Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T36557 | Target Info | |||
| Target Name | Peroxisome proliferator-activated receptor delta (PPARD) | ||||
| Synonyms |
Peroxisomeproliferator-activated receptor beta; Peroxisomeproliferator activated receptor beta/delta; Peroxisome proliferator-activated receptor beta; PPARdelta; PPARB; PPAR-delta; PPAR-beta; Nuclear receptor subfamily 1 group C member 2; Nuclear hormone receptor 1; NUCI; NUC1; NR1C2
Click to Show/Hide
|
||||
| Target Type | Clinical trial Target | ||||
| Gene Name | PPARD | ||||
| Biochemical Class | Nuclear hormone receptor | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 95 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
FENOFIBRIC ACID
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Fenofibric acid; 42017-89-0; Procetofenic acid; 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid; alpha 1081; NSC 281318; LF 178 acid; UNII-BGF9MN2HU1; 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid; LF 153; FNF Acid; C17H15ClO4; Trilipix; CCRIS 7302; EINECS 255-626-9; BGF9MN2HU1; CHEMBL981; BRN 2058973; CHEBI:83469; 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid; Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-; AK117112; 2-{4-[(4-chlorophenyl)carbonyl]phenoxy}-2-methylpropanoic acid; W-106287
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[1] | |||
| Compound Name |
Bezafibrate
Click to Show/Hide
|
Approved | Compound Info | ||
| Synonyms |
Azufibrat; Befibrat; Befizal; BezaLande; BezaPuren; Bezabeta; Bezacur; Bezafibrat; Bezafibrato; Bezafibratum; Bezafisal;Bezalip; Bezamerck; Bezatol; Cedur; Difaterol; Durabezur; Eulitop; Lipox; Reducterol; Sklerofibrat; Solibay; Azupharma Brand of Bezafibrate; Bayer Brand of Bezafibrate; Berlin Chemie Brand of Bezafibrate; Betapharm Brand of Bezafibrate; Beza Lande; Beza Puren; Bezafibrat PB; Bezafibrate Azupharma Brand; Bezafibrate Bayer Brand; Bezafibrate Betapharm Brand; Bezafibrate Cryopharma Brand; Bezafibrate Elfar Brand; Bezafibrate Hennig Brand; Bezafibrate Hexal Brand; Bezafibrate Isis Brand; Bezafibrate Lakeside Brand; Bezafibrate Merckle Brand; Bezafibrate Roche Brand; Bezafibrate Synthelabo Brand; Bezafibrate TAD Brand; Bezafibrate Teva Brand; Bezafibrato [Spanish]; Bezalip Retard; Bezatol SR; Boehringer Mannheim Brand of Bezafibrate; Cryopharma Brand of Bezafibrate; Elfar Brand of Bezafibrate;Hennig Brand of Bezafibrate; Hexal Brand of Bezafibrate; Isis Brand of Bezafibrate; Lakeside Brand of Bezafibrate; Merckle Brand of Bezafibrate; Regadrin B; Roche Brand of Bezafibrate; Synthelabo Brand of Bezafibrate; TAD Brand of Bezafibrate; Teva Brand of Bezafibrate; BM 15075; LO 44; BF-759; BM 15.075; BM-15075; BM15.075; Berlin-Chemie Brand of Bezafibrate; Beza-Lande; Beza-Puren; Bezafibrate Berlin-Chemie Brand; Bezafibrato [INN-Spanish]; Bezafibratum [INN-Latin]; Bezalip (TN); Bezatol SR (TN); PB, Bezafibrat; BM-15.075; Bezafibrate (JP15/USAN/INN); Bezafibrate [USAN:BAN:INN:JAN]; A-[4-(4-chlorobenzoylaminoethyl)phenoxy]isobutyric acid; 2-(4-{2-[(4-chlorobenzoyl)amino]ethyl}phenoxy)-2-methylpropanoic acid; 2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid; 2-[4-(2-[4-Chlorobenzamido]ethyl)-phenoxy]-2-methylpropanoic acid; 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid; 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid; 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid
Click to Show/Hide
|
||||
| Activity |
EC50 = 102000 nM
|
[2] | |||
| Compound Name |
NS-220
Click to Show/Hide
|
Discontinued in Phase 2 | Compound Info | ||
| Synonyms |
R-1593; Cis-2-Methyl-5-[4-[5-methyl-2-(4-methylphenyl)oxazol-4-yl]butyl]-1,3-dioxane-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
(5r)-5-(3-{[3-(6-Methoxy-1,2-Benzoxazol-3-Yl)-2-Oxo-2,3-Dihydro-1h-Benzimidazol-1-Yl]methyl}phenyl)-5-Methyl-1,3-Oxazolidine-2,4-Dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947144; SCHEMBL4950298; BDBM50362954; Q27449900
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(S)-2-(3-((3-(4-Methoxybenzoyl)-2,6-dimethyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL510180; SCHEMBL13959211; BDBM50244656
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(S)-2-(4-Fluoro-3-((6-methoxy-3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL462378; BDBM50244699
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-Methyl-7-[4-(4-phenoxy-2-propyl-phenoxy)-butoxy]-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL110071; SCHEMBL7085299; BDBM50148093; 2-methyl-7-[4-(4-phenoxy-2-propylphenoxy)butoxy]-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(6-methyl-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946753; BDBM50362974
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(2R)-7-(3-(2-Chloro-4-(4-tetrahydropyranyl)phenoxy)propoxy)-2-ethylchromane-2-carboxylic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL179657; SCHEMBL6796429; BDBM50168570; (2R)-7-[3-[2-chloro-4-(oxan-4-yl)phenoxy]propoxy]-2-ethyl-3,4-dihydrochromene-2-carboxylic acid; (R)-7-{3-[2-Chloro-4-(tetrahydro-pyran-4-yl)-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(5-methyl-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946572; BDBM50362973
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
6-(4-(2-Propyl-4-phenoxyphenoxy)butoxy)-2-methyl-chromane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL431450; SCHEMBL7077605; BDBM50148095; 2-Methyl-6-[4-(4-phenoxy-2-propyl-phenoxy)-butoxy]-chroman-2-carboxylic acid; 2-methyl-6-[4-(4-phenoxy-2-propylphenoxy)butoxy]-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(R)-5-[3-(2-Chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL192291; BDBM50171989
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(5R)-5-[3-[[3-(6-Chloro-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947145; SCHEMBL14261747; BDBM50362968
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(S)-2-(4-Fluoro-3-((3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL455127; BDBM50244609
