Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T16042 | Target Info | |||
| Target Name | Arachidonate 15-lipoxygenase (15-LOX) | ||||
| Synonyms |
LOG15; Arachidonate omega-6 lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type; 15-Lipoxygenase; 15-LOX-1; 12/15-lipoxygenase; 12-LOX
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| Target Type | Patented-recorded Target | ||||
| Gene Name | ALOX15 | ||||
| Biochemical Class | Oxygenase | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 117 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
NSC-292213
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Investigative | Compound Info | ||
| Synonyms |
NSC-292213; NSC292213; CHEMBL222808; AC1L8B2I; NCIStruc2_001766; NCIStruc1_001644; ZINC1565922; NCI292213; BDBM50158387; NCGC00014649; CCG-37867; NCGC00014649-02; NCGC00097752-01; NCI60_002407; 4-[(3-carboxy-4-hydroxy-1-naphthyl)(oxo)acetyl]-1-hydroxy-2-naphthoic acid; 4-[2-(3-carboxy-4-hydroxy-naphthalen-1-yl)-2-oxo-acetyl]-1-hydroxy-naphthalene-2-carboxylic acid; 4-[2-(3-carboxy-4-hydroxynaphthalen-1-yl)-2-oxoacetyl]-1-hydroxynaphthalene-2-carboxylic acid
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
NSC-94258
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Investigative | Compound Info | ||
| Synonyms |
7-Hydroxyflavone; 6665-86-7; 7-Hydroxy-2-phenyl-4H-chromen-4-one; Flavone, 7-hydroxy-; 7-Hydroxy-2-phenyl-4-benzopyrone; 4H-1-Benzopyran-4-one, 7-hydroxy-2-phenyl-; 7-hydroxy-2-phenylchromen-4-one; 4H-1-Benzopyran-4-one, 7-hydroxy-; 7-Hydroxy-2-phenyl-chromen-4-one; NSC 94258; UNII-ZE72458E4L; EINECS 229-705-3; NSC-94258; MLS002695239; CHEBI:2268; CHEMBL276915; MQGPSCMMNJKMHQ-UHFFFAOYSA-N; ZE72458E4L; NSC94258; MFCD00006835; 7-Hydroxy-2-phenyl-4H-1-benzopyran-4-one; H-5100; SR-01000359106; 7-Hydroxyflavone, 11; 7-Hydroxy-flavone,
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| Activity |
IC50 ~ 100000 nM
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[2] | |||
| Compound Name |
2-bromophenol
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Investigative | Compound Info | ||
| Synonyms |
2-BROMOPHENOL; 95-56-7; o-Bromophenol; Phenol, 2-bromo-; BROMOPHENOL; 2-Bromfenol; 2-Bromo-phenol; Phenol, o-bromo-; o-bromo-phenol; 2-bromo phenol; Phenol, bromo-; 2-Bromfenol [Czech]; NSC 6970; bromophenol, 2-; UNII-A0UB206YF0; 2-Bromophenol, 98%; EINECS 202-432-7; 1-Bromo-2-hydroxybenzene; BRN 1905115; CHEMBL186007; A0UB206YF0; 2-BROMO-1-HYDROXYBENZENE; VADKRMSMGWJZCF-UHFFFAOYSA-N; MFCD00002146; 32762-51-9; ortho-bromophenol; 2BR; bromphenol; bromo-phenol; bromo phenol; 2-bromanylphenol; HSDB 7648; ortho-bromo-phenol; EINECS 251-200-1
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| Activity |
IC50 ~ 100000 nM
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[3] | |||
| Compound Name |
3,7-dihydroxy-flavone
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Investigative | Compound Info | ||
| Synonyms |
3,7-dihydroxyflavone; 7-Hydroxyflavonol; 492-00-2; 3,7-dihydroxy-2-phenyl-4H-chromen-4-one; 5-Deoxygalangin; 4H-1-Benzopyran-4-one, 3,7-dihydroxy-2-phenyl-; UNII-O948D0K9BQ; O948D0K9BQ; CHEMBL210276; 3,7-dihydroxy-2-phenylchromen-4-one; 3,7-dihydroxy-flavone; 7,3'-dihydroxyflavonol; SR-01000314616; Resogalangin; SPBio_001803; Spectrum_001462; SpecPlus_000778; AC1NU2BD; Spectrum4_001767; Spectrum3_001623; Spectrum2_001652; Spectrum5_000353; 3,7-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one; Oprea1_793720; KBioSS_001942; KBioGR_002253
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| Activity |
IC50 ~ 100000 nM
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[2] | |||
| Compound Name |
5-(Methylamino)-2-naphthalen-1-yl-1,3-thiazole-4-carbonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3262925; NCGC00319032-01; SCHEMBL16515732; BDBM50011783
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
5-Methoxy-2-[5-(4-methylphenyl)-1H-pyrazol-3-yl]phenol
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Investigative | Compound Info | ||
| Synonyms |
GNF-Pf-4068; MLS001197234; CHEMBL584668; SMR000555471; Oprea1_080418; SCHEMBL3484048; BDBM58482; cid_5414911; REGID_for_CID_5414911; HMS2886A17; BDBM50148010; CCG-17911; STL069602; ZINC13126403; AKOS000662796; MCULE-8609365028; SR-01000455068; SR-01000455068-1; (6Z)-3-methoxy-6-[5-(p-tolyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one
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| Activity |
IC50 ~ 50000 nM
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[5] | |||
| Compound Name |
2-Amino-5-(4-bromophenyl)-N-butylthiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3944748
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
2-Amino-N-butyl-5-(4-chlorophenyl)thiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3980129
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
2-Amino-N,4-dibutyl-5-phenylthiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3962223; BDBM50206320
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
4-[(2-Hydroxy-3-methoxyphenyl)methylamino]-N-(1,3-thiazol-2-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1596118; SMR000072364; MLS000088134; SCHEMBL16646082; HMS2401E17; ZINC793995; BDBM50447178; STK806487; AKOS000505685; MCULE-3112730599; NCGC00059191-02; NCGC00059191-03; EU-0048240; MLS000088134-02; 4-[(2-hydroxy-3-methoxybenzyl)amino]-N-1,3-thiazol-2-ylbenzenesulfonamide; N-(2-Thiazolyl)-4-(2-hydroxy-3-methoxybenzylamino)benzenesulfonamide; 4-[(2-hydroxy-3-methoxybenzyl)amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide; 4-[[(2-Hydroxy-3-methoxyphenyl)methyl]amino]-N-2-thiazolyl-benzenesulfonamide
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| Activity |
IC50 ~ 50000 nM
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[7] | |||
| Compound Name |
2-Amino-N-butyl-5-pentylthiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3924575
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
2-(3,4-Dichlorophenyl)-5-(methylamino)-1,3-oxazole-4-carbonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3262909; SCHEMBL16515745; BDBM50011736; NCGC00262512-01
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| Activity |
IC50 ~ 50000 nM
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[4] | |||
| Compound Name |
2-Amino-5-phenyl-N-(4-phenylbutyl)thiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3943550
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
(5E)-N-Benzyl-5-(3-methyl-6-oxocyclohexa-2,4-dien-1-ylidene)-1,2-dihydropyrazole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
