Protein-Protein Interaction Details
Protein General Information | Top | ||||
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Full Name | Proteasome subunit alpha type-3 (PSMA3) | ||||
UniProt ID | PSA3_HUMAN | ||||
Gene Name | PSMA3 | ||||
Gene ID | 5684 |
Interacting TTD Target Information | Top | ||||
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Interacting Clinical trial Target(s) | Aurora kinase B (AURKB) | Target Info | PPI Info | [1] | |
Interacting Patented-recorded Target(s) | Proteasome beta-2 (PS beta-2) | Target Info | PPI Info | [2] | |
Proteasome beta-5 (PS beta-5) | Target Info | PPI Info | [3] | ||
Ubiquitin C-terminal hydrolase UCH37 (UCHL5) | Target Info | PPI Info | [4] | ||
Interacting Literature-reported Target(s) | Renal carcinoma antigen NY-REN-54 (UBE3A) | Target Info | PPI Info | [5] |
References | Top | ||||
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REF 1 | Human aurora-B binds to a proteasome alpha-subunit HC8 and undergoes degradation in a proteasome-dependent manner. Mol Cell Biochem. 2003 Dec;254(1-2):157-62. | ||||
REF 2 | Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509. | ||||
REF 3 | Protein-protein interactions among human 20S proteasome subunits and proteassemblin. Biochem Biophys Res Commun. 2004 Feb 6;314(2):523-8. | ||||
REF 4 | Distinct modes of regulation of the Uch37 deubiquitinating enzyme in the proteasome and in the Ino80 chromatin-remodeling complex. Mol Cell. 2008 Sep 26;31(6):909-17. | ||||
REF 5 | Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes. Mol Cell Biol. 2012 Aug;32(15):3095-106. |
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