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-Ethyl-7-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy]-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL110743; BDBM50148094
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
7-(3-(2-Propyl-4-(4-chlorophenoxy)phenoxy)propoxy)-2-ethylchromane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111161; SCHEMBL7083301; BDBM50148102; 7-{3-[4-(4-Chloro-phenoxy)-2-propyl-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid; 7-[3-[4-(4-chlorophenoxy)-2-propylphenoxy]propoxy]-2-ethyl-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(2S)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946952; BDBM50362959
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(S)-2-(4-Chloro-3-((6-methoxy-3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL460073; BDBM50244701
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(2R)-2-[5-[[3-(4-Tert-butylphenyl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]-2-chlorophenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946568; BDBM50362951
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(R)-7-[3-(2-Chloro-4-cyclohexyl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL176075; SCHEMBL6792613; BDBM50168544; (2R)-7-[3-(2-chloro-4-cyclohexylphenoxy)propoxy]-2-ethyl-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(S)-2-(4-Chloro-3-((3-(4-chlorophenoxy)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452054; SCHEMBL13959273; BDBM50244611
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-Ethyl-7-{3-[4-(4-fluoro-phenoxy)-2-propyl-phenoxy]-propoxy}-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL111271; SCHEMBL7077858; BDBM50148106; 2-ethyl-7-[3-[4-(4-fluorophenoxy)-2-propylphenoxy]propoxy]-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(S)-2-(4-Chloro-3-((3-(4-chlorophenoxy)-6-fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461378; BDBM50244747
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(5R)-5-[3-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947140; SCHEMBL14261717; BDBM50362965
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-[(4-chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946566; BDBM50362969
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(R)-5-[2-(2-Chloro-4-trifluoromethoxy-phenoxy)-ethoxy]-2-isopropyl-2,3-dihydro-benzofuran-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL363006; SCHEMBL4422445; BDBM50171995
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
2-{3-[1-(4-Methoxy-benzoyl)-2-methyl-5-trifluoromethoxy-1H-indol-3-ylmethyl]-phenoxy}-pentanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL445921; BDBM50157921
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[9] | |||
| Compound Name |
5-Benzyl-2-Ethyl-3-{(1s)-5-[2-(1h-Tetrazol-5-Yl)phenyl]-2,3-Dihydro-1h-Inden-1-Yl}-3,5-Dihydro-4h-Imidazo[4,5-C]pyridin-4-One
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2322437; BDBM50426774; Q27451681; 14R
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
(R)-7-{3-[2-Chloro-4-(4,4-dimethyl-cyclohexyl)-phenoxy]-propoxy}-2-methyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL182200; BDBM50168561
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(4-chlorobenzoyl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946567; BDBM50362970
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(R)-7-[3-(4-Tert-Butyl-2-chloro-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL447190; SCHEMBL6791654; BDBM50168556; (2R)-7-[3-(4-tert-butyl-2-chlorophenoxy)propoxy]-2-ethyl-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
2-Tert-Butyl-5-{3-[2-chloro-4-(2,2,2-trifluoro-ethyl)-phenoxy]-propoxy}-2,3-dihydro-benzofuran-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL363780; SCHEMBL5074973; BDBM50172006
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(R)-2-(3-((3-(4-Methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL452299; BDBM50244557
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(S)-7-{3-[2-Chloro-4-(4-fluoro-phenoxy)-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL109241; SCHEMBL7085851; BDBM50148111
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
6-(3-(2-Propyl-4-phenoxyphenoxy)propoxy)-2-methylchromane-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL114286; SCHEMBL7082264; BDBM50148101; 2-Methyl-6-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy]-chroman-2-carboxylic acid; 2-methyl-6-[3-(4-phenoxy-2-propylphenoxy)propoxy]-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(5R)-5-[4-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947139; BDBM50362964
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
6-[4-(4-Phenoxy-2-propyl-phenoxy)-butoxy]-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL323008; SCHEMBL7079479; BDBM50148091; 6-[4-(4-phenoxy-2-propylphenoxy)butoxy]-3,4-dihydro-2H-chromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946755; BDBM50362955
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(6-chloro-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946570; BDBM50362952
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(2R)-2-[4-Chloro-3-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946953; BDBM50362960
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(S)-2-(2-Chloro-5-((6-chloro-3-(4-chlorophenoxy)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461944; SCHEMBL13959441; BDBM50244750
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethoxy)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946756; BDBM50362956
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(R)-7-[3-(2-Chloro-4-fluoro-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL180123; BDBM50168566
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(R)-7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL179180; SCHEMBL6804503; BDBM50168553