MLS000551826; SMR000145751; 5-(2-Hydroxy-5-methyl-phenyl)-2H-pyrazole-3-carboxylic acid benzylamide; CHEMBL1611217; BDBM59267; cid_6097793; HMS2546D21; STK577884; ZINC13121830; AKOS002201205; AKOS005502275; MCULE-5372231968; N-benzyl-5-(2-hydroxy-5-methylphenyl)-1H-pyrazole-3-carboxamide
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| Activity |
IC50 ~ 50000 nM
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[5] | |||
| Compound Name |
(3,7,11-Trimethyl-2,6,10-dodecatrienyl)phenyl ether
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL2088237; Farnesyl Phenyl Ether; BDBM50391179
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
5-(Methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile
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Investigative | Compound Info | ||
| Synonyms |
ML351; ML 351; MLS000082299; 5-(methylamino)-2-naphthalen-1-yl-1,3-oxazole-4-carbonitrile; 5-(methylamino)-2-(naphthalen-1-yl)-1,3-oxazole-4-carbonitrile; 5-Methylamino-2-naphthalen-1-yl-oxazole-4-carbonitrile; 5-(Methylamino)-2-(naphthalen-1-yl)oxazole-4-carbonitrile; SMR000045344; MLS004813835; cid_664510; CHEMBL1548353; SCHEMBL16515652; BDBM79800; GTPL10263; HMS2156P03; HMS3313H01; REGID_FOR_CID_664510; ZINC542135; MFCD04183120; STK905505; AKOS005183681; MCULE-5030858957; NCGC00070329-02; NCGC00070329-03; ML351, >=98% (HPLC); ST45252961; A1-18402; 2-(1-Naphthyl)-5-(methylamino)oxazole-4-carbonitrile; 5-(methylamino)-2-(1-naphthyl)oxazole-4-carbonitrile; 5-(methylamino)-2-naphthyl-1,3-oxazole-4-carbonitrile; Z1213743771; 5-(methylamino)-2-(1-naphthyl)-1,3-oxazol-4-yl cyanide
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| Activity |
IC50 ~ 50000 nM
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[4] | |||
| Compound Name |
2-Amino-N-butyl-4-methyl-5-phenylthiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3935807; BDBM50206317
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
2-Amino-N-butyl-5-ethylthiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3933498
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
4-Bromo-2-[5-(2-chlorophenyl)-1H-pyrazol-3-yl]phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1546898; MLS000778281; SCHEMBL10357372; HMS2751A13; BDBM50147981; STK557344; ZINC13126309; AKOS002181964; MCULE-5017674645; SMR000415075; ST50070872; 4-bromo-2-[5-(2-chlorophenyl)pyrazol-3-yl]phenol; 4-Bromo-2-[5-(2-chloro-phenyl)-1H-pyrazol-3-yl]-phenol; 4-Bromo-2-[5-(2-chlorophenyl)-1H-pyrazole-3-yl]phenol
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| Activity |
IC50 ~ 50000 nM
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[5] | |||
| Compound Name |
3-[(2E,6E)-3,7,11-Trimethyldodeca-2,6,10-trienoxy]chromen-2-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1834532; BDBM50391174
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| Activity |
IC50 ~ 50000 nM
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[8] | |||
| Compound Name |
N-[(8-Hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]propanamide
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Investigative | Compound Info | ||
| Synonyms |
MLS000714362; SMR000274342; Oprea1_336993; Oprea1_793179; SCHEMBL2598266; CHEMBL1370513; BDBM65361; cid_3136123; HMS2691F18; AKOS000539049; NCGC00182903-03; SR-01000360535; SR-01000360535-1; N-[(8-hydroxy-7-quinolyl)-(2-thienyl)methyl]propionamide; N-[(8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]propanamide; N-[(8-oxidanylquinolin-7-yl)-thiophen-2-yl-methyl]propanamide
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| Activity |
IC50 ~ 50000 nM
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[9] | |||
| Compound Name |
N-[(5-Chloro-8-hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]propanamide
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Investigative | Compound Info | ||
| Synonyms |
MLS000714585; SMR000274564; BAS 01923195; Oprea1_179687; Oprea1_779522; SCHEMBL609894; CHEMBL1405150; BDBM64651; cid_3136134; HMS2674N10; AKOS000539018; NCGC00182957-03; NCGC00182957-04; NCGC00188867-01; NCGC00188868-01; SR-01000361829; SR-01000361829-1; N-[(5-chloro-8-hydroxy-7-quinolyl)-(2-thienyl)methyl]propanamide; N-[(5-chloro-8-hydroxy-7-quinolyl)-(2-thienyl)methyl]propionamide; N-[(5-chloranyl-8-oxidanyl-quinolin-7-yl)-thiophen-2-yl-methyl]propanamide; N-[(5-chloro-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]propanamide
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| Activity |
IC50 ~ 50000 nM
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[9] | |||
| Compound Name |
N-(3-(2-Methoxybenzamido)phenyl)thiophene-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL381113; Cambridge id 6712889; Oprea1_861177; MLS001206985; HMS2837B08; ZINC780710; BDBM50182509; STK390346; Thiophene-2-carboxylic acid [3-(2-methoxy-benzoylamino)-phenyl]-amide; AKOS000595757; MCULE-4291013618; SMR000519009; ST50274667; AB00117089-01; (2-methoxyphenyl)-N-[3-(2-thienylcarbonylamino)phenyl]carboxamide; N-(3-{[(2-methoxyphenyl)carbonyl]amino}phenyl)thiophene-2-carboxamide
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| Activity |
IC50 ~ 50000 nM
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[10] | |||
| Compound Name |
N-[(5-Chloro-8-hydroxyquinolin-7-yl)-(furan-2-yl)methyl]propanamide
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Investigative | Compound Info | ||
| Synonyms |
TCMDC-123650; MLS000713956; SMR000273437; ChemDiv3_003931; Cambridge id 6955265; Oprea1_392575; Oprea1_876567; SCHEMBL609251; CHEMBL580727; BDBM64674; cid_2920571; HMS1484C15; HMS2626D19; CCG-21589; IDI1_021841; NCGC00179686-01; NCGC00179686-04; NCGC00179686-06; SJ000032162; SR-01000503652; SR-01000503652-1; BRD-A10105593-001-01-3; N-[(5-chloro-8-hydroxy-7-quinolinyl)-(2-furanyl)methyl]propanamide; N-[(5-chloro-8-hydroxy-7-quinolyl)-(2-furyl)methyl]propanamide; N-[(5-chloro-8-hydroxy-7-quinolyl)-(2-furyl)methyl]propionamide; N-[(5-chloranyl-8-oxidanyl-quinolin-7-yl)-(furan-2-yl)methyl]propanamide
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| Activity |
IC50 ~ 50000 nM
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[9] | |||
| Compound Name |
N-(3-(2-Methylbenzamido)phenyl)thiophene-2-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL202582; Oprea1_623197; MLS001206558; HMS2814A10; ZINC884414; BDBM50182510; STK259254; Thiophene-2-carboxylic acid [3-(2-methyl-benzoylamino)-phenyl]-amide; ZINC00884414; AKOS000461241; MCULE-9039046377; SMR000517906; ST50267492; AB00116817-01; SR-01000365943; SR-01000365943-1; (2-methylphenyl)-N-[3-(2-thienylcarbonylamino)phenyl]carboxamide; N-(3-{[(2-methylphenyl)carbonyl]amino}phenyl)thiophene-2-carboxamide
