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| Protein General Information (TTD Target) |
Top |
| Full Name |
Presenilin 1 (PSEN1)
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Clinical trial
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Target Info
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| UniProt ID |
PSN1_HUMAN
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| Gene Name |
PSEN1
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| Gene ID |
5663
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| References |
Top |
| REF 1 |
Direct association of presenilin-1 with beta-catenin. FEBS Lett. 1998 Aug 14;433(1-2):73-7.
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| REF 2 |
Coordinated and widespread expression of gamma-secretase in vivo: evidence for size and molecular heterogeneity. Neurobiol Dis. 2004 Nov;17(2):260-72.
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| REF 3 |
APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes. J Biol Chem. 2003 Feb 28;278(9):7374-80.
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| REF 4 |
Association between Presenilin-1 and TRAF6 modulates regulated intramembrane proteolysis of the p75NTR neurotrophin receptor. J Neurochem. 2009 Jan;108(1):216-30.
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