; BDBM50327652; MFCD01863008; SBB017564; AKOS015894372; FT-0667102; ST50331485; J-100097; 2H-1-Benzopyran-4-aceticacid, 6,7-dihydroxy-2-oxo-; 2H-1-Benzopyran-4-acetic acid, 6,7-dihydroxy-2-oxo-
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| Activity |
IC50 = 335000 nM
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[1] | |||
| Compound Name |
6-Hydroxycoumarin
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Investigative | Compound Info | ||
| Synonyms |
6-Hydroxy-2H-chromen-2-one; 6-hydroxychromen-2-one; 2H-1-Benzopyran-2-one, 6-hydroxy-; 6-hydroxy coumarin; 6-Hydroxycoumaran; 2H-1-Benzopyran-2-one,6-hydroxy-; CHEMBL243263; NSC677227; 6-Hydroxycoumarin, 98%; 6-hydroxycoumarine; 6-Hydroxy-2H-1-benzopyran-2-one; NSC226192; PubChem11099; 6-Hydroxbenzopyran-2-one; 6-Hydroxycoumarin, 96%; 6-hydroxy-chromene-2-one; ACMC-1AY79; SCHEMBL187709; CTK5B2463; 6-Hydroxy-2H-chromen-2-one #; DTXSID70209760; ACT03098; HY-N6656; KS-000014WE; ZINC1757340; ANW-33624; BDBM50327651; KM0450; MFCD00630040; s9364; SBB056309; AKOS005258623; CCG-266293; MCULE-6489847953; NSC-226192; NSC-677227; VZ30776; AS-17834; BR-72788; SC-26678; ST097006; AB0020969; DB-053747; CS-0083182; FT-0635972; V2066; 162056-EP2284170A1; J-518781
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| Activity |
IC50 > 400000 nM
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[1] | |||
| Compound Name |
4-Hydroxycoumarin
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Investigative | Compound Info | ||
| Synonyms |
4-Coumarinol; 4-Hydroxy-2H-chromen-2-one; Benzotetronic acid; 2H-1-BENZOPYRAN-2-ONE, 4-HYDROXY-; Coumarin, 4-hydroxy-; 4-Hydroxy-2H-1-benzopyran-2-one; 4-hydroxychromen-2-one; 4-Hydroxy-chromen-2-one; 4-Hydroxy coumarin; MFCD00006856; 4-HYDROXY-1-BENZOPYRAN-2-ONE; 4-hydroxy-2-chromenone; UNII-X954ZLL2RD; 2-Hydroxychromone; 4-hydroxy-2H-benzo[b]pyran-2-one; 4-Hydroxycoumarin, 98%; 4H-1-Benzopyran-4-one, 2-hydroxy-; X954ZLL2RD; CHEMBL301141; NSC11889; 4-hydroxy-coumarin; EINECS 214-060-2; NSC 11889; BRN 0129768; hydroxychromone; AI3-52393; 4-hyroxycoumarin; 4- Hydroxycoumarin; 4-hydroxyl coumarin; 4-Monohydroxycoumarin; PubChem8693; ACMC-1BO7V; CBiol_000838; WLN: T66 BOVJ EQ; 5-18-01-00378 (Beilstein Handbook Reference); KSC175M9D; MLS004491719; SCHEMBL131312; Coumarin, 4-hydroxy- (8CI); MEGxm0_000452; SCHEMBL1961365; DTXSID8061472; ACon1_001952; CTK0H5691; 4-Hydroxy-2H-chromen-2-one #; DTXSID50944748; HMS1607G02; 4-hydroxy-2-oxo-2H-1-benzopyran; 2-Hydroxy-4H-1-benzopyran-4-one; BCP31120; HY-N6856; STR01861; ANW-15833; BBL027616; BDBM50055710; ICCB4_000134; NSC-11889; SBB038533; STK801816; ZINC18154848; ZINC96006086; AKOS000119142; AKOS037515220; AM84328; DB03410; EBD2035794; LS40467; MCULE-5951606896; NCGC00179970-01; AC-13227; AK-49238; NCI60_000453; SC-00282; SMR000112320; SY001614; AB0004657; DB-014485; BB 0220623; CS-0015925; EU-0066799; FT-0602218; FT-0660645; ST50211285; A-9316; C20414; 4-Hydroxycoumarin, Vetec(TM) reagent grade, 98%; SR-01000389319; J-515519; J-620003; SR-01000389319-1; 4-Hydroxy-2H-1-benzopyran-2-one (4-Hydroxycoumarin); BRD-K48844111-001-01-4; Q25323691; Z56922074; 4-HYDROXY-1-BENZOPYRAN-2-ONE; 4-HYDROXYCOUMARIN; F0266-2972; 4-Hydroxy Coumarin;4-Coumarinol;4-Hydroxy-2H-chromen-2-one
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| Activity |
IC50 > 400000 nM
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| References | Top | ||||
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| REF 1 | 6,7-Dihydroxy-4-phenylcoumarin as inhibitor of aldose reductase 2. Bioorg Med Chem Lett. 2010 Oct 1;20(19):5630-3. | ||||
| REF 2 | Synthesis, activity, and molecular modeling of a new series of tricyclic pyridazinones as selective aldose reductase inhibitors. J Med Chem. 1996 Oct 25;39(22):4396-405. | ||||
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