TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T15745 Bromodomain adjacent to zinc finger 2B B02NOR 2H-Pyrido[4,3-b]indole-2-carbothioamide, 8-chloro-1,3,4,5-tetrahydro- Investigative 76310337 C12H12ClN3S 265.76 C1CN(CC2=C1NC3=C2C=C(C=C3)Cl)C(=S)N IC50 > 2000000 nM Non binder T15745 Bromodomain adjacent to zinc finger 2B B42QJO 4,6-Dihydroxy-2-mercaptopyrimidine Investigative 1268265 C4H4N2O2S 144.15 C1=C(NC(=S)NC1=O)O IC50 = 279000 nM Non binder T15745 Bromodomain adjacent to zinc finger 2B B5N0OS N-Methyl-2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carboxamide Investigative 24229806 C8H9NO3S 199.23 CNC(=O)C1=C2C(=CS1)OCCO2 IC50 = 241000 nM Non binder T15745 Bromodomain adjacent to zinc finger 2B B68DMW N-(2-Acetyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-8-yl)methanesulfonamide Investigative 76317549 C14H17N3O3S 307.37 CC(=O)N1CCC2=C(C1)C3=C(N2)C=CC(=C3)NS(=O)(=O)C IC50 > 1000000 nM Non binder T15745 Bromodomain adjacent to zinc finger 2B B7V3YX 2-Methyl-1H-imidazole-4-carbothioamide Investigative 2796714 C5H7N3S 141.2 CC1=NC=C(N1)C(=S)N IC50 = 495000 nM Non binder T15745 Bromodomain adjacent to zinc finger 2B B7VT1J N,1,5-Trimethyl-1H-pyrazole-3-carboxamide Investigative 19279808 C7H11N3O 153.18 CC1=CC(=NN1C)C(=O)NC IC50 = 1094000 nM Non binder T15745 Bromodomain adjacent to zinc finger 2B BB8S9I N-(5-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide Investigative 2780190 C12H13NO2 203.24 CC(=O)NC1=CC2=C(C=C1)C(=O)CCC2 IC50 = 476000 nM Non binder T15745 Bromodomain adjacent to zinc finger 2B BQ49VZ 4'-(Imidazol-1-yl)acetophenone Investigative 82316 C11H10N2O 186.21 CC(=O)C1=CC=C(C=C1)N2C=CN=C2 IC50 = 826000 nM Non binder T15745 Bromodomain adjacent to zinc finger 2B BYVF35 1-Methyl-2-pyrrolidinone Investigative 13387 C5H9NO 99.13 CN1CCCC1=O IC50 = 34000000 nM Non binder