Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T15745 | Target Info | |||
| Target Name | Bromodomain adjacent to zinc finger 2B (BAZ2B) | ||||
| Synonyms |
hWALp4; KIAA1476; Bromodomain adjacent to zinc finger domain protein 2B
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| Target Type | Literature-reported Target | ||||
| Gene Name | BAZ2B | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 18 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
4-[3-[2-(4-Methyltriazol-1-yl)ethyl]imidazol-4-yl]benzonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415181; BDBM50078639
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
4-[3-Methyl-5-(1-methylpyrazol-4-yl)imidazol-4-yl]benzonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415183; BDBM50078637
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
4-[3-[2-(4-Methyltriazol-1-yl)ethyl]-5-pyridin-3-ylimidazol-4-yl]benzonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415178; BDBM50078630
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
4-[5-(3-Methyl-1,2-oxazol-5-yl)-3-[2-(4-methyltriazol-1-yl)ethyl]imidazol-4-yl]benzonitrile
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3415180; BDBM50078640
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| Activity |
IC50 ~ 50000 nM
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[1] | |||
| Compound Name |
N-Ethyl-2-acetyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110257; BDBM50495364
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| Activity |
IC50 = 50000 nM
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[2] | |||
| Compound Name |
2-Acetyl-N-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indole-8-sulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110258; BDBM50495375
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| Activity |
IC50 = 55000 nM
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[2] | |||
| Compound Name |
3-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)propanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110250; BDBM50495387
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| Activity |
IC50 = 66000 nM
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[2] | |||
| Compound Name |
2-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)-N-methylacetamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110253; BDBM50495376
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| Activity |
IC50 = 69000 nM
|
[2] | |||
| Compound Name |
N,2-Dimethyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL1513201; HMS1919G18; ZINC1431623; BDBM50495427; STK499824; AKOS000667010; MCULE-6004134216; NCGC00141995-01; N,2-Dimethyl-5-(3-methyl-1,2,4-triazolo[3,4-a]phthalazine-6-yl)benzenesulfonamide
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| Activity |
IC50 ~ 100000 nM
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[3] | |||
| Compound Name |
1-[1-(Imidazo[1,2-A]pyridin-5-Yl)-7-(Morpholin-4-Yl)indolizin-3-Yl]ethanone
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3740819; SCHEMBL21227718; Q27455831; Ethanone, 1-[1-imidazo[1,2-a]pyridin-5-yl-7-(4-morpholinyl)-3-indolizinyl]-
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| Activity |
IC50 ~ 100000 nM
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[4] | |||
| Compound Name |
N,N,2-Trimethyl-5-(3-methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3108781; ZINC1431624; BDBM50495429; STK796216; AKOS000667011; MCULE-3420882507; N,N,2-trimethyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide
