Protein-Protein Interaction Details
| Protein General Information (TTD Target) | Top | ||||
|---|---|---|---|---|---|
| Full Name | Junction plakoglobin (JUP) | Literature-reported | Target Info | ||
| UniProt ID | PLAK_HUMAN | ||||
| Gene Name | JUP | ||||
| Gene ID | 3728 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Successful Target(s) | Epidermal growth factor receptor (EGFR) | Target Info | PPI Info | [1] | |
| Erbb2 tyrosine kinase receptor (HER2) | Target Info | PPI Info | [2] | ||
| Beta-catenin (CTNNB1) | Target Info | PPI Info | [3] | ||
| Interacting Clinical trial Target(s) | Neural cadherin (CDH2) | Target Info | PPI Info | [4] | |
| Interacting Literature-reported Target(s) | Epithelial cadherin (CDH1) | Target Info | PPI Info | [5] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92. | ||||
| REF 2 | c-erbB-2 gene product directly associates with beta-catenin and plakoglobin. Biochem Biophys Res Commun. 1995 Mar 28;208(3):1067-72. | ||||
| REF 3 | Expression and interaction of different catenins in colorectal carcinoma cells. Int J Mol Med. 2001 Dec;8(6):695-8. | ||||
| REF 4 | A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells. J Cell Sci. 2003 Dec 15;116(Pt 24):4985-95. | ||||
| REF 5 | Dynamics of cadherin/catenin complex formation: novel protein interactions and pathways of complex assembly. J Cell Biol. 1994 Jun;125(6):1327-40. | ||||
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