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| Activity |
IC50 ~ 50000 nM
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[10] | |||
| Compound Name |
2-Amino-N,4-dibutyl-5-(4-chlorophenyl)thiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3902172; BDBM50206309
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
2-(1H-Pyrazol-3-yl)phenol
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Investigative | Compound Info | ||
| Synonyms |
2-(1H-pyrazol-5-yl)phenol; 2-(Pyrazol-5-yl)phenol; 3-(2-hydroxyphenyl)pyrazole; Phenol, 2-(1H-pyrazol-3-yl)-; CHEMBL503606; 3-(2-Hydroxyphenyl)-1H-pyrazole; 6-(1,2-dihydropyrazol-3-ylidene)cyclohexa-2,4-dien-1-one; o-(1H-Pyrazol-3-yl)phenol; pyrazole, 32; EINECS 252-222-4; 2-pyrazol-3-ylphenol; MLS002473395; SCHEMBL206363; 5-(2'-hydroxyphenyl)pyrazole; 2-(1H-Pyrazole-5-yl)phenol; 2-(1H-pyrazol-3-yl) phenol; BDBM24679; cid_5409210; CTK1C4330; CTK8A0247; HMS2217K14; HMS3349D03; (6Z)-6-(1,2-dihydropyrazol-3-ylidene)cyclohexa-2,4-dien-1-one; ACT07627; 4750AH; ANW-27976; MFCD03093876; SBB087437; ZINC12958528; 2-(1H-Pyrazol-3-yl)phenol, 97%; AKOS006240472; MCULE-1960882999; NCGC00247411-01; AS-48265; SMR001397487; P2218; EN300-55848; A-7973; J-019769; (6Z)-6-(3-pyrazolin-3-ylidene)cyclohexa-2,4-dien-1-one
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| Activity |
IC50 ~ 50000 nM
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[5] | |||
| Compound Name |
3-Butyl-6-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3908688
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
2-(2,3-Dichlorophenyl)-5-(methylamino)-1,3-oxazole-4-carbonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3262908; SCHEMBL16516282; BDBM50011735; NCGC00262519-01
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| Activity |
IC50 ~ 50000 nM
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[4] | |||
| Compound Name |
[3-(2-Hydroxy-5-methylphenyl)-1H-pyrazol-4-yl](4-methoxyphenyl)methanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1736078; MLS001163892; HMS2871C21; ZINC510454; BDBM50148021; STL036489; AKOS005647370; MCULE-4086867068; SMR000539275; AB00116185-01
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| Activity |
IC50 ~ 50000 nM
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[5] | |||
| Compound Name |
4-Chloro-2-[5-(2-chloro-phenyl)-1H-pyrazol-3-yl]-phenol
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1442717; SMR000123023; MLS000035498; HMS2409D21; BDBM50147986; ZINC13130770; AKOS000603367; MCULE-7617462188; ST074956; SR-01000524606; 4-chloro-2-[5-(2-chlorophenyl)pyrazol-3-yl]phenol; SR-01000524606-1
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| Activity |
IC50 ~ 50000 nM
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[5] | |||
| Compound Name |
2-Amino-N-butyl-5-propylthiophene-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3960955
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| Activity |
IC50 ~ 50000 nM
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[6] | |||
| Compound Name |
3,5-Diphenyl-1H-pyrazole
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Investigative | Compound Info | ||
| Synonyms |
3,5-Diphenylpyrazole; 1H-Pyrazole, 3,5-diphenyl-; Pyrazole, 3,5-diphenyl-; MFCD00039675; CHEMBL375966; 3,5-Diphenylpyrazole, 99%; EINECS 214-543-8; NSC126937; NSC 126937; Pyrazole,5-diphenyl-; ACMC-1BUFO; 1H-Pyrazole,5-diphenyl-; CBMicro_048085; 3,5-diphenyl-1H-pyrazol; 1H-Pyrazole,3,5-diphenyl-; MLS001194968; 3,5-Diphenylpyrazole, 97%; SCHEMBL1230353; DTXSID2061565; CTK4A8767; KS-00000DRJ; ZINC41746; HMS2868C24; ACT07883; BDBM50148009; STK328161; AKOS000421424; AKOS025394163; CCG-103967; CS-W007280; MCULE-1758921597; NSC-126937; NCGC00245818-01; AK142157; AS-16147; SMR000554573; SY033591; BIM-0047997.P001; DB-041220; D4197; FT-0606712; ST50331236; K-1048; AC-907/25014327; SR-01000390754; J-511375; SR-01000390754-1; Q22714645; F1011-0263; 3-AMINO-3-(2-HYDROXY-5-NITRO-PHENYL)-PROPIONICACID
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| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
3-Chloro-4-ethoxy-N-(2-(pyrrolidin-1-yl)phenyl)benzamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL370583; 3-chloro-4-ethoxy-N-[2-(pyrrolidin-1-yl)phenyl]benzamide; Oprea1_097634; SCHEMBL14825204; ZINC464460; BDBM50182504; STK355741; AKOS000464957; MCULE-7702536148; ST51028442; (3-chloro-4-ethoxyphenyl)-N-(2-pyrrolidinylphenyl)carboxamide
Click to Show/Hide
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| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
2-Cyclopentyl-5-(methylamino)-1,3-oxazole-4-carbonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3262918; BDBM50011746; NCGC00183425-01
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| Activity |
IC50 ~ 50000 nM
|
[4] | |||
| Compound Name |
5-Methyl-2-(5-p-tolyl-1H-pyrazol-3-yl)-phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1328952; CBMicro_011220; MLS001209799; SCHEMBL10358565; SCHEMBL16217095; HMS2821E17; SMSF0005870; BDBM50148011; ZINC13122806; AKOS000603257; CB14332; MCULE-2110291085; SMR000516050; BIM-0011284.P001; ST50007160; 5-methyl-2-[5-(4-methylphenyl)pyrazol-3-yl]phenol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-Amino-N,N-dibutyl-5-phenylthiophene-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3906604
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
Ethyl 2-(4-phenylbutanoylamino)benzoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL201191; ethyl 2-(4-phenylbutanamido)benzoate; ZINC363478; BDBM50182508; AKOS003305718; MCULE-6788538258; ST50721901; AB00121620-01
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
Mischellamine B
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL397803; BDBM50221403
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
4-Bromo-2-(3-phenyl-1H-pyrazol-5-yl)phenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1344000; MLS000547918; SCHEMBL1528282; HMS2350E15; BDBM50147966; ZINC13126471; (6Z)-4-bromo-6-(5-phenyl-1,2-dihydropyrazol-3-ylidene)cyclohexa-2,4-dien-1-one; SMR000113646; AN-829/36496003
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[5] | |||
| Compound Name |
2-Amino-N-butyl-5-methylthiophene-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3934572
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