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| Activity |
IC50 ~ 100000 nM
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[3] | |||
| Compound Name |
N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]methanesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110357; ZINC5303354; BDBM50495428; STK796556; AKOS005612901; MCULE-8228444058; N-[2-Methyl-5-(3-methyl-1,2,4-triazolo[3,4-a]phthalazine-6-yl)phenyl]methanesulfonamide
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| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]propanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3108806; ZINC5306176; BDBM50495432; STK592391; AKOS005514326; MCULE-7491487388
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| Activity |
IC50 ~ 100000 nM
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[3] | |||
| Compound Name |
2-Acetyl-8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-B]indole
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110261; C13H13FN2O; BDBM50495374; STK719137; ZINC12409967; AKOS005535100; AB26217; MCULE-9607737992; 8-Fluoro-2-acetyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole; 1-(8-fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)ethanone
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| Activity |
IC50 = 102000 nM
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[2] | |||
| Compound Name |
N-Methyl-6-phenylpyridine-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110244; SCHEMBL1542986; BDBM50495381; ZINC13466589; AKOS034141959
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| Activity |
IC50 = 109000 nM
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[2] | |||
| Compound Name |
3-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)-N-methylpropanamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110251; BDBM50495377
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| Activity |
IC50 = 143000 nM
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[2] | |||
| Compound Name |
2-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110252; BDBM50495382
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| Activity |
IC50 = 152000 nM
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[2] | |||
| Compound Name |
Pyrazine-2-carbothioamide
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Investigative | Compound Info | ||
| Synonyms |
Thiopyrazinamide; Pyrazinecarbothioamide; Pyrazine-2-thiocarboxamide; Pyrazinecarboxamide, thio-; 2-Pyrazinecarbothioamide; Pyrazinecarboxylic acid thioamide; UNII-JI046KHA6S; JI046KHA6S; CHEMBL2441350; NSC18377; MFCD00173663; 2-Pyrazinethiocarboxamide; NSC 18377; BRN 0002638; pyrazine carbothioamide; Pyrazinethiocarboxamide; Pyrazine thiocarboxamide; ACMC-20ajt5; WLN: T6N DNJ BYZUS; Pyrazinecarbothioamide (9CI); 5-25-04-00191 (Beilstein Handbook Reference); SCHEMBL1459989; CTK1D7043; DTXSID00196699; aminopyrazin-2-ylmethane-1-thione; Pyrazine-2-thiocarboxamide, 97%; ZINC165372; ALBB-014819; BDBM50495380; NSC-18377; SBB028262; STL301980; AKOS005174561; MCULE-7470857415; AS-19810; DB-026872; BB 0216583; FT-0635371; R2406; Y9158; EN300-51390; 604P722; J-524075; F2147-0547
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| Activity |
IC50 = 190000 nM
|
[2] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 9 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
N-Methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110245; DTXSID30640498; BDBM50495389; ZINC13466601; Q27453104; N-Methyl-2,3-dihydrothieno[3,4-b]-1,4-dioxin-5-carboxamide