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(2R)-2-[3-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]butanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946955; BDBM50362962
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(2R)-2-[3-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946954; BDBM50362961
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL176222; BDBM50168549
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(5R)-5-[3-[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947141; BDBM50362966
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(S)-2-(2-Chloro-5-((6-methoxy-3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL459466; BDBM50244702
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
CID 11592357
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947142; SCHEMBL4947295; BDBM50362967
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947143; BDBM50362953
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(2R)-2-[4-Chloro-3-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947146; BDBM50362948
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(S)-2-(2-Chloro-5-((3-(4-chlorophenoxy)-6-fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL518499; BDBM50244748
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(5R)-5-[2-[[3-(6-Methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947138; BDBM50362963
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(R)-7-[3-(2-Chloro-4-methoxy-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL360919; BDBM50168562
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
2-Benzyl-5-[3-(2-chloro-4-trifluoromethoxy-phenoxy)-propoxy]-2,3-dihydro-benzofuran-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL192774; BDBM50171987
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
7-[3-(4-Phenoxy-2-propyl-phenoxy)-propoxy]-2-propyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419756; SCHEMBL7081789; BDBM50148109; 7-[3-(4-phenoxy-2-propylphenoxy)propoxy]-2-propyl-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(S)-7-{3-[2-Chloro-4-(2,2,2-trifluoro-ethoxy)-phenoxy]-propoxy}-2-methyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL180928; SCHEMBL6797892; BDBM50168569
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(R)-2-Tert-Butyl-5-[2-(2-chloro-4-trifluoromethoxy-phenoxy)-ethoxy]-2,3-dihydro-benzofuran-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL191489; SCHEMBL4424683; BDBM50171998
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-5-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946757; BDBM50362957
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(S)-2-(2-Fluoro-5-((3-(4-methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL507477; BDBM50244610
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-Ethyl-7-[3-(2-fluoro-4-phenoxy-phenoxy)-propoxy]-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL112973; SCHEMBL7081599; BDBM50148096; 2-ethyl-7-[3-(2-fluoro-4-phenoxyphenoxy)propoxy]-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-Methyl-7-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy]-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL324449; BDBM50148089
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
5-{3-[2-Chloro-4-(2,2-dimethyl-propyl)-phenoxy]-propoxy}-2-ethyl-2,3-dihydro-benzofuran-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL190334; SCHEMBL4681488; BDBM50171997
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[8] | |||
| Compound Name |
(S)-2-(2-Chloro-5-((3-(4-chlorophenoxy)-2-methyl-6-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL517436; BDBM50244808
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(S)-2-(3-((3-(4-Chlorophenoxy)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-4-fluorophenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL509369; BDBM50244654
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(S)-2-(3-((3-(4-Methoxybenzoyl)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)phenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL455126; BDBM50244608
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-Ethyl-7-{3-[4-(4-methoxy-phenoxy)-2-propyl-phenoxy]-propoxy}-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL107991; SCHEMBL7085033; BDBM50148105; 2-ethyl-7-[3-[4-(4-methoxyphenoxy)-2-propylphenoxy]propoxy]-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(5R)-5-[4-Chloro-3-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxobenzimidazol-1-yl]methyl]phenyl]-5-methyl-1,3-oxazolidine-2,4-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1947147; SCHEMBL14261739; BDBM50362949
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(S)-2-(5-((3-(4-Chlorophenoxy)-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-2-fluorophenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL455130; BDBM50244655
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(7-methyl-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946571; BDBM50362972
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
2-Ethyl-7-[3-(4-phenoxy-phenoxy)-propoxy]-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL419019; SCHEMBL7085492; BDBM50148104; 2-ethyl-7-[3-(4-phenoxyphenoxy)propoxy]-3,4-dihydrochromene-2-carboxylic acid
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(S)-2-(5-((3-(4-Chlorophenoxy)-6-fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridin-1-yl)methyl)-2-fluorophenoxy)propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL461379; BDBM50244749
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
(R)-7-[3-(2-Chloro-4-isobutyl-phenoxy)-propoxy]-2-ethyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL179622; SCHEMBL6790498; BDBM50168555
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-5-(trifluoromethoxy)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946758; BDBM50362958
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(6-chloro-1,3-benzothiazol-2-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946569; BDBM50362971
