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| Protein General Information |
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| Full Name |
E3 ubiquitin-protein ligase pellino homolog 2 (PELI2)
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| UniProt ID |
PELI2_HUMAN
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| Gene Name |
PELI2
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| Gene ID |
57161
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Renal carcinoma antigen NY-REN-64 (IRAK-4) |
Target Info
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PPI Info
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[1] |
| Interacting Patented-recorded Target(s) |
IL-1 receptor-associated kinase 1 (IRAK1) |
Target Info
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PPI Info
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[2] |
| References |
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| REF 1 |
Kinase-active interleukin-1 receptor-associated kinases promote polyubiquitination and degradation of the Pellino family: direct evidence for PELLINO proteins being ubiquitin-protein isopeptide ligases. J Biol Chem. 2007 Oct 12;282(41):29729-37.
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| REF 2 |
Pellino proteins are more than scaffold proteins in TLR/IL-1R signalling: a role as novel RING E3-ubiquitin-ligases. FEBS Lett. 2006 Aug 21;580(19):4697-702.
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