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| Activity |
IC50 = 241000 nM
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[2] | |||
| Compound Name |
4,6-Dihydroxy-2-mercaptopyrimidine
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Investigative | Compound Info | ||
| Synonyms |
2-mercaptopyrimidine-4,6-diol; 2-Mercapto-pyrimidine-4,6-diol; 2-sulfanylpyrimidine-4,6-diol; CHEMBL1650611; 6-hydroxy-2-sulfanylidene-1H-pyrimidin-4-one; SCHEMBL97719; KSC677Q8D; 2-mercapto-4,6-pyrimidinediol; 2-Sulfanyl-4,6-pyrimidinediol; SCHEMBL11729920; SCHEMBL17382471; CTK0B0426; CTK5H7881; BCP12560; CS-M1811; ZINC5491117; 2-mercapto-4,6-dihydroxy-pyrimidine; 4,6-dihydroxy-2-mercapto-pyrimidine; 6484AC; ANW-30988; BDBM50298786; BDBM50495388; NSC266155; SBB004132; AKOS006229437; LS20487; NSC-266155; KS-000011O0; AC-10774; AC-28083; BR-46704; SC-25598; AB0066144; FT-0687943; ST50308261; Z2575; S-1631; 32363-EP2301933A1; 32363-EP2311827A1; 4,6-Dihydroxy-2-Mercaptopyrimidine(2-Thiobarbituri; 4,6-Dihydroxy-2-mercaptopyrimidine; 2-Thiobarbitur; 6-hydroxy-2-thioxo-2,3-dihydropyrimidin-4(1H)-one; 4(1H)-Pyrimidinone, 2,3-dihydro-6-hydroxy-2-thioxo-; 6-hydroxy-2-sulfanylidene-1,2,3,4-tetrahydropyrimidin-4-one
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| Activity |
IC50 = 279000 nM
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[2] | |||
| Compound Name |
N-(5-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide
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Investigative | Compound Info | ||
| Synonyms |
N1-(5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide; 6-Acetamido-1,2,3,4-tetrahydronaphthalen-1-one; N-(5-oxo-7,8-dihydro-6H-naphthalen-2-yl)acetamide; CHEMBL1568712; Acetamide,N-(5,6,7,8-tetrahydro-5-oxo-2-naphthalenyl)-; ACMC-20lbzu; 6-Acetamido-tetralone; CDS1_001029; PubChem17583; 6-acetamido-1-tetralone; Maybridge1_005781; 6-acetylamino-1-tetralone; Oprea1_724751; 6-(acetylamino)-1-tetralone; MLS000861004; DivK1c_002069; SCHEMBL315269; 6-(Acetylamino)tetralin-1-one; N-(5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide?; CTK5G0900; HMS557O17; KS-00000GML; DTXSID90381638; HMS2785K16; ACT03887; ZINC4271927; 4428AC; BDBM50495379; CCG-51963; MFCD00099461; SBB068653; AKOS015918160; MCULE-5002516140; PS-4443; SDCCGMLS-0066186.P001; VZ33434; AK-28125; SMR000459788; DB-078026; FT-0629685; N-(5-oxo-2-6,7,8-trihydronaphthyl)acetamide; 6-Acetamido-1,2,3,4-tetrahydronaphthalen-1-on; 611O670; J-523125; N-(5-Oxo-5,6,7,8-tetrahydro-2-naphthyl)acetamide; SR-01000641226-1; N-(5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)-acetamide; Acetamide, N-(5,6,7,8-tetrahydro-5-oxo-2-naphthalenyl)-; N-(5-oxo-5,6,7,8-tetrahydro-naphthalen-2-yl)-acetamide; N-(5-OXO-5,6,7,8-TETRAHYDRO-2-NAPHTHALENYL)ACETAMIDE
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| Activity |
IC50 = 476000 nM
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[2] | |||
| Compound Name |
2-Methyl-1H-imidazole-4-carbothioamide
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Investigative | Compound Info | ||
| Synonyms |
2-methyl-1H-imidazole-5-carbothioamide; CHEMBL3110248; 1H-Imidazole-5-carbothioamide,2-methyl-; 1H-Imidazole-5-carbothioamide, 2-methyl-; ACMC-1C27G; SCHEMBL441004; CTK4B6294; DTXSID50383850; ZINC164983; BDBM50495378; MFCD03659724; SBB086208; AKOS006230020; FT-0612902; amino(2-methylimidazol-4-yl)methane-1-thione; 2-methyl-1H-imidazole-4-carbothioamide, AldrichCPR
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| Activity |
IC50 = 495000 nM