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
(2R)-2-[2-Chloro-5-[[3-(5-chloro-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)benzimidazol-1-yl]methyl]phenoxy]propanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1946754; BDBM50362975
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
2-Ethyl-7-{3-[4-(4-methanesulfonyl-phenoxy)-2-propyl-phenoxy]-propoxy}-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL113324; SCHEMBL7082314; BDBM50148107
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
(R)-7-{3-[2-Chloro-4-(4,4-dimethyl-cyclohexyl)-phenoxy]-propoxy}-2-ethyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL178659; SCHEMBL6796452; BDBM50168550
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
(R)-7-[3-(2-Chloro-4-spiro[2.5]oct-6-yl-phenoxy)-propoxy]-2-methyl-chroman-2-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL178909; BDBM50168568
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[7] | |||
| Compound Name |
Methyleugenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Methyl eugenol; 4-Allyl-1,2-dimethoxybenzene; Eugenol methyl ether; 4-Allylveratrole; O-Methyleugenol; Eugenyl methyl ether; 3,4-Dimethoxyallylbenzene; Methyl eugenol ether; 1,2-Dimethoxy-4-(2-propenyl)benzene; 1-Allyl-3,4-dimethoxybenzene; Veratrole methyl ether; Benzene, 1,2-dimethoxy-4-(2-propenyl)-; Methyl eugenyl ether; 1,2-Dimethoxy-4-allylbenzene; 1,2-dimethoxy-4-prop-2-enylbenzene; 4-allyl-1,2-dimethoxy-benzene; Benzene, 4-allyl-1,2-dimethoxy-; 1,3,4-Eugenol methyl ether; 3-(3,4-dimethoxyphenyl)-1-propene; ENT 21040; 1-(3,4-Dimethoxyphenyl)-2-propene; Eugenol methyl; UNII-29T9VA6R7M; NSC 209528; 4-Allyl-1,2-dimethyoxybenzene; 1,2-dimethoxy-4-(prop-2-en-1-yl)benzene; MFCD00008652; 29T9VA6R7M; Benzene, 1,2-dimethoxy-4-(2-propen-1-yl)-; Benzene, 4-(2-propenyl)-1,2-dimethoxy; DSSTox_CID_5607; 1,4-Eugenol methyl ether; O-Methyl eugenol; DSSTox_RID_77851; DSSTox_GSID_25607; WLN: 1U2R CO1 DO1; Caswell No. 579AB; FEMA Number 2475; Benzene,2-dimethoxy-4-(2-propenyl)-; SMR000112378; CCRIS 746; FEMA No. 2475; Methyleugenol (4-Allyl-1,2-dimethoxybenzene); HSDB 4504; o-Methyl eugenol ether; EINECS 202-223-0; EPA Pesticide Chemical Code 203900; BRN 1910871; 1,2-Dimethoxy-4-(2-propen-1-yl)benzene; AI3-21040; Methyleugenol,(S); Eugenol-methyl ether; Methyl Eugenol Natural; ACMC-209rk6; EC 202-223-0; Allyl-1,2-dimethoxybenzene; MLS001065600; MLS001333205; MLS001333206; SCHEMBL113794; CHEMBL108861; 1,2-Dimethoxy-4-allyl benzene; 4-Allyl-1, 2-dimethoxybenzene; DTXSID5025607; SCHEMBL10108224; CTK3J0502; FEMA 2475; Methyl eugenol, >=98%, FCC; NSC8900; HMS2269M09; HMS3886M22; ZINC388674; Methyl eugenol, analytical standard; HY-N6996; KS-000001JX; NSC-8900; Tox21_202347; Tox21_300071; ANW-39988; BBL027720; BDBM50379791; NSC209528; SBB007916; STK801819; 4-Allyl-1,2-dimethoxybenzene, 99%; AKOS015838877; 1-(3, 4-Dimethoxyphenyl)-2-propene; CS-W017325; NSC-209528; 1, 2-Dimethoxy-4-(2-propenyl)benzene; NCGC00091474-01; NCGC00091474-02; NCGC00091474-03; NCGC00091474-04; NCGC00254085-01; NCGC00259896-01; AK162493; AS-14807; DB-002806; D1360; FT-0626371; S5755; ST50330558; C10454; Q419829; W-100251
Click to Show/Hide
|
||||
| Activity |
EC50 = 50600 nM
|
[11] | |||
| Compound Name |
(2E,4E,8Z)-N-(2-Methylpropyl)dodeca-2,4,8,10-tetraenamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011545; BDBM50379799
Click to Show/Hide
|
||||
| Activity |
EC50 = 51100 nM
|
[11] | |||
| Compound Name |
Pluviatilol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2011539; BDBM50379793; Q15425255
Click to Show/Hide
|
||||
| Activity |
EC50 = 53100 nM
|
[11] | |||
| Compound Name |
2-(2-Methyl-4-((1-(phenylcarbamoyl)isoindolin-2-yl)methyl)phenoxy)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1643197; BDBM50334839
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 60000 nM
|
[12] | |||
| Compound Name |
2-[4-[2-[4-(1,3-Dioxoisoindol-2-yl)phenyl]ethyl]phenoxy]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1813191; BDBM50349839
Click to Show/Hide
|
||||
| Activity |
EC50 = 62000 nM
|
[13] | |||
| Compound Name |
(S)-2-(4-(3-(2-Chloro-4-(2,2,2-trifluoroethyl)phenoxy)propoxy)benzyl)-2-methylbutanoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL206202; BDBM50179840
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 70000 nM
|
[14] | |||
| Compound Name |
Chembl4237449
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL21370574; BDBM50462439
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
(R)-N-(5-Chloro-2-methylphenyl)-2-ethylpiperidine-1-carbothioamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL198082; BDBM50175259
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
N-[4-[4-[3-[1-[(4-Tert-butylphenyl)methyl]-4-ethyl-5-oxo-1,2,4-triazol-3-yl]propyl]phenyl]phenyl]-4-(4-methoxyphenyl)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3264936; BDBM50013725
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[17] | |||
| Compound Name |
(2R)-3,3,3-Trifluoro-2-[5-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylthiophen-2-yl]-2-hydroxypropanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2323021; SCHEMBL3628001; HSD-621; BDBM50426478
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[18] | |||
| Compound Name |
1-(5-Chloro-2-methylphenyl)-3-propylthiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL199938; Thiourea, N-(5-chloro-2-methylphenyl)-N'-propyl-; ACMC-20n5a4; SCHEMBL9053644; CTK0E9020; DTXSID70426298; BDBM50175260; AKOS003713218; N-(2-Methyl-5-chlorophenyl)-N'-propylthiourea
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
Chembl4240338
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL21370444; BDBM50462437
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