2-(Benzylthio)-N-(3-chloro-2-methylphenyl)acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL202034; ZINC454526; BDBM50182497; STK267357; AKOS001279441; MCULE-3022018855; ST51079632; AB00108839-01; 2-(benzylsulfanyl)-N-(3-chloro-2-methylphenyl)acetamide; N-(3-chloro-2-methylphenyl)-2-(phenylmethylthio)acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[10] | |||
| Compound Name |
2-Amino-5-benzyl-N-butylthiophene-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3916837
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 50000 nM
|
[6] | |||
| Compound Name |
4-Bromophenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
p-Bromophenol; Phenol, 4-bromo-; p-Bromohydroxybenzene; 4-Bromo-phenol; p-Bromophenic acid; Phenol, p-bromo-; para-bromophenol; 4-bromo phenol; UNII-LAO4J0183I; MFCD00002313; CHEMBL57284; LAO4J0183I; 4-Bromophenol, 97%; 4-bromphenol; CCRIS 632; NSC 4970; EINECS 203-394-4; parabromophenol; parabromphenol; 4bromophenol; para bromophenol; AI3-14903; p-bromo phenol; p-bromo-phenol; p-bromophenol;; 4-bromopbenol; bromophenol-4; 4-bromanylphenol; HSDB 7650; 1,4-bromophenol; 4-bromohydroxybenzene; [O]c1ccc(Br)cc1; PubChem19708; 4-Bromophenol, 99%; ACMC-2098jl; SCHEMBL17443; KSC174Q1T; BIDD:ER0009; DTXSID3051543; CTK0H4819; NSC4970; 4-Bromophenol, analytical standard; ZINC404316; BCP17755; EBD44644; KS-000002LO; NSC-4970; STR02366; ANW-15343; BDBM50150779; SBB040917; STL281864; AKOS000118965; LS11445; MCULE-4578744293; PS-3353; BR-77152; SC-17542; DB-023687; 4-Bromophenol, purum, >=98.0% (HPLC); AM20050178; B0787; B3910; FT-0612047; ST50214520; 06B412; C14453; K-0536; 88240-EP2272817A1; 88240-EP2284148A1; 88240-EP2289868A1; 88240-EP2298731A1; 88240-EP2305648A1; A801434; J-001587; J-514834; Q26421193; Z57127362; F0001-0119
Click to Show/Hide
|
||||
| Activity |
IC50 = 55000 nM
|
[3] | |||
| Compound Name |
2-[[5-[5-[3-(1-Adamantyl)-4-methoxyphenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydroindol-1-yl]methyl]-2-aminopropane-1,3-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
SCHEMBL565374; CHEMBL3982447; BDBM60834; US9181182, 30
Click to Show/Hide
|
||||
| Activity |
EC50 ~ 55400 nM
|
[11] | |||
| Compound Name |
Chembl4164608
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277520
Click to Show/Hide
|
||||
| Activity |
IC50 = 58200 nM
|
[12] | |||
| Compound Name |
Hyrtenone A
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL465615; CTK0H8325; DTXSID60348415; BDBM50269747
Click to Show/Hide
|
||||
| Activity |
IC50 = 59000 nM
|
[13] | |||
| Compound Name |
Chembl4169621
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277546
Click to Show/Hide
|
||||
| Activity |
IC50 = 67900 nM
|
[12] | |||
| Compound Name |
N-(1H-Benzimidazol-2-yl)-4-[(2-hydroxy-3-methoxyphenyl)methylamino]benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3113167; SCHEMBL16646064; BDBM50447177; NCGC00319012-01; N-(1H-Benzoimidazole-2-yl)-4-(2-hydroxy-3-methoxybenzylamino)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 70000 nM
|
[7] | |||
| Compound Name |
4-Fluorobenzoic acid [4-[[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]methyl]phenyl]methyl ester
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1271221; MLS002607753; SCHEMBL1531915; BDBM50417166; NCGC00185038-01; SMR001522627; Q27164213
Click to Show/Hide
|
||||
| Activity |
Ki ~ 70000 nM
|
[14] | |||
| Compound Name |
3-Hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Flavonol; 3-Hydroxy-2-phenyl-4H-chromen-4-one; Flavon-3-ol; 3-Hydroxy-2-phenylchromone; 4H-1-Benzopyran-4-one, 3-hydroxy-2-phenyl-; FLAVONE, 3-HYDROXY-; 3-hydroxy-2-phenylchromen-4-one; UNII-ZTG9LSS5QH; MFCD00006832; ZTG9LSS5QH; NSC57653; CHEMBL294009; 3-hydroxy-2-phenyl-4H-1-benzopyran-4-one; NSC-57653; F0013-0884; flavonols; FLAVONE,3-HYDROXY-; NSC58585; SR-01000401360; EINECS 209-416-9; NSC 57653; NSC 58585; 3-hydroxyflavon; HSDB 7572; 3-hydroxy-2-phenyl-chromen-4-one; Spectrum_000328; SpecPlus_000831; Spectrum2_001392; Spectrum3_001432; Spectrum4_001845; Spectrum5_000350; ACMC-209m0e; Oprea1_038914; Oprea1_692205; SCHEMBL20246; 3-Hydroxyflavone, >=98%; 4-Hydroxy-3-oxylatoflavylium; BSPBio_003164; KBioGR_002250; KBioSS_000808; MLS002207277; BIDD:ER0553; DivK1c_006927; SPECTRUM1501012; SPBio_001404; MEGxp0_001695; DTXSID4060365; ACon1_000167; CTK3J2720; KBio1_001871; KBio2_000808; KBio2_003376; KBio2_005944; KBio3_002384; ZINC57675; HMS3740M15; KUC106685N; KS-00000VN5; WLN: T66 BO EVJ CR& DQ; ANW-32796; BDBM50187668; CCG-38858; NCI-57653; s4790; SBB000767; AKOS000599906; MCULE-8535739842; SDCCGMLS-0066736.P001; NCGC00095653-01; NCGC00095653-02; NCGC00095653-03; 3-Hydroxy-2-phenyl-4H-chromen-4-one #; AK163706; AS-19638; SMR000112317; ST086622; SY048803; KSC-11-207-16; DB-053103; HY-107825; CS-0030701; EU-0001678; FT-0615841; Y2009; VU0053575-3; C01495; H-5000; 3-Hydroxy-2-phenyl-4H-1-benzopyran-4-one, 9CI; Q5919049; SR-01000401360-1; SR-01000401360-2; BRD-K55150756-001-05-7; B48D3495-6D21-4742-8A87-D3DE07DC9554
Click to Show/Hide
|
||||
| Activity |
IC50 = 73000 nM
|
[2] | |||
| Compound Name |
Chembl4160880
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277518
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
Geranyloxy-coumarin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2086412; BDBM50391169; 3-[(2E)-3,7-dimethylocta-2,6-dienoxy]chromen-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[8] | |||
| Compound Name |
5-[(2-Methoxybenzyl)oxy]-7-methyl-4-phenyl-2H-chromen-2-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL202482; 5-((2-methoxybenzyl)oxy)-7-methyl-4-phenyl-2H-chromen-2-one; Oprea1_643728; Oprea1_819431; ZINC1155627; BDBM50182515; STL458475; AKOS016365000; MCULE-8213212498; 5-(2-methoxybenzyloxy)-7-methyl-4-phenyl-2H-chromen-2-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
6,7-Methylenedioxy-2-t-butylbenzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL238812; BDBM50222289
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
7-Hydroxy-2-isobutyl-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL396673; BDBM50222313
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
2-Isobutyl-3-hydroxy-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL239022; BDBM50222274
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Chembl4169224
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS003826356; BDBM50277501; SMR002504557; 2-amino-5-benzoyl-4-(2,4-dichlorophenyl)-1H-pyrrole-3-carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
