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| Protein General Information (TTD Target) |
Top |
| Full Name |
Thioredoxin (TXN)
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Clinical trial
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Target Info
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| UniProt ID |
THIO_HUMAN
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| Gene Name |
TXN
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| Gene ID |
7295
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| Interacting TTD Target Information |
Top |
| Interacting Successful Target(s) |
Glucocorticoid receptor (NR3C1) |
Target Info
|
PPI Info
|
[1] |
| Interacting Clinical trial Target(s) |
Apoptosis signal-regulating kinase 1 (MAP3K5) |
Target Info
|
PPI Info
|
[2] |
| Interacting Literature-reported Target(s) |
JUN activation domain binding protein (COPS5) |
Target Info
|
PPI Info
|
[3] |
| Vitamin D3 up-regulated protein 1 (VDUP1) |
Target Info
|
PPI Info
|
[4] |
| References |
Top |
| REF 1 |
Interaction of mitochondrial thioredoxin with glucocorticoid receptor and NF-kappaB modulates glucocorticoid receptor and NF-kappaB signalling in HEK-293 cells. Biochem J. 2009 Aug 27;422(3):521-31.
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| REF 2 |
Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1. J Biol Chem. 2007 May 4;282(18):13680-91.
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| REF 3 |
Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. Cell. 2010 Dec 10;143(6):951-65.
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| REF 4 |
Thioredoxin regulates adipogenesis through thioredoxin-interacting protein (Txnip) protein stability. J Biol Chem. 2011 Aug 19;286(33):29139-45.
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