(2-Hydroxyethyl)phosphonic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-Hydroxyethylphosphonic acid; 2-Hydroxyethanephosphonic acid; Phosphonic acid, (2-hydroxyethyl)-; 2-hydroxyethyl phosphonic acid; 2-Hydroxyethylphosphonate; CHEMBL1229938; Phosphonic acid,P-(2-hydroxyethyl)-; EINECS 245-370-6; BRN 1751212; Ethephon-hydroxy; SCHEMBL190533; CTK4F0632; (2-Hydroxyethyl)-phosphonic acid; DTXSID70177531; ZINC4097146; BDBM50160407; MFCD00043865; AKOS006283184; Phosphonic acid, P-(2-hydroxyethyl)-; 17-BETA-ESTRADIOL3,17-DIACETATE; FT-0739114; C06451; Ethephon-hydroxy 100 microg/mL in Acetonitrile; Q27105414
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[19] | |||
| Compound Name |
N-(5-Chloro-2-methylphenyl)-N'-(2-methylpropyl)-thiourea
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
HDL376; UNII-B4KLE87R9D; B4KLE87R9D; CHEMBL199418; N-(5-chloro-2-methylphenyl)-N'-(2-methylpropyl)thiourea; SDZ-HDL-376; HDL-376; SCHEMBL9053597; 1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thiourea; BDBM50175261; AKOS003713256; 1-(5-chloro-2-methylphenyl)-3-isobutylthiourea; Thiourea, N-(5-chloro-2-methylphenyl)-N'-(2-methylpropyl)-
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Compound Name |
(S)-N-(5-Chloro-2-methylphenyl)-2-ethylpiperidine-1-carbothioamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL199490; BDBM50175262
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 100000 nM
|
[16] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 68 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
4-[({[4-Ethyl-5-(7-methoxy-1-benzofuran-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetyl)amino]benzoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL491039; ZINC9260679; BDBM50264403; STK136733; AKOS003667785; MCULE-1883110390; 4-(2-(4-ethyl-5-(7-methoxybenzofuran-2-yl)-4H-1,2,4-triazol-3-ylthio)acetamido)benzoic acid
Click to Show/Hide
|
||||
| Activity |
IC50 = 389941.99 nM
|
[20] | |||
| Compound Name |
2-[(1S)-5-{3-[2-Chloro-4-(4H-1,2,4-triazol-4-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220990; SCHEMBL1400260; Indanylacetic Acid Analog, 17w; BDBM21776; 2-[(1S)-5-[3-[2-chloro-4-(1,2,4-triazol-4-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
||||
| Activity |
EC50 = 448435.51 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-{3-[2-Acetamido-4-(1H-1,2,3-triazol-1-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219817; Indanylacetic Acid Analog, 17v; BDBM21775
Click to Show/Hide
|
||||
| Activity |
EC50 = 2724582.73 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(3-Methoxyphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373554; SCHEMBL1400271; Indanylacetic Acid Analog, 17k; BDBM21764
Click to Show/Hide
|
||||
| Activity |
EC50 = 8546730.31 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(3,4-Dimethylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL376537; SCHEMBL1400523; Indanylacetic Acid Analog, 17j; BDBM21762
Click to Show/Hide
|
||||
| Activity |
EC50 = 14924507.21 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(3-Methylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220628; SCHEMBL1400621; Indanylacetic Acid Analog, 17i; BDBM21761
Click to Show/Hide
|
||||
| Activity |
EC50 = 17856650.56 nM
|
[21] | |||
| Compound Name |
2-[4-(3-{[(1S)-1-(Carboxymethyl)-2,3-dihydro-1H-inden-5-yl]oxy}propoxy)-3-propylphenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL222247; SCHEMBL1400267; BDBM21812; Indanylacetic Acid Analog, 34aa
Click to Show/Hide
|
||||
| Activity |
EC50 = 21737019.75 nM
|
[21] | |||
| Compound Name |
2-[4-(3-{[(1S)-1-(Carboxymethyl)-2,3-dihydro-1h-inden-5-yl]oxy}propoxy)-3-methoxyphenyl]-4-methyl-1,3-thiazole-5-carboxylic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL427080; SCHEMBL1400614; BDBM21813; Indanylacetic Acid Analog, 34ab
Click to Show/Hide
|
||||
| Activity |
EC50 = 35719058.25 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-Cyano-2-propylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219661; SCHEMBL1400255; Indanylacetic Acid Analog, 17o; BDBM21768
Click to Show/Hide
|
||||
| Activity |
EC50 = 40003685.1 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-2-propylphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219668; SCHEMBL1400300; Indanylacetic Acid Analog, 34v; BDBM21807
Click to Show/Hide
|
||||
| Activity |
EC50 = 55552038.48 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-Cyano-2-methoxyphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375747; SCHEMBL1400667; Indanylacetic Acid Analog, 17s; BDBM21772
Click to Show/Hide
|
||||
| Activity |
EC50 = 71433182.62 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(Trifluoromethoxy)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[4-(trifluoromethoxy)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL373605; SCHEMBL1400262; Indanylacetic Acid Analog, 17d; BDBM21756
Click to Show/Hide
|
||||
| Activity |
EC50 = 76930755.95 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-{3-[4-(Pyrimidin-5-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220448; SCHEMBL1400268; Indanylacetic Acid Analog, 29f; BDBM21763; 2-[(1S)-5-[3-(4-pyrimidin-5-ylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
||||
| Activity |
EC50 = 90907559.74 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Tert-butyl-1,3-thiazol-2-yl)-2-propylphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220117; SCHEMBL1400351; Indanylacetic Acid Analog, 34g; BDBM21792
Click to Show/Hide
|
||||
| Activity |
EC50 = 90907559.74 nM
|
[21] | |||
| Compound Name |
((1S)-5-{3-[4-(4-Ethyl-1,3-thiazol-2-yl)-2-propylphenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl)acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373813; SCHEMBL3023128; Indanylacetic Acid Analog, 34e; BDBM21790
Click to Show/Hide
|
||||
| Activity |
EC50 = 90907559.74 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-{3-[4-(1H-1,2,4-Triazol-1-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220431; Indanylacetic Acid Analog, 17u; BDBM21774
Click to Show/Hide
|
||||
| Activity |
