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| Protein General Information (TTD Target) |
Top |
| Full Name |
Suppressor of cytokine signaling 1 (SOCS1)
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Literature-reported
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Target Info
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| UniProt ID |
SOCS1_HUMAN
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| Gene Name |
SOCS1
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| Gene ID |
8651
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| References |
Top |
| REF 1 |
Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1. Mol Cell Biol. 2002 May;22(10):3316-26.
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| REF 2 |
SOCS1 links cytokine signaling to p53 and senescence. Mol Cell. 2009 Dec 11;36(5):754-67.
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| REF 3 |
SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation. J Biol Chem. 2006 Mar 3;281(9):5559-66.
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| REF 4 |
Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation. EMBO J. 1999 Feb 15;18(4):904-15.
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