3-(3,4-Dimethoxyphenyl)-3,4-dihydro-2H-chromene-7,8-diol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL239053; NSC603663; HIR-11; SCHEMBL10563966; BDBM153381; BDBM50222304; NSC-603663; 7,8-dihydroxy-3'',4''-dimethoxyisoflavan; 3-(3,4-Dimethoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7,8-diol
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
2,6-Dibromophenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Phenol, 2,6-dibromo-; 2,6-Dibromo-phenol; UNII-27MIP05EAV; MFCD00002152; 2,6-dibromo-pheno; 2,6-Bis(Bromanyl)phenol; 27MIP05EAV; CHEMBL111507; HSDB 7652; NSC 6214; EINECS 210-161-0; ACMC-1AU9I; 2,6-Dibromophenol, 99%; KSC493E5T; SCHEMBL416446; DTXSID0060561; CTK3J3259; KS-00000JJJ; NSC6214; ZINC334875; ACT11780; EBD22566; HY-Y1667; NSC-6214; ANW-33596; BDBM50150789; RW1225; SBB101028; AKOS009152462; 2,6-Dibromophenol, analytical standard; AS06977; CS-W009153; LS11453; MCULE-3282492293; AC-23653; AK-30552; AS-14432; BR-30552; SC-13249; SY014521; DB-005881; AM20060859; D3384; FT-0610560; ST50826657; EN300-29657; A19919; C16247; M-5637; 608D333; AJ-087/41885654; Q209273; W-105226; Z1250100725
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-(3-Isopropylphenyl)-4-(2-hydroxy-3-methoxybenzylamino)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3113197; SCHEMBL16646024; BDBM50447181; 4-[(2-hydroxy-3-methoxyphenyl)methylamino]-N-(3-propan-2-ylphenyl)benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
(5-Amino-4-(3,4-dichlorobenzoyl)-3-(2,6-difluorophenyl)-1H-pyrrol-2-yl)(phenyl)methanone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2141695; MLS003648354; BDBM50277484; SMR002338528
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
Pyridine-2,6-dicarboxylic acid bis-(phenethyl-amide)
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL383793; SMR000513481; Oprea1_075523; Oprea1_153653; MLS001075798; MLS001207478; HMS2194F18; HMS3336C09; ZINC816644; BDBM50182512; STK371281; AKOS000577293; MCULE-4741646226; N,N'-Diphenethyl-2,6-pyridinedicarboxamide; N2,N6-diphenethylpyridine-2,6-dicarboxamide; ST50923076; N~2~,N~6~-diphenethyl-2,6-pyridinedicarboxamide; SR-01000408184; N,N'-bis(2-phenylethyl)-2,6-pyridinedicarboxamide; N,N'-bis(2-phenylethyl)pyridine-2,6-dicarboxamide; SR-01000408184-1; N-(2-phenylethyl){6-[N-(2-phenylethyl)carbamoyl](2-pyridyl)}carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
N-(2-Benzoxazolyl)-4-(2-hydroxy-3-methoxybenzylamino)benzenesulfonamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3113166; SCHEMBL16646088; BDBM50447176; NCGC00345009-01; N-(1,3-benzoxazol-2-yl)-4-[(2-hydroxy-3-methoxyphenyl)methylamino]benzenesulfonamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[7] | |||
| Compound Name |
Chembl4177482
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277514
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
7-Hydroxy-2-propylchromen-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL241363; 7-hydroxy-2-propyl-4H-chromen-4-one; Maybridge1_002254; 4H-1-Benzopyran-4-one, 7-hydroxy-2-propyl-; Oprea1_100104; HMS547O10; ZINC133002; BDBM50222311; BTB 10040; CCG-46184; MFCD00100589; MCULE-5977339715; 7-hydroxy-2-propyl-4H-benzopyran-4-one; SR-01000635896-1
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Chembl4164711
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS004551690; BDBM50277523; SMR003334305; (5-amino-3-(2,4-dichlorophenyl)-4-(thiophene-2-carbonyl)-1H-pyrrol-2-yl)(phenyl)methanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
7-Hydroxy-2-pentyl-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL241366; SCHEMBL3658287; 7-hydroxy-2-pentylchromen-4-one; BDBM50222286
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
4-Bromophenetole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
p-Bromophenetole; 1-Bromo-4-ethoxybenzene; Benzene, 1-bromo-4-ethoxy-; 4-Bromophenyl ethyl ether; 4-bromoethoxybenzene; p-Bromoethoxybenzene; p-Ethoxybromobenzene; 1-Bromo-4-ethoxy-benzene; p-Ethoxyphenyl bromide; p-Bromophenol ethyl ether; Phenetole, p-bromo-; UNII-T0L17BX1WR; 4-bromo phenetole; MFCD00000098; 4-ethoxybromobenzene; 1-BROMO-4-ETHYLOXYBENZENE; NSC 8053; T0L17BX1WR; CHEMBL187292; OTAVA-BB 1786453; p-bromophenetol; 4-bromophenetol; phenetyl bromide; 4-bromo phenetol; NSC8053; EINECS 209-629-7; 4-ethoxybromo-benzene; PubChem3138; 1-ethoxy-4-bromobenzene; p-bromophenyl ethyl ether; 4-Bromophenetole, 97%; 4-Bromophenetole, 98%; ethyl 4-bromophenyl ether; 4-Bromophenetole (4BP); ACMC-209m7v; 2-METHYLGLUTARICACID; SCHEMBL18358; KSC271S0F; Phenetole, p-bromo- (8CI); 4-ETHOXY BROMO BENZENE; DTXSID6060426; CTK1H1902; ZINC407014; ACT08100; KS-00000D7H; NSC-8053; ANW-33065; BDBM50150786; SBB059353; AKOS000119004; AS03448; MCULE-7760251246; VZ28620; AK-47317; BC002408; BR-47317; DS-14348; SC-05560; SY001830; DB-028768; AM20060683; ST50406518; M-5946; W-105361; Q27289511; F0001-1538
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
7-Hydroxy-2-t-butyl-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL241365; 2-t-butyl-7-hydroxychromone; SCHEMBL8493156; BDBM50222302
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
6-Hydroxy-2-isobutyl-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL395115; BDBM50222312; ZINC28875393
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
3-Hydroxy-2-pentyl-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL241794; SCHEMBL957193; BDBM50222288
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
2-Ethyl-3-hydroxy-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL238815; BDBM50222298; 2-ethyl-3-hydroxy-4 H-benzopyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Chembl4162293
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277547
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
Chembl4172644
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277500
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
N-[(5-Bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1573436; SMR001355490; MLS002729016; MLS003370621; SCHEMBL2598269; ML127; BDBM50350396; NCGC00183685-01; NCGC00183685-02; NCGC00183685-04; NCGC00188369-01; NCGC00188369-02; NCGC00188369-03; NCGC00188370-01; NCGC00188370-02; NCGC00188370-03; Q27163564; N-[(5-bromo-8-hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[9] | |||
| Compound Name |
2-Isobutyl-6,7-methylenedioxybenzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL238813; BDBM50222292
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
6,7-Dihydroxy-4''-nitroisoflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL238821; BDBM50222279
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Chembl4162344