EC50 = 90907559.74 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-Ethylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220421; SCHEMBL1400619; Indanylacetic Acid Analog, 17b; BDBM21754
Click to Show/Hide
|
||||
| Activity |
EC50 = 112359552.3 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(2-Methoxy-4-methylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220060; SCHEMBL1400278; Indanylacetic Acid Analog, 17q; BDBM21770
Click to Show/Hide
|
||||
| Activity |
EC50 = 133333721.2 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-Cyanophenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220508; SCHEMBL1400780; Indanylacetic Acid Analog, 17g; BDBM21759
Click to Show/Hide
|
||||
| Activity |
EC50 = 136987203.5 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL374545; SCHEMBL1400856; Indanylacetic Acid Analog, 34u; BDBM21806
Click to Show/Hide
|
||||
| Activity |
EC50 = 144927232.8 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-Methoxyphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220627; SCHEMBL1400338; Indanylacetic Acid Analog, 17e; BDBM21757
Click to Show/Hide
|
||||
| Activity |
EC50 = 149255381.9 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-Ethoxyphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220507; SCHEMBL1400700; Indanylacetic Acid Analog, 17f; BDBM21758
Click to Show/Hide
|
||||
| Activity |
EC50 = 151516524.5 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Ethoxy-5-methyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220152; SCHEMBL1400686; BDBM21824; Indanylacetic Acid Analog, 34am
Click to Show/Hide
|
||||
| Activity |
EC50 = 166667146.5 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-{3-[4-(Thiophen-3-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375748; SCHEMBL1400569; Indanylacetic Acid Analog, 29a; BDBM21778
Click to Show/Hide
|
||||
| Activity |
EC50 = 169492310.5 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(2,4-Dimethoxypyrimidin-5-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[4-(2,4-dimethoxypyrimidin-5-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL425116; SCHEMBL1400636; Indanylacetic Acid Analog, 29g; BDBM21783
Click to Show/Hide
|
||||
| Activity |
EC50 = 178574729.1 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Ethoxy-5-ethyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219609; SCHEMBL1400824; BDBM21825; Indanylacetic Acid Analog, 34an
Click to Show/Hide
|
||||
| Activity |
EC50 = 185186788.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(1,3-Benzothiazol-2-yl)-2-methoxyphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL424939; SCHEMBL1400421; Indanylacetic Acid Analog, 34t; BDBM21805
Click to Show/Hide
|
||||
| Activity |
EC50 = 192309172.9 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-(3-{4-[4-(Carboxymethyl)-1,3-thiazol-2-yl]-2-propylphenoxy}propoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375072; SCHEMBL3120428; BDBM21815; Indanylacetic Acid Analog, 34ad
Click to Show/Hide
|
||||
| Activity |
EC50 = 217390219 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(2,4-Dimethylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220785; SCHEMBL3019471; Indanylacetic Acid Analog, 17l; BDBM21765
Click to Show/Hide
|
||||
| Activity |
EC50 = 217395224.6 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Ethyl-1,3-thiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[4-(4-ethyl-1,3-thiazol-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL220635; SCHEMBL1400693; Indanylacetic Acid Analog, 34d; BDBM21789
Click to Show/Hide
|
||||
| Activity |
EC50 = 227274127.9 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-(3-{4-[5-(Dimethylcarbamoyl)-4-methyl-1,3-thiazol-2-yl]-2-propylphenoxy}propoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220662; SCHEMBL1400162; Indanylacetic Acid Analog, 34x; BDBM21809
Click to Show/Hide
|
||||
| Activity |
EC50 = 227274127.9 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(Trifluoromethyl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[4-(trifluoromethyl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL220422; SCHEMBL1400241; Indanylacetic Acid Analog, 17c; BDBM21755
Click to Show/Hide
|
||||
| Activity |
EC50 = 238094849.1 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-{4H,5H,6H-Cyclopenta[d][1,3]thiazol-2-yl}-2-methoxyphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL222248; SCHEMBL1400371; Indanylacetic Acid Analog, 34n; BDBM21799
Click to Show/Hide
|
||||
| Activity |
EC50 = 243904605 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(2-Propyl-4-{5H,6H,7H-pyrano[2,3-d][1,3]thiazol-2-yl}phenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1400218; CHEMBL2236890; Indanylacetic Acid Analog, 34r; BDBM21803
Click to Show/Hide
|
||||
| Activity |
EC50 = 249999995 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4,5-Dimethyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL374925; SCHEMBL1400962; Indanylacetic Acid Analog, 34k; BDBM21796
Click to Show/Hide
|
||||
| Activity |
EC50 = 250005751.5 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(Furan-3-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[4-(furan-3-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL376418; SCHEMBL1400869; Indanylacetic Acid Analog, 29b; BDBM21779
Click to Show/Hide
|
||||
| Activity |
EC50 = 263160074.1 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-{4H,5H,6H-Cyclopenta[d][1,3]thiazol-2-yl}-2-propylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220223; SCHEMBL3117156; Indanylacetic Acid Analog, 34m; BDBM21798
Click to Show/Hide
|
||||
| Activity |
EC50 = 285739315.5 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220151; SCHEMBL1400676; Indanylacetic Acid Analog, 34w; BDBM21808
Click to Show/Hide
|
||||
| Activity |
EC50 = 294116913.7 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Ethoxy-1,3-thiazol-2-yl)-2-methoxyphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220894; SCHEMBL1400468; BDBM21820; Indanylacetic Acid Analog, 34ai
Click to Show/Hide
