TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T15745	Bromodomain adjacent to zinc finger 2B	B2X8SB	3-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)propanoic acid	Investigative	76324896	C16H17ClN2O3	320.77	CC(=O)N1CCC2=C(C1)C3=C(N2CCC(=O)O)C=CC(=C3)Cl	IC50 = 66000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	B5VI9Y	2-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)-N-methylacetamide	Investigative	76314006	C16H18ClN3O2	319.78	CC(=O)N1CCC2=C(C1)C3=C(N2CC(=O)NC)C=CC(=C3)Cl	IC50 = 69000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	B5W6SY	4-[3-[2-(4-Methyltriazol-1-yl)ethyl]imidazol-4-yl]benzonitrile	Investigative	118733101	C15H14N6	278.31	CC1=CN(N=N1)CCN2C=NC=C2C3=CC=C(C=C3)C#N	IC50 ~ 50000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	B69LNE	N-Methyl-6-phenylpyridine-3-carboxamide	Investigative	24229802	C13H12N2O	212.25	CNC(=O)C1=CN=C(C=C1)C2=CC=CC=C2	IC50 = 109000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	B6P9ZN	4-[3-Methyl-5-(1-methylpyrazol-4-yl)imidazol-4-yl]benzonitrile	Investigative	118733102	C15H13N5	263.3	CN1C=C(C=N1)C2=C(N(C=N2)C)C3=CC=C(C=C3)C#N	IC50 ~ 50000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	B8GYA0	2-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)acetic acid	Investigative	76321282	C15H15ClN2O3	306.74	CC(=O)N1CCC2=C(C1)C3=C(N2CC(=O)O)C=CC(=C3)Cl	IC50 = 152000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	B8QF7H	N,2-Dimethyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide	Investigative	1511198	C18H17N5O2S	367.4	CC1=C(C=C(C=C1)C2=NN3C(=NN=C3C4=CC=CC=C42)C)S(=O)(=O)NC	IC50 ~ 100000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	B97ZUE	1-[1-(Imidazo[1,2-A]pyridin-5-Yl)-7-(Morpholin-4-Yl)indolizin-3-Yl]ethanone	Investigative	127038798	C21H20N4O2	360.4	CC(=O)C1=CC(=C2N1C=CC(=C2)N3CCOCC3)C4=CC=CC5=NC=CN54	IC50 ~ 100000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BAV60C	4-[3-[2-(4-Methyltriazol-1-yl)ethyl]-5-pyridin-3-ylimidazol-4-yl]benzonitrile	Investigative	118733098	C20H17N7	355.4	CC1=CN(N=N1)CCN2C=NC(=C2C3=CC=C(C=C3)C#N)C4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BC96XQ	N,N,2-Trimethyl-5-(3-methyl-[1,2,4]triazolo[3,4-a]phthalazin-6-yl)benzenesulfonamide	Investigative	1511199	C19H19N5O2S	381.5	CC1=C(C=C(C=C1)C2=NN3C(=NN=C3C4=CC=CC=C42)C)S(=O)(=O)N(C)C	IC50 ~ 100000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BF4XQ0	Pyrazine-2-carbothioamide	Investigative	2797467	C5H5N3S	139.18	C1=CN=C(C=N1)C(=S)N	IC50 = 190000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BG9BE4	2-Acetyl-8-fluoro-2,3,4,5-tetrahydro-1H-pyrido[4,3-B]indole	Investigative	42582730	C13H13FN2O	232.25	CC(=O)N1CCC2=C(C1)C3=C(N2)C=CC(=C3)F	IC50 = 102000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BHB3S9	N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]methanesulfonamide	Investigative	4907545	C18H17N5O2S	367.4	CC1=C(C=C(C=C1)C2=NN3C(=NN=C3C4=CC=CC=C42)C)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BI52TL	4-[5-(3-Methyl-1,2-oxazol-5-yl)-3-[2-(4-methyltriazol-1-yl)ethyl]imidazol-4-yl]benzonitrile	Investigative	118733100	C19H17N7O	359.4	CC1=NOC(=C1)C2=C(N(C=N2)CCN3C=C(N=N3)C)C4=CC=C(C=C4)C#N	IC50 ~ 50000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BIWC69	N-Ethyl-2-acetyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-sulfonamide	Investigative	76324897	C15H19N3O3S	321.4	CCNS(=O)(=O)C1=CC2=C(C=C1)NC3=C2CN(CC3)C(=O)C	IC50 = 50000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BO2UF9	N-[2-Methyl-5-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)phenyl]propanamide	Investigative	4908238	C20H19N5O	345.4	CCC(=O)NC1=C(C=CC(=C1)C2=NN3C(=NN=C3C4=CC=CC=C42)C)C	IC50 ~ 100000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BPZ92T	2-Acetyl-N-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indole-8-sulfonamide	Investigative	76317548	C14H17N3O3S	307.37	CC(=O)N1CCC2=C(C1)C3=C(N2)C=CC(=C3)S(=O)(=O)NC	IC50 = 55000 nM	Poor binder
T15745	Bromodomain adjacent to zinc finger 2B	BSTY61	3-(2-Acetyl-8-chloro-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)-N-methylpropanamide	Investigative	76310338	C17H20ClN3O2	333.8	CC(=O)N1CCC2=C(C1)C3=C(N2CCC(=O)NC)C=CC(=C3)Cl	IC50 = 143000 nM	Poor binder