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Protein General Information (TTD Target) |
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Full Name |
Tyrosine-protein kinase 6 (PTK6)
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Clinical trial
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Target Info
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UniProt ID |
PTK6_HUMAN
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Gene Name |
PTK6
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Gene ID |
5753
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Interacting TTD Target Information |
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Interacting Successful Target(s) |
Epidermal growth factor receptor (EGFR) |
Target Info
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PPI Info
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[1] |
Interacting Clinical trial Target(s) |
Erbb3 tyrosine kinase receptor (Erbb-3) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor. J Biol Chem. 1996 Nov 29;271(48):30956-63.
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REF 2 |
Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation. Oncogene. 2000 Nov 16;19(48):5471-6.
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