|
||||
| Activity |
EC50 = 294116913.7 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-(3-{2-Methyl-4-[3-(trifluoromethyl)-1,2,4-thiadiazol-5-yl]phenoxy}propoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219688; SCHEMBL1400498; Indanylacetic Acid Analog, 17x; BDBM21777
Click to Show/Hide
|
||||
| Activity |
EC50 = 294123686 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-(3-{2-Propyl-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]phenoxy}propoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL374090; SCHEMBL1400786; Indanylacetic Acid Analog, 34h; BDBM21793
Click to Show/Hide
|
||||
| Activity |
EC50 = 303033052.1 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[2-Methoxy-4-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219617; SCHEMBL1400681; Indanylacetic Acid Analog, 34q; BDBM21802
Click to Show/Hide
|
||||
| Activity |
EC50 = 303033052.1 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Ethoxy-5-methyl-1,3-thiazol-2-yl)-2-propylphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL373791; SCHEMBL1400704; BDBM21823; Indanylacetic Acid Analog, 34al
Click to Show/Hide
|
||||
| Activity |
EC50 = 312499984.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[2-Methoxy-4-(4-methoxy-1,3-thiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL222508; SCHEMBL1400402; BDBM21817; Indanylacetic Acid Analog, 34af
Click to Show/Hide
|
||||
| Activity |
EC50 = 333334296.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-(3-{2-Methoxy-4-[4-(propan-2-yloxy)-1,3-thiazol-2-yl]phenoxy}propoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219669; SCHEMBL1400978; BDBM21822; Indanylacetic Acid Analog, 34ak
Click to Show/Hide
|
||||
| Activity |
EC50 = 333334296.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-(3-{2-Methoxy-4-[4-(trifluoromethyl)-1,3-thiazol-2-yl]phenoxy}propoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219687; SCHEMBL1400842; Indanylacetic Acid Analog, 34i; BDBM21794
Click to Show/Hide
|
||||
| Activity |
EC50 = 344825996.6 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4,5-Dimethyl-1,3-thiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220837; SCHEMBL1400266; Indanylacetic Acid Analog, 34j; BDBM21795
Click to Show/Hide
|
||||
| Activity |
EC50 = 344833936.6 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[2-Methoxy-4-(4-methyl-1,3-thiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220059; SCHEMBL1400323; Indanylacetic Acid Analog, 34c; BDBM21788
Click to Show/Hide
|
||||
| Activity |
EC50 = 370373580.5 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-Ethyl-2-methoxyphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220681; SCHEMBL1400818; Indanylacetic Acid Analog, 17r; BDBM21771
Click to Show/Hide
|
||||
| Activity |
EC50 = 370373580.5 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Ethyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220557; SCHEMBL1400349; Indanylacetic Acid Analog, 34f; BDBM21791
Click to Show/Hide
|
||||
| Activity |
EC50 = 400000008 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(2-Propylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375098; SCHEMBL3019309; Indanylacetic Acid Analog, 17m; BDBM21766
Click to Show/Hide
|
||||
| Activity |
EC50 = 416667858 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-{3-[4-(Pyridin-3-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL219944; SCHEMBL1400495; Indanylacetic Acid Analog, 29d; BDBM21781; 2-[(1S)-5-[3-(4-pyridin-3-ylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
||||
| Activity |
EC50 = 434780442.3 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-(3-{4-[4-(Propan-2-yloxy)-1,3-thiazol-2-yl]-2-propylphenoxy}propoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL436514; SCHEMBL1400496; BDBM21821; Indanylacetic Acid Analog, 34aj
Click to Show/Hide
|
||||
| Activity |
EC50 = 434780442.3 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4,5,6,7-Tetrahydro-1,3-benzothiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375812; SCHEMBL1400287; Indanylacetic Acid Analog, 34o; BDBM21800
Click to Show/Hide
|
||||
| Activity |
EC50 = 454548260.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(2-Ethoxy-4-methylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220430; SCHEMBL1400329; Indanylacetic Acid Analog, 17t; BDBM21773
Click to Show/Hide
|
||||
| Activity |
EC50 = 454548260.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-{3-[4-(6-Methylpyridin-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220325; SCHEMBL1400382; Indanylacetic Acid Analog, 29h; BDBM21784
Click to Show/Hide
|
||||
| Activity |
EC50 = 454548260.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-(3-{4-[5-(Dimethylcarbamoyl)-4-methyl-1,3-thiazol-2-yl]-2-methoxyphenoxy}propoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220173; SCHEMBL1400660; Indanylacetic Acid Analog, 34y; BDBM21810
Click to Show/Hide
|
||||
| Activity |
EC50 = 476189702.9 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Ethoxy-1,3-thiazol-2-yl)-2-propylphenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL387350; SCHEMBL1400331; BDBM21819; Indanylacetic Acid Analog, 34ah
Click to Show/Hide
|
||||
| Activity |
EC50 = 499999995 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-Phenoxy-2-propylphenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL220836; SCHEMBL1400679; Indanylacetic Acid Analog, 17p; BDBM21769
Click to Show/Hide
|
||||
| Activity |
EC50 = 526320153.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[2-Propyl-4-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL1400467; CHEMBL2113263; Indanylacetic Acid Analog, 34p; BDBM21801
Click to Show/Hide
|
||||
| Activity |
EC50 = 526320153.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[2-Methoxy-4-(1,3-thiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[2-methoxy-4-(1,3-thiazol-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL220124; SCHEMBL1400868; Indanylacetic Acid Analog, 34b; BDBM21787
