TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T59445	Sorbitoldehydrogenase	D03KOZ	Epalrestat	Approved	1549120	C15H13NO3S2	319.4	C/C(=C\\C1=CC=CC=C1)/C=C\\2/C(=O)N(C(=S)S2)CC(=O)O	IC50 = 67700 nM	Poor binder
T59445	Sorbitoldehydrogenase	D0Y3DN	Flavonoid derivative 4	Patented	5280343	C15H10O7	302.23	C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O	IC50 = 177000 nM	Poor binder
T59445	Sorbitoldehydrogenase	B5UC6Z	Hymecromone	Investigative	5280567	C10H8O3	176.17	CC1=CC(=O)OC2=C1C=CC(=C2)O	IC50 = 153000 nM	Poor binder
T59445	Sorbitoldehydrogenase	B84OAY	7-Hydroxycoumarin-4-acetic acid	Investigative	5338490	C11H8O5	220.18	C1=CC2=C(C=C1O)OC(=O)C=C2CC(=O)O	IC50 = 163000 nM	Poor binder
T59445	Sorbitoldehydrogenase	BL0Q5S	3-Hydroxycoumarin	Investigative	13650	C9H6O3	162.14	C1=CC=C2C(=C1)C=C(C(=O)O2)O	IC50 = 106000 nM	Poor binder
T59445	Sorbitoldehydrogenase	D02JEZ	7-hydroxycoumarin	Investigative	5281426	C9H6O3	162.14	C1=CC(=CC2=C1C=CC(=O)O2)O	IC50 = 120000 nM	Poor binder
T59445	Sorbitoldehydrogenase	D05QOR	SCOPOLETIN	Investigative	5280460	C10H8O4	192.17	COC1=C(C=C2C(=C1)C=CC(=O)O2)O	IC50 = 137000 nM	Poor binder
T59445	Sorbitoldehydrogenase	D0OC4B	7-Hydroxy-4-phenylcoumarin	Investigative	5357479	C15H10O3	238.24	C1=CC=C(C=C1)C2=CC(=O)OC3=C2C=CC(=C3)O	IC50 = 70700 nM	Poor binder
T59445	Sorbitoldehydrogenase	D0U4BB	HERNIARIN	Investigative	10748	C10H8O3	176.17	COC1=CC2=C(C=C1)C=CC(=O)O2	IC50 = 124000 nM	Poor binder
T59445	Sorbitoldehydrogenase	D0YZ5G	esculetin	Investigative	5281416	C9H6O4	178.14	C1=CC(=O)OC2=CC(=C(C=C21)O)O	IC50 = 82900 nM	Poor binder