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[2] | |||
| Compound Name |
4'-(Imidazol-1-yl)acetophenone
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Investigative | Compound Info | ||
| Synonyms |
4-(Imidazol-1-yl)acetophenone; 1-(4-(1H-Imidazol-1-yl)phenyl)ethanone; 1-(4-imidazol-1-ylphenyl)ethanone; Ro 22-3581; 4'-(1-imidazolyl)acetophenone; 1-(4-Imidazol-1-yl-phenyl)-ethanone; 1-(4-Acetylphenyl)imidazole; Ethanone, 1-[4-(1H-imidazol-1-yl)phenyl]-; TCMDC-125536; 4'-(1H-Imidazol-1-yl)acetophenone; 1-[4-(1H-Imidazol-1-yl)phenyl]ethan-1-one; MFCD00005282; 1-[4-(1H-Imidazol-1-yl)phenyl]ethanone; 1-[4-(1H-imidazol-1-yl)phenyl]-1-ethanone; 4'-(imidazol-1-yl) acetophenone; 1-acetyl-4-imidazolylbenzene; F0290-1071; 4'-(Imidazol-1-yl)methyl phenyl ketone; 4-(1-Imidazolyl)Acetophenone; MLS000780069; 1-(4-Acetylphenyl)-1H-imidazole; EINECS 233-123-5; zlchem 340; ACMC-1BPPZ; SCHEMBL611481; CHEMBL528463; CTK5J9612; DTXSID50143259; ZLC0182; BDBM181114; HMS2796H07; ZINC119721; 4`-(1H-Imidazol-1-yl)acetophenone; ANW-14276; GEO-01576; SBB042504; STK865696; AKOS000120316; AC-3232; MCULE-5402869877; SDCCGMLS-0066010.P001; VZ27913; 4'-(Imidazol-1-yl)acetophenone, 96%; NCGC00246456-01; 1-[4-(1-imidazolyl)phenyl]ethan-1-one; SC-13309; SMR000420252; SY004866; HY-109877; CS-0034130; FT-0616787; ST45012928; V0950; 1-[4-(1H-Imidazol-1-yl)phenyl]ethanone #; A-4061; US9144538, 4'-(Imidazol-1yl) acetophenome; AB00443701-03; US9138393, 4?-(Imidazol-1 yl) acetophenome; 10A-004; J-640087; J-800090; W-200067; 4 inverted exclamation mark -(1-Imidazolyl)acetophenone
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| Activity |
IC50 = 826000 nM
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[2] | |||
| Compound Name |
N-(2-Acetyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-8-yl)methanesulfonamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110259; BDBM50495366
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| Activity |
IC50 > 1000000 nM
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[2] | |||
| Compound Name |
N,1,5-Trimethyl-1H-pyrazole-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110246; N,1,5-TRIMETHYLPYRAZOLE-3-CARBOXAMIDE; 1H-Pyrazole-3-carboxamide, N,1,5-trimethyl-; SCHEMBL8568625; DTXSID70598242; BDBM50495367; MFCD09965499; ZINC13466585; AKOS006238773; ACN-051886; DS-9811; MCULE-2071786426; 1,5,N-Trimethyl-1H-pyrazole-3-carboxamide; N~3~,1,5-trimethyl-1H-pyrazole-3-carboxamide
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| Activity |
IC50 = 1094000 nM
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[2] | |||
| Compound Name |
2H-Pyrido[4,3-b]indole-2-carbothioamide, 8-chloro-1,3,4,5-tetrahydro-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3110240; BDBM50495362
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| Activity |
IC50 > 2000000 nM
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[2] | |||
| Compound Name |
1-Methyl-2-pyrrolidinone
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Investigative | Compound Info | ||
| Synonyms |