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277496
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
13-Keto-9Z,11E-octadecadienoic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(9Z,11E)-13-Oxooctadeca-9,11-dienoic acid; 13-OXO-ODE; 13-oxo-9Z,11E-ODE; 13-OxoODE; 13-KODE; 13-ketooctadecadienoic acid; CHEMBL1378466; 13-ketoODE; 13-Oxo-9Z,11E-octadecadienoic acid; (9Z,11E)-13-Oxooctadeca-9,11-dienoate; (E,Z)-13-Oxo-9,11-octadecadienoic acid; 9,11-Octadecadienoic acid, 13-oxo-, (E,Z)-; 13-Ketooctadecadienoioc acid; BSPBio_001333; BML1-E02; SCHEMBL2513742; HMS1791C15; HMS1989C15; HMS3402C15; ZINC4655398; 13-ketooctadeca-9,11-dienoic acid; Eicosanoids_13-oxoODE_C18H30O3; BDBM50045522; LMFA02000016; 13-Keto-octadeca-9Z,11E-dienoic acid; NCGC00161271-01; NCGC00161271-02; NCGC00161271-03; C14765; (9z,11e)-13-oxo-octadeca-9,11-dienoic acid; 9,11-Octadecadienoic acid, 13-oxo-, (9Z,11E)-; Q27104960
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[15] | |||
| Compound Name |
6-Hydroxydihydrodaidzein
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6,7,4'-Trihydroxyisoflavanone; 4',6,7-trihydroxyisoflavanone; CHEMBL239032; 6,7-dihydroxy-3-(4-hydroxyphenyl)-2,3-dihydro-4h-chromen-4-one; SCHEMBL572236; 4'',6,7-trihydroxyisoflavanone; CTK8D4805; DTXSID60916491; 6,7-dihydroxy-3-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one; BDBM50222296; 4H-1-Benzopyran-4-one, 2,3-dihydro-6,7-dihydroxy-3-(4-hydroxyphenyl)-; 6,7-Dihydroxy-3-(4-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one; 6,7-dihydroxy-3-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Chembl4165793
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277502
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
3-Hydroxy-2-propyl-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL394258; BDBM50222281
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
6-Hydroxy-2-isopropyl-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL240713; BDBM50222314
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
4H-1-Benzopyran-4-one, 2-(1,1-dimethylethyl)-6-hydroxy-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL147999; ACMC-20n61s; SCHEMBL7574697; CTK0B1618; DTXSID60449673; BDBM50222280; ZINC12353725; 2-tert-Butyl-6-hydroxy-chromen-4-one; 6-hydroxy-2-t-butyl-4H-benzopyran-4-one; 2-TERT-BUTYL-6-HYDROXYCHROMEN-4-ONE
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
2-[4-[(4-Fluorophenyl)methoxy]but-2-ynylsulfanyl]-5-naphthalen-1-yl-1,3,4-oxadiazole
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1271324; BDBM50417169
Click to Show/Hide
|
||||
| Activity |
Ki ~ 100000 nM
|
[14] | |||
| Compound Name |
Chembl4176066
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS003648352; BDBM50277498; SMR002338526; (5-amino-4-(4-chlorobenzoyl)-3-(2,4-dichlorophenyl)-1H-pyrrol-2-yl)(phenyl)methanone
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
2-(3-Chlorophenoxy)-N-(4-methylbenzyl)propanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL201368; 2-(3-chlorophenoxy)-N-[(4-methylphenyl)methyl]propanamide; BDBM50182503; STK134096; AKOS003297436; AKOS017065277; MCULE-3427061928; ST50943912; 2-(3-Chloro-phenoxy)-N-(4-methyl-benzyl)-propionamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
2-Ethyl-6-hydroxy-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL394459; BDBM50222299
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
2-Phenoxy-N-{[4-(pyridin-4-ylmethyl)phenyl]carbamothioyl}acetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL201812; Oprea1_585139; ZINC1183098; BDBM50182498; STK003450; AKOS003224499; MCULE-4992459652; AB00112239-01; 1-(2-phenoxyacetyl)-3-(4-(pyridin-4-ylmethyl)phenyl)thiourea
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
Ethyl 1H-pyrrole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Ethyl pyrrole-2-carboxylate; Ethyl 2-pyrrolecarboxylate; Ethyl pyrrole-2-carbonate; 1H-Pyrrole-2-carboxylic acid, ethyl ester; ethylpyrrole-2-carboxylate; MFCD00817049; CHEMBL4175237; PYRROLE-2-CARBOXYLIC ACID ETHYL ESTER; Pyrrole-2-carboxylic acid, ethyl ester; 1H-pyrrole-2-carboxylic acid ethyl ester; Ethyl1H-pyrrole-2-carboxylate; 2-(Ethoxycarbonyl)-1H-pyrrole; ethoxycarbonylpyrrole; PubChem14843; ACMC-209fqc; 2-ethoxycarbonyl-pyrrole; ethyl pyrrole carboxylate; ethyl pyrrole 2-carboxylate; ethyl-pyrrole-2-carboxylate; NCIOpen2_000674; KSC493K5D; SCHEMBL428389; ethyl-1H-pyrrole-2-carboxylate; CTK3J3551; DTXSID90292290; 1-ethyl-1H-pyrrole-2-carboxylate; ZINC165736; Ethyl 1H-pyrrole-2-carboxylate #; ACN-S004188; ACT01682; KS-000004YY; NSC81360; ANW-24658; BBL101270; BDBM50277521; NSC-81360; SBB053894; STL555066; WT1336; AKOS005070312; AC-1481; CS-W001038; LS20212; MCULE-8658466323; VP60100; AK-25609; BR-25609; SC-16322; SY006751; 2199-43-1 ethyl pyrrole-2-carboxylate; AB0002194; DB-007509; A4718; AM20090208; C2762; E1030; Ethyl 1H-pyrrole-2-carboxylate, AldrichCPR; FT-0600691; A-2203; 199E431; 3X-0740; W-206701; Z292815334
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
Ethyl 5-Amino-1H-pyrrole-2-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
Ethyl 5-Aminopyrrole-2-carboxylate; CHEMBL4168041; MFCD11656573; 1H-Pyrrole-2-carboxylic acid, 5-amino-, ethyl ester; 1H-Pyrrole-2-carboxylicacid,5-amino-,ethylester; SCHEMBL2361219; CTK8B5100; KS-00003KRN; DTXSID00476847; ANW-47568; BDBM50277522; ZINC45792907; AKOS015919568; FS-2666; BR-31186; SY035524; AB0026582; W8281; S-5436
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
6-Hydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6-hydroxy-2-phenylchromen-4-one; 6-Hydroxy-2-phenyl-4-benzopyrone; 6-Monohydroxyflavone; 6-Hydroxy-2-phenyl-4H-chromen-4-one; 6-Hydroxy-2-phenyl-chromen-4-one; MLS000738065; UNII-148S6Z78H6; 6-Hydroxyflavone, 98%; MFCD00017329; NSC-26744; CHEMBL138649; 4H-1-Benzopyran-4-one, 6-hydroxy-2-phenyl-; NSC26744; 148S6Z78H6; EINECS 229-704-8; NSC 26744; 6-Hydroxyflavone (6-HF); Diisononyladipate; 6-hydroxy-flavone; 6-Hydroxy flavone; 6-Hydroxyflavone, 10; ACMC-1B9IO; BIDD:ER0190; SCHEMBL676594; MEGxp0_001697; DTXSID8022327; ACon1_002026; ZINC57677; HMS2764K07; HMS3885I17; ACT08319; HY-N7110; ANW-75600; BDBM50081950; s3634; SBB000766; AKOS002670169; CCG-214625; MCULE-9337240832; NCGC00179903-01; NCGC00179903-03; 6-Hydroxy-2-phenyl-4H-chromen-4-one #; AS-57550; SC-08572; SMR000393737; 6-hydroxy-2-phenyl-4-oxo-4H-1-benzopyran; DB-054947; CS-0030698; FT-0621167; ST50307711; 4H-1-Benzopyran-4-one,6-hydroxy-2-phenyl-; C14137; Q2817908; BRD-K04253610-001-01-6