Click to Show/Hide
|
||||
| Activity |
EC50 = 580002679.6 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[2-Propyl-4-(trifluoromethyl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[2-propyl-4-(trifluoromethyl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL219686; SCHEMBL1400334; Indanylacetic Acid Analog, 17n; BDBM21767
Click to Show/Hide
|
||||
| Activity |
EC50 = 624999975 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[2-Propyl-4-(1,3-thiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[2-propyl-4-(1,3-thiazol-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL374901; SCHEMBL1400247; Indanylacetic Acid Analog, 34a; BDBM21786
Click to Show/Hide
|
||||
| Activity |
EC50 = 624999975 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(1H-Indol-6-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[4-(1H-indol-6-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL220893; SCHEMBL1400787; Indanylacetic Acid Analog, 29c; BDBM21780
Click to Show/Hide
|
||||
| Activity |
EC50 = 666668599.4 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(4-{4H,5H,6H-Cyclopenta[d][1,3]thiazol-2-yl}phenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL221101; SCHEMBL3122256; Indanylacetic Acid Analog, 34l; BDBM21797
Click to Show/Hide
|
||||
| Activity |
EC50 = 769236706.9 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Methoxy-1,3-thiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[4-(4-methoxy-1,3-thiazol-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL220224; SCHEMBL1400374; BDBM21816; Indanylacetic Acid Analog, 34ae
Click to Show/Hide
|
||||
| Activity |
EC50 = 769236706.9 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-(2-Methoxy-4-{5H,6H,7H-pyrano[2,3-d][1,3]thiazol-2-yl}phenoxy)propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL375427; Indanylacetic Acid Analog, 34s; BDBM21804
Click to Show/Hide
|
||||
| Activity |
EC50 = 769236706.9 nM
|
[21] | |||
| Compound Name |
2-[(1S)-5-[3-[4-(4-Ethoxy-1,3-thiazol-2-yl)phenoxy]propoxy]-2,3-dihydro-1H-inden-1-yl]acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
2-[(1S)-5-{3-[4-(4-ethoxy-1,3-thiazol-2-yl)phenoxy]propoxy}-2,3-dihydro-1H-inden-1-yl]acetic acid; CHEMBL223748; SCHEMBL1400573; BDBM21818; Indanylacetic Acid Analog, 34ag
Click to Show/Hide
|
||||
| Activity |
EC50 = 833333805.5 nM
|
[21] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonists. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2128-32. | ||||
| REF 2 | Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity. J Med Chem. 2002 Feb 14;45(4):789-804. | ||||
| REF 3 | Structure-activity studies on 1,3-dioxane-2-carboxylic acid derivatives, a novel class of subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonists. Bioorg Med Chem. 2008 Jan 15;16(2):981-94. | ||||
| REF 4 | Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor (PPAR) modulators. J Med Chem. 2011 Dec 22;54(24):8541-54. | ||||
| REF 5 | Highly functionalized 7-azaindoles as selective PPAR gamma modulators. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4798-801. | ||||
| REF 6 | (2R)-2-ethylchromane-2-carboxylic acids: discovery of novel PPARalpha/gamma dual agonists as antihyperglycemic and hypolipidemic agents. J Med Chem. 2004 Jun 3;47(12):3255-63. | ||||
| REF 7 | (2R)-2-methylchromane-2-carboxylic acids: discovery of selective PPARalpha agonists as hypolipidemic agents. Bioorg Med Chem Lett. 2005 Jul 15;15(14):3347-51. | ||||
| REF 8 | Novel 2,3-dihydrobenzofuran-2-carboxylic acids: highly potent and subtype-selective PPARalpha agonists with potent hypolipidemic activity. J Med Chem. 2005 Aug 25;48(17):5589-99. | ||||
| REF 9 | Benzoyl 2-methyl indoles as selective PPARgamma modulators. Bioorg Med Chem Lett. 2005 Jan 17;15(2):357-62. | ||||
| REF 10 | Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-. Bioorg Med Chem Lett. 2013 Feb 1;23(3):767-72. | ||||
| REF 11 | Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldii. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2527-33. | ||||
| REF 12 | Discovery of isoindoline and tetrahydroisoquinoline derivatives as potent, selective PPAR agonists. Bioorg Med Chem Lett. 2011 Jan 1;21(1):492-6 | ||||
| REF 13 | Peroxisome proliferator-activated receptor agonists with phenethylphenylphthalimide skeleton derived from thalidomide-related liver X receptor antagonists: relationship between absolute configuration and subtype selectivity. Bioorg Med Chem. 2011 May 15;19(10):3156-72. | ||||
| REF 14 | Design and synthesis of potent and subtype-selective PPARalpha agonists. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1673-8. | ||||
| REF 15 | Structure-guided evolution of a 2-phenyl-4-carboxyquinoline chemotype into PPARalpha selective agonists: New leads for oculovascular conditions. Bioorg Med Chem Lett. 2018 Sep 1;28(16):2717-2722. | ||||
| REF 16 | Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents. Bioorg Med Chem Lett. 2006 Jan 1;16(1):113-7. | ||||
| REF 17 | Identification of the first potent, selective and bioavailable PPARalpha antagonist. Bioorg Med Chem Lett. 2014 May 15;24(10):2267-72. | ||||
| REF 18 | Discovery of HSD-621 as a Potential Agent for the Treatment of Type 2 Diabetes. ACS Med Chem Lett. 2012 Nov 23;4(1):118-23. | ||||
| REF 19 | Pharmacophore elucidation of phosphoiodyn A - Potent and selective peroxisome proliferator-activated receptor / agonists with neuroprotective activity. Bioorg Med Chem Lett. 2016 Apr 15;26(8):1889-93. | ||||
| REF 20 | Activity landscape modeling of PPAR ligands with dual-activity difference maps. Bioorg Med Chem. 2012 Jun 1;20(11):3523-32. | ||||
| REF 21 | Common binding requirements of PPAR-alpha/delta/gamma pan agonists: quantitative structure-activity relationship analysis of indanylacetic acid derivatives carrying 4-thiazolyl-phenoxy tail group. Med Chem Res. 2011 Feb 20;21:891-907. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.