N-Methylpyrrolidone; N-Methyl-2-pyrrolidone; 1-methylpyrrolidin-2-one; Methylpyrrolidone; 1-Methyl-2-pyrrolidone; N-Methyl-2-pyrrolidinone; M-Pyrol; N-Methylpyrrolidinone; 1-Methylpyrrolidone; 2-Pyrrolidinone, 1-methyl-; 1-Methylpyrrolidinone; n-methyl-pyrrolidone; 1-Methylazacyclopentan-2-one; 1-Methyl-5-pyrrolidinone; N-methylpyrrolidin-2-one; N-Methyl-gamma-butyrolactam; N-methyl pyrrolidone; 1-methylpyrrolidine-2-one; N-methyl pyrrolidinone; Methyl-2-pyrrolidinone; 1-methyl-2-pyrrolidon; Methyl pyrrolidone; Methylpyrrolidinone; UNII-JR9CE63FPM; N-Methyl-alpha-pyrrolidone; N-Methylpyrrolidon; NSC 4594; Agsolex 1; N-Methyl-alpha-pyrrolidinone; N-methyl-pyrrolidinone; N-Methyl-2-pyrrolidon; N-Methylpyrrolid-2-one; MFCD00003193; JR9CE63FPM; N-methyl-pyrrolidin-2-one; 1-methyl-pyrrolidin-2-one; N-Methyl-.alpha.-pyrrolidone; CHEMBL12543; N-Methyl-.gamma.-butyrolactam; N-Methyl-.alpha.-pyrrolidinone; DTXSID6020856; NSC-4594; N-Methylpyrrolidinon; 1-Methyl-2-pyrrolidinone, anhydrous; 1-Methyl-2-pyrrolidinone, HPLC Grade; DSSTox_CID_856; N 0131; DSSTox_RID_75828; DSSTox_GSID_20856; pharmasolve; 2-Pyrrolidinone, methyl-; CCRIS 1633; Methylpyrrolidone, N-; HSDB 5022; Pyrrolidinone, methyl-; 1-Methyl-2-pyrrolidinone, 99.5%, for HPLC; Methylpyrrolidone [NF]; 1-Methyl-2-pyrrolidinone, 99.5+%, ACS reagent; 1-Methyl-2-pyrrolidinone, 99+%, for spectroscopy; EINECS 212-828-1; Micropure ultra; AI3-23116; N-methypyrrolidone; Pyrol M; N-methylpirrolidone; 1methylpyrrolidinone; n-methyl pyrrolidon; n-methylbutyrolactam; N-methy pyrrolidone; N-methyl-pyrolidone; N-methyl-pyrrolidon; N-methylpyrolidinone; 1-methylpyrolidinone; Microposit 2001; n-methylpyrollidinone; N-methlypyrrolidinone; N-methyl pirrolidone; N-methyl pyrollidone; N-methyl-pyrollidone; N-methylpyrrolidone-; NMP,SP Grade; 1-methyl pyrrolidone; 1-methyl-pyrrolidone; methyl-2-pyrrolidone; N-methy pyrrolidinone; N-methyl pyrolidinone; N-methyl-pyrolidinone; N-methyl- pyrrolidone; N-methylpyrro-lidinone; N-methylpyrroli-dinone; N-methylpyrrolidin-one; 1-methyl-2pyrrolidone; 1-methyl2-pyrrolidone; 1methyl-2-pyrrolidone; 1-methyl pyrrolidinone; 1-methyl-pyrrolidinone; methylpyrrolidin-2-one; N-methy-2-pyrrolidone; N-methyl 2-pyrolidone; N-methyl-2-pyrolidone; 1-methyl-2-pyrolidone; PubChem17618; N-methyl 2-pyrrolidone; N-methyl-2-pyrollidone; 1-methyl-2-pirrolidone; 1-methyl-2-pyroldinone; 1-methylpyrrolid-2-one; 1methyl-2-pyrrolidinone; ACMC-1CKWA; n-methylpyrrolidine-2one; N-methyl-2-pyrolidinone; N-methyl-2-pyrrolidinon; N-methylpyrolidin-2-one; 1-methy-2-pyrrolidinone; 1-methyl-2-pyrolidinone; N-methyl 2-pyrrolidinone; N-methyl-2-pyrollidinone; N-methyl-pyrrolid-2-one; N-methylpyrollidin-2-one; 1 -methyl-2-pyrrolidone; 1-methyl 2-pyrrolidinone; 1-methyl-2-pyrollidinone; 1-methyl-pyrrolin-2-one; N-Methylpyrrolidone-(2); NMP, N-Methylpyrrolidone; 1-Methyl-pyrrolidin-2one; N-methylpyrrolidine-2-one; WLN: T5NVTJ A; N-methyl -2-pyrrolidinone; 1 -methyl-2-pyrrolidinone; 1-methyl -2-pyrrolidinone; 1-methyl-2- pyrrolidinone; EC 212-828-1; 2-Pyrrolidone, 1-methyl-; 1-methyl-pyrrolidine-2-one; 1-N-methyl-2-pyrrolidinone; N-methyl-pyrrolidin -2-one; KSC201Q7R; 1-Methylazacyclopentane-2-one; GTPL9520; 1-Methyl-2- pyrrolidin-2-one; CTK1A1878; NSC4594; KS-000002OB; ZINC3860621; Tox21_202350; Tox21_300097; 1-Methyl-2-pyrrolidinone, 99.5%; 2447AB; ANW-38658; BDBM50353587; N-Methyl pyrrolidon (Peptide Grade); s6282; SBB060297; STL183295; N-Methyl-2-pyrrolidinone ACS reagent; AKOS000120930; 1-Methyl-2-pyrrolidinone, BioSolv(R); DB12521; MCULE-1381506705; SL 1332; 1-Methyl-2-pyrrolidone, Reagent, ACS; NCGC00247902-01; NCGC00247902-02; NCGC00253935-01; NCGC00259899-01; BR-30156; SC-18144; 1-Methyl-2-pyrrolidinone, 99%, extra pure; 1-Methyl-2-pyrrolidone (Low water content); AM20110252; CS-0017258; FT-0608052; FT-0672137; FT-0698122; FT-0700571; M0418; M3055; ST51046511; 1-Methyl-2-pyrrolidinone, analytical standard; 1-Methyl-2-pyrrolidinone, anhydrous, 99.5%; 1-Methyl-2-pyrrolidinone, for HPLC, >=99%; 1-Methyl-2-pyrrolidinone, for synthesis, 99%; C11118; M 