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Chembl4172607
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
MLS003826299; BDBM50277483; SMR002504523; (5-amino-3-(2,4-dichlorophenyl)-1H-pyrrole-2,4-diyl)bis(phenylmethanone)
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
Texasin
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
6,7-Dihydroxy-4'-methoxyisoflavone; 6,7-Dihydroxy-3-(4-methoxyphenyl)-4-benzopyrone; FORMONETIN; CHEMBL239028; 6,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one; EINECS 212-980-9; TEXASIN(RG); C10536; 6,7-dihydroxy-3-(4-methoxyphenyl)chromen-4-one; SCHEMBL4728656; DTXSID10237860; ZINC6484559; BDBM50222287; LMPK12050101; 6,7-dihydroxy-4''-methoxyisoflavone; AC-31488; FT-0764584; Q27108415
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
6,7-Dihydroxy-3-(1,3-benzodioxol-5-yl)-4H-1-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL239030; SCHEMBL10562034; BDBM50222294; 6,7-dihydroxy-3'',4''-methylenedioxyisoflavone; 3-(1,3-benzodioxol-5-yl)-6,7-dihydroxychromen-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
3-Bromophenol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
m-Bromophenol; Phenol, 3-bromo-; 3-bromo phenol; 3-Bromo-phenol; Phenol, m-bromo-; UNII-VMU0X6956Y; MFCD00002253; 3-Bromophenol, 98%; CHEMBL185651; VMU0X6956Y; OTAVA-BB 1287431; meta bromophenol; meta-bromophenol; 3 bromophenol; 3-bromanylphenol; HSDB 7649; meta-bromo-phenol; EINECS 209-706-5; 3-bromophenyl alcohol; PubChem3824; ACMC-1CUCG; 3-BROM-PHENOL; 1-bromo-3-hydroxy-benzene; CHEMWISH IC03776; SCHEMBL49927; KSC269I4J; DTXSID9060449; ARKPHARMLTD ARK-02495; CTK1G9444; 3-BROMO-1-HYDROXYBENZENE; ZINC388034; ACT00927; KS-000002OV; STR02996; ANW-33162; BDBM50150795; STL280238; AKOS000118744; AS00214; MCULE-7883689277; PS-4040; BC002623; BR-44013; SC-05579; DB-006384; 3-Bromophenol, purum, >=97.5% (HPLC); AM20060304; B0629; FT-0601041; FT-0615113; ST50826980; 91B208; M-5873; A832171; Q-200364; Q26421128; F0001-1548; Z1262252924
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-(5-Butyramido-2-chlorophenyl)benzofuran-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL370234; Oprea1_155280; ZINC798601; BDBM50182502; AKOS000603099; MCULE-1459716428; ST50023358; N-[3-(benzo[d]furan-2-ylcarbonylamino)-4-chlorophenyl]butanamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
1,6-Bis[4-(2-methoxyphenyl)piperazin-1-yl]hexane-1,6-dione
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL202698; 1,6-bis(4-(2-methoxyphenyl)piperazin-1-yl)hexane-1,6-dione; BDBM50182511; STK441584; ZINC13681960; AKOS003307903; MCULE-1579990351; ST50922757; 1,6-bis[4-(2-methoxyphenyl)piperazinyl]hexane-1,6-dione
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
N-(5-Chloro-2-methoxyphenyl)-3-methyl-1-benzofuran-2-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL383552; Cambridge id 6671738; ZINC136457; BDBM50182506; STK702551; AKOS000663286; MCULE-6598711495; ST029413; AB00115329-01; Z28182807; N-(5-chloro-2-methoxyphenyl)-3-methylbenzofuran-2-carboxamide; N-(5-chloro-2-methoxyphenyl)(3-methylbenzo[d]furan-2-yl)carboxamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
7-Hydroxy-2-isopropyl-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL241364; 7-hydroxy-2-isopropylchromone; SCHEMBL14243496; BDBM50222310
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
6,7-Methylenedioxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL238814; BDBM50222305; 6,7-methylenedioxy-2-phenylbenzopyran-4-one; 6-phenyl-[1,3]dioxolo[4,5-g]chromen-8-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Ethyl 1-(3-(3,5-dimethylphenylamino)-3-oxopropyl)piperidine-4-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL204926; Oprea1_515664; Oprea1_601346; MLS000689098; HMS2708O21; ZINC4725186; BDBM50182513; STK232605; AKOS000551083; MCULE-4345541428; SMR000283136; ST50015926; SR-01000481777; SR-01000481777-1; BRD-K62871870-001-07-6; ethyl 1-{2-[N-(3,5-dimethylphenyl)carbamoyl]ethyl}piperidine-4-carboxylate; ethyl 1-{3-[(3,5-dimethylphenyl)amino]-3-oxopropyl}piperidine-4-carboxylate
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
N-Benzyl-3-((2,3-dihydro-1H-inden-5-yloxy)methyl)benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL202366; N-benzyl-3-[(2,3-dihydro-1H-inden-5-yloxy)methyl]benzamide; MLS000579321; HMS2554O08; ZINC2836241; BDBM50182499; SMR000198603
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
2-([1,2,4]Triazolo[4,3-a]quinolin-1-ylthio)-N-phenethylacetamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL204917; ZINC1128596; BDBM50182505; AKOS000812429; MCULE-2488923601; VU0618158-1; F3394-0504; Z275024050; N-(2-phenylethyl)-2-([1,2,4]triazolo[4,3-a]quinolin-1-ylthio)acetamide; N-(2-phenylethyl)-2-{[1,2,4]triazolo[4,3-a]quinolin-1-ylsulfanyl}acetamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
4H-1-Benzopyran-4-one, 6-hydroxy-2-propyl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL240505; 6-hydroxy-2-propyl-4h-chromen-4-one; SCHEMBL7573134; CTK2D7764; DTXSID80453015; BDBM50222283; 6-HYDROXY-2-PROPYLCHROMEN-4-ONE; 6-hydroxy-2-propyl-4H-benzopyran-4-one
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
Chembl4168816
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277519
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
Chembl4173713
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277515
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
3,6-Dihydroxyflavone
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
3,6-dihydroxy-2-phenyl-4H-chromen-4-one; 3,6-dihydroxy-2-phenylchromen-4-one; 6-Hydroxyflavonol; 3,6-dihydroxy-flavone; 4H-1-Benzopyran-4-one, 3,6-dihydroxy-2-phenyl-; CHEMBL210411; MFCD00143082; ACMC-1C7FZ; Oprea1_396152; SCHEMBL1627936; 3,6-Dihydroxy-2-phenylchromone; CTK4A5918; ZINC57648; DTXSID90350940; BDBM50187657; STL512574; AKOS024307412; MCULE-8833300798; AS-64082; D5191; FT-0734795; ST50319482; Y1999; J-002077
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
3-Hydroxy-2-t-butyl-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL239023; BDBM50222282
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
2-Chloro-N-{2-methyl-4-[(phenylsulfanyl)methyl]phenyl}benzamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL202533; ZINC2085192; BDBM50182507; STL120986; AKOS003248622; MCULE-5923565433; AB00117838-01; AH-487/40936377; 2-chloro-N-(2-methyl-4-(phenylthiomethyl)phenyl)benzamide
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[10] | |||
| Compound Name |
Chembl4170264
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277473
