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| Protein General Information |
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| Full Name |
E3 SUMO-protein ligase PIAS2 (PIAS2)
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| UniProt ID |
PIAS2_HUMAN
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| Gene Name |
PIAS2
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| Gene ID |
9063
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| Interacting TTD Target Information |
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| Interacting Successful Target(s) |
RAC-alpha serine/threonine-protein kinase (AKT1) |
Target Info
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PPI Info
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[1] |
| Interacting Clinical trial Target(s) |
Cellular tumor antigen p53 (TP53) |
Target Info
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PPI Info
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[2] |
| References |
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| REF 1 |
A crosstalk between hSiah2 and Pias E3-ligases modulates Pias-dependent activation. Oncogene. 2007 Oct 11;26(46):6665-76.
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| REF 2 |
Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2872-7.
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