0418; Q33103; Residual Solvent Class 2 - N-Methylpyrrolidone; 1-Methyl-2-pyrrolidinone, ReagentPlus(R), 99%; 17283-EP2272834A1; 17283-EP2272849A1; 17283-EP2275469A1; 17283-EP2287153A1; 17283-EP2287940A1; 17283-EP2289510A1; 17283-EP2289868A1; 17283-EP2289965A1; 17283-EP2295399A2; 17283-EP2298313A1; 17283-EP2298763A1; 17283-EP2298767A1; 17283-EP2298828A1; 17283-EP2301929A1; 17283-EP2301935A1; 17283-EP2301983A1; 17283-EP2305243A1; 17283-EP2305674A1; 17283-EP2308838A1; 17283-EP2308857A1; 17283-EP2308926A1; 17283-EP2309564A1; 17283-EP2309584A1; 17283-EP2311815A1; 17283-EP2311831A1; 17283-EP2314586A1; 17283-EP2314587A1; 32226-EP2301933A1; 32226-EP2311827A1; 32356-EP2298731A1; 32356-EP2301933A1; 32356-EP2311827A1; 33443-EP2287147A2; 33443-EP2292624A1; 33443-EP2295409A1; 33443-EP2301922A1; 33443-EP2308812A2; 33443-EP2311815A1; 34253-EP2269989A1; 34253-EP2270113A1; 34253-EP2272817A1; 34253-EP2272935A1; 34253-EP2277875A2; 34253-EP2292607A2; 34253-EP2298778A1; 34253-EP2305657A2; 34253-EP2308492A1; 34253-EP2311850A1; 47604-EP2269983A1; 47604-EP2269984A1; 47604-EP2269990A1; 47604-EP2277875A2; 47604-EP2292227A2; 47604-EP2298770A1; 47604-EP2298774A1; 47604-EP2301921A1; 47604-EP2301926A1; 47604-EP2305642A2; 47604-EP2305650A1; 47604-EP2305667A2; 47604-EP2308861A1; 47604-EP2308880A1; 47604-EP2311811A1; 49793-EP2272509A1; 49793-EP2272835A1; 49793-EP2272848A1; 49793-EP2274983A1; 49793-EP2277858A1; 49793-EP2283898A1; 49793-EP2292607A2; 49793-EP2295411A1; 49793-EP2298761A1; 49793-EP2305633A1; 49793-EP2305687A1; 49793-EP2308812A2; 49793-EP2308960A1; 49793-EP2311824A1; 49793-EP2311825A1; 49793-EP2380872A1; 72367-EP2279741A2; 72367-EP2287153A1; 72367-EP2287155A1; 72367-EP2292615A1; 72367-EP2295415A1; 72367-EP2298747A1; 72367-EP2308867A2; 72367-EP2308870A2; 77850-EP2272846A1; 77850-EP2277868A1; 77850-EP2277869A1; 77850-EP2277870A1; 77850-EP2284166A1; 77850-EP2292608A1; 77850-EP2292616A1; 77850-EP2298305A1; 77850-EP2298749A1; 77850-EP2305033A1; 77850-EP2308866A1; 78692-EP2277875A2; 78692-EP2292619A1; 78692-EP2305667A2; 78692-EP2305688A1; 78692-EP2375479A1; 85636-EP2292616A1; 85636-EP2298769A1; 85636-EP2305657A2; 107610-EP2272517A1; 107610-EP2298746A1; 108900-EP2281861A2; 108900-EP2298769A1; 139735-EP2269983A1; 139735-EP2269984A1; 139735-EP2292607A2; 153002-EP2280002A1; 153002-EP2287164A1; 153002-EP2289881A1; 2-PYRROLIDONE,1-METHYL MFC5 H9 N1 O1; A842053; 1-Methyl-2-pyrrolidinone, ACS reagent, >=99.0%; 2,5-Dichloro-4,6-dimethyl pyridine-3-carbonitrile; J-504921; J-803017; 1-Methyl-2-pyrrolidinone, biotech. grade, >=99.7%; 1-Methyl-2-pyrrolidinone, p.a., ACS reagent, 99%; F0001-2169
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IC50 = 34000000 nM
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| References | Top | ||||
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| REF 1 | Structure enabled design of BAZ2-ICR, a chemical probe targeting the bromodomains of BAZ2A and BAZ2B. J Med Chem. 2015 Mar 12;58(5):2553-9. | ||||
| REF 2 | Targeting low-druggability bromodomains: fragment based screening and inhibitor design against the BAZ2B bromodomain. J Med Chem. 2013 Dec 27;56(24):10183-7. | ||||
| REF 3 | [1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains. J Med Chem. 2014 Jan 23;57(2):462-76. | ||||
| REF 4 | Design and synthesis of potent and selective inhibitors of BRD7 and BRD9 bromodomains. Medchemcomm. 2015;6:1381-6. | ||||
| REF 5 | 3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands. J Med Chem. 2011 Oct 13;54(19):6761-70. | ||||
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