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
4-Bromobenzyl alcohol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
(4-Bromophenyl)methanol; p-Bromobenzyl alcohol; Para-Bromobenzyl Alcohol; 4-bromobenzylalcohol; Benzenemethanol, 4-bromo-; MFCD00004650; (4-bromophenyl)-methanol; Benzyl alcohol, p-bromo-; (4-Bromo-phenyl)-methanol; (4-bromophenyl)methan-1-ol; 4-Bromobenzyl alcohol, 99%; CHEMBL184410; 4-HYDROXYMETHYL-1-BROMOBENZENE; p-Bromo-benzyl alcohol; CCRIS 5119; EINECS 212-851-7; 4-Bromophenylmethanol; 4-bromo-benzylalcohol; 4-bromobenzyl-alcohol; PubChem3748; ACMC-1BL3V; (4-Bromophenyl)methanol #; ASISCHEM V60455; KSC492I8P; SCHEMBL104349; RARECHEM AL BD 0075; CTK3J2487; VEDDBHYQWFOITD-UHFFFAOYSA-; DTXSID50236276; OTAVA-BB 1782769; ZINC404753; ACT13272; EBD35045; KS-000002MU; ANW-38685; BDBM50150787; SBB064717; AKOS000249367; AS03954; CS-W004067; DB02822; MCULE-6643975109; PS-5313; (4-Bromophenyl)methanol;Brombenzylalcohol; AC-17025; AC-26171; AK-93775; BC002554; SC-07090; SY006440; AB0019780; DB-017995; AM20050135; FT-0617870; FT-0617871; ST50406657; V0282; A22470; B-3820; W-104028; Q27093776; Z1741959491
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
Chembl4177082
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
BDBM50277495
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[12] | |||
| Compound Name |
2-Isopropyl-3-hydroxy-4H-benzopyran-4-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL238816; BDBM50222275
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
{2,6-Di-tert-butyl-4-[1-(3,5-di-tert-butyl-4-carboxymethoxyphenylsulfanyl)-1-methylethylsulfanyl]phenoxy}-acetic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL104500; BDBM50156940
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 125000 nM
|
[16] | |||
| Compound Name |
15-Oxo-puupehenoic Acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1165243; BDBM50320453
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 150000 nM
|
[17] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 4 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
BW755C
Click to Show/Hide
|
Terminated | Compound Info | ||
| Synonyms |
BW755C; 66000-40-6; BW-755C; UNII-6V6JF56BXO; 6V6JF56BXO; CHEMBL274642; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 1-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1H-pyrazol-3-amine; 1-(3-trifluoromethylphenyl)-4,5-dihydro-1H-pyrazol-3-amine; 1-(3-Trifluoromethyl-phenyl)-4,5-dihydro-1H-pyrazol-3-ylamine; 4,5-DIHYDRO-1-[3-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOL-3-AMINE; 1-(3-(trifluoromethyl)phenyl)-4,5-dihydro-1H-pyrazol-3-amine; BW 755C; EINECS 266-051-8; AC1L2IRR; SCHEMBL2573191; CTK5C3353; DTXSID30216213
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| Activity |
IC50 = 213000 nM
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[18] | |||
| Compound Name |
NEODYSIDENIN
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Investigative | Compound Info | ||
| Synonyms |
neodysidenin; CHEMBL392270
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| Activity |
Ki > 500000 nM
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[1] | |||
| Compound Name |
Halenaquinol sulfate
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Investigative | Compound Info | ||
| Synonyms |
Halenaquinol Sulfate Sodium; CHEMBL455880
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| Activity |
IC50 > 200000 nM
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[13] | |||
| Compound Name |
2-(4-Chloro-2-methylphenoxy)-N-[2-hydroxy-5-(propan-2-yl)phenyl]acetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL202560; Oprea1_667959; ZINC307976; BDBM50182500; STK184320; AKOS003255387; MCULE-8804263745; 2-(4-chloro-2-methylphenoxy)-N-(2-hydroxy-5-isopropylphenyl)acetamide
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| Activity |
IC50 > 200000 nM
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[10] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries. Bioorg Med Chem. 2007 Nov 15;15(22):6900-8. | ||||
| REF 2 | Structure-activity relationship studies of flavonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2. Bioorg Med Chem. 2007 Dec 1;15(23):7408-25. | ||||
| REF 3 | Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. J Med Chem. 2004 Jul 29;47(16):4060-5. | ||||
| REF 4 | Potent and selective inhibitors of human reticulocyte 12/15-lipoxygenase as anti-stroke therapies. J Med Chem. 2014 May 22;57(10):4035-48. | ||||
| REF 5 | A potent and selective inhibitor targeting human and murine 12/15-LOX. Bioorg Med Chem. 2016 Mar 15;24(6):1183-90. | ||||
| REF 6 | Design of a novel thiophene inhibitor of 15-lipoxygenase-1 with both anti-inflammatory and neuroprotective properties. Eur J Med Chem. 2016 Oct 21;122:786-801. | ||||
| REF 7 | Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase. J Med Chem. 2014 Jan 23;57(2):495-506. | ||||
| REF 8 | Synthesis and SAR studies of mono O-prenylated coumarins as potent 15-lipoxygenase inhibitors. Eur J Med Chem. 2012 Nov;57:134-42. | ||||
| REF 9 | Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase. J Med Chem. 2011 Aug 11;54(15):5485-97. | ||||
| REF 10 | Novel human lipoxygenase inhibitors discovered using virtual screening with homology models. J Med Chem. 2006 Feb 23;49(4):1356-63. | ||||
| REF 11 | US patent application no. 9181182B2, S1P receptors modulators | ||||
| REF 12 | Photoactivation provides a mechanistic explanation for pan-assay interference behaviour of 2-aminopyrroles in lipoxygenase inhibition. Eur J Med Chem. 2017 Oct 20;139:633-643. | ||||
| REF 13 | Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. J Nat Prod. 2003 Feb;66(2):230-5. | ||||
| REF 14 | Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1. J Med Chem. 2010 Oct 28;53(20):7392-404. | ||||
| REF 15 | Inhibitory and mechanistic investigations of oxo-lipids with human lipoxygenase isozymes. Bioorg Med Chem. 2014 Aug 1;22(15):4293-7. | ||||
| REF 16 | Discovery of novel phenolic antioxidants as inhibitors of vascular cell adhesion molecule-1 expression for use in chronic inflammatory diseases. J Med Chem. 2004 Dec 2;47(25):6420-32. | ||||
| REF 17 | Using enzyme assays to evaluate the structure and bioactivity of sponge-derived meroterpenes. J Nat Prod. 2009 Oct;72(10):1857-63. | ||||
| REF 18 | 1-Phenyl-[2H]-tetrahydropyridazin-3-one, A-53612, a selective orally active 5-lipoxygenase inhibitor. Bioorg Med Chem Lett. 1992 Nov;2(11):